Click here to switch to the map view.

The map label for this gene is msrB

Identifier: 16126422

GI number: 16126422

Start: 2392677

End: 2393156

Strand: Direct

Name: msrB

Synonym: CC_2183

Alternate gene names: 16126422

Gene position: 2392677-2393156 (Clockwise)

Preceding gene: 16126420

Following gene: 16126423

Centisome position: 59.56

GC content: 69.58

Gene sequence:

>480_bases
ATGACAGACGCAGCCACCCTTTCAACCGCCGGCTTTGACCTGACCCCGCCGACCGAGGCCGAACGCGAACGCCTGGAGGC
CAATCTGACGGCCGAGGAGGCTCGCGTCCTGCTGCACCACGGCACCGAGGCGCCGTTCTGCGGCGGCCTGCTGGGCGAAA
AGAGCCCCGGCGTCTATGGCTGCCGCCTCTGCGGCCTGCCGCTGTTCAAGCACGAGACCAAGTTCGAGAGCGGCACAGGC
TGGCCCAGCTTCTACGCGCCGTTCGCCGAGGACCACGTGGTCGGCGTGCGCGACACCTCCTACGGCATGGTCCGCATCGA
GACCCGCTGCGCCCGCTGCGACAGCCACCAGGGCCATGTCTTCCCCGACGGCCCGGCGCCGACGCGGCTGCGCTACTGCA
TCAACTCGGTGTCGCTGCAGTTCGTGAAGGCGGGCGCTCCCCTGCCCGATCCGCTGCACCGGGGCGACAAGATCACCTGA

Upstream 100 bases:

>100_bases
TTCCCAATCGGCCCAGCCCGGCTGCAGAAAGGCGACGGCGACGGTCATGTGGGGCTCCTGGTGCTACCGAAAAGACGCTC
AAGCGCTTACACTGGCGTTC

Downstream 100 bases:

>100_bases
CCCAAAGGGAAATTTGACGGCGAGCCTCTTTCGACATCCCCTCTGCCAAAAGCTCGATGATGAGCGACGGCGGAGGGAAC
ATGTCCAAAGCGGCTTCAGC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYGCRLCGLPLFKHETKFESGTG
WPSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHVFPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT

Sequences:

>Translated_159_residues
MTDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYGCRLCGLPLFKHETKFESGTG
WPSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHVFPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT
>Mature_158_residues
TDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYGCRLCGLPLFKHETKFESGTGW
PSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHVFPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI37620216, Length=123, Percent_Identity=47.9674796747967, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI301336164, Length=123, Percent_Identity=47.9674796747967, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI301336162, Length=123, Percent_Identity=47.9674796747967, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI73089054, Length=123, Percent_Identity=47.9674796747967, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI117606353, Length=146, Percent_Identity=42.4657534246575, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788077, Length=120, Percent_Identity=54.1666666666667, Blast_Score=143, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=129, Percent_Identity=42.6356589147287, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI115532676, Length=129, Percent_Identity=42.6356589147287, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319816, Length=131, Percent_Identity=35.1145038167939, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24645799, Length=149, Percent_Identity=42.9530201342282, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221378664, Length=129, Percent_Identity=45.7364341085271, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45553335, Length=133, Percent_Identity=45.1127819548872, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21356369, Length=133, Percent_Identity=45.1127819548872, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI221378662, Length=136, Percent_Identity=43.3823529411765, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24645801, Length=160, Percent_Identity=40, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645804, Length=144, Percent_Identity=41.6666666666667, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_CAUCN (B8GY23)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002517638.1
- ProteinModelPortal:   B8GY23
- SMR:   B8GY23
- GeneID:   7332630
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_02265
- OMA:   RPWTGEL
- ProtClustDB:   PRK00222
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 17300; Mature: 17168

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: ACT_SITE 133-133

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYG
CCCCCCEECCCCCCCCCCHHHHHHHHCCCCHHHHEEEEECCCCCCCCCCCCCCCCCCEEE
CRLCGLPLFKHETKFESGTGWPSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHV
EHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCCCCCC
FPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT
CCCCCCCHHHHHHHHHHHEEEEECCCCCCCHHCCCCCCC
>Mature Secondary Structure 
TDAATLSTAGFDLTPPTEAERERLEANLTAEEARVLLHHGTEAPFCGGLLGEKSPGVYG
CCCCCEECCCCCCCCCCHHHHHHHHCCCCHHHHEEEEECCCCCCCCCCCCCCCCCCEEE
CRLCGLPLFKHETKFESGTGWPSFYAPFAEDHVVGVRDTSYGMVRIETRCARCDSHQGHV
EHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEHHCCCCCCCCC
FPDGPAPTRLRYCINSVSLQFVKAGAPLPDPLHRGDKIT
CCCCCCCHHHHHHHHHHHEEEEECCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA