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The map label for this gene is tesA [H]

Identifier: 16126004

GI number: 16126004

Start: 1942296

End: 1942928

Strand: Direct

Name: tesA [H]

Synonym: CC_1760

Alternate gene names: 16126004

Gene position: 1942296-1942928 (Clockwise)

Preceding gene: 16126001

Following gene: 16126006

Centisome position: 48.35

GC content: 67.61

Gene sequence:

>633_bases
ATGAGCCAGACCGCACACCGTTTTCCCAACCGCCGACGTTTTTTGCTGGGGATCGGCCTGCTGAGCCAGATCGCCGCCGC
GCCGAAGCCGGTGGTGATCACCGTGCTCGGCGACTCCATCACCGCCGGGCTCGGCTTGCCCGCGCGCGAGGCCATGCCCG
CGCAGTTACAGTCAGCGCTGGGGCGACGTGGGATCTCAGCGGTCGTAAGACCCGCCGGCGTCTCGGGCGACACAAGCGGC
GGCGGCTTGGCCCGGCTTGGCTTCAGCGTCTCGAAGGACACACAACTCTGCGTGGTGGCGCTCGGCGGCAACGATCTGCT
GCAGGGCGTCGATCCGGCTCAGACCAAGGCGAACCTTCGCGGCGTGCTGCAGAAGCTCAAGGCCCGGAACGTCCGTGCGG
TGCTGGTCGGCGTGGCCGCGCCAGCCAGGATCGGCGCCAGCTACGCGCGCGACTTCAACGCCATTTATCCGAGCCTGGCC
AAGGAGTTCGGCGTGCCGCTTTACGCGAATATCCTCGCGGGGGTCGTCGGCAATCCGGCGTTGATGCAGCGCGACGGAAT
TCATCCGAACGCTCAGGGCGCCAAGAAGATCGGCGAGGCGCTGGCCGCTGTCGTCGCCAAGGCGGTGAGTTAG

Upstream 100 bases:

>100_bases
CGTCGAGGACCAGAGGCGCGGCGGGCGTAACGTCGTCGGACATGGGTTTTCCTGCGAGGCCGGTCCTTGTTTGGCCGGCA
GCTAGACTACATAGGAAAGC

Downstream 100 bases:

>100_bases
GGGCGCGGCCACTCGACGCATCTGCGCCGTTTGCGGGTTCTAGCTGAAGTGCGACGGAGAGCCTGGGCAGGATGACGGGG
AGGGGGCCTCCTGTCACGTC

Product: acyl-CoA thioesterase I

Products: NA

Alternate protein names: Lecithinase B; Lysophospholipase L1; Protease I [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSQTAHRFPNRRRFLLGIGLLSQIAAAPKPVVITVLGDSITAGLGLPAREAMPAQLQSALGRRGISAVVRPAGVSGDTSG
GGLARLGFSVSKDTQLCVVALGGNDLLQGVDPAQTKANLRGVLQKLKARNVRAVLVGVAAPARIGASYARDFNAIYPSLA
KEFGVPLYANILAGVVGNPALMQRDGIHPNAQGAKKIGEALAAVVAKAVS

Sequences:

>Translated_210_residues
MSQTAHRFPNRRRFLLGIGLLSQIAAAPKPVVITVLGDSITAGLGLPAREAMPAQLQSALGRRGISAVVRPAGVSGDTSG
GGLARLGFSVSKDTQLCVVALGGNDLLQGVDPAQTKANLRGVLQKLKARNVRAVLVGVAAPARIGASYARDFNAIYPSLA
KEFGVPLYANILAGVVGNPALMQRDGIHPNAQGAKKIGEALAAVVAKAVS
>Mature_209_residues
SQTAHRFPNRRRFLLGIGLLSQIAAAPKPVVITVLGDSITAGLGLPAREAMPAQLQSALGRRGISAVVRPAGVSGDTSGG
GLARLGFSVSKDTQLCVVALGGNDLLQGVDPAQTKANLRGVLQKLKARNVRAVLVGVAAPARIGASYARDFNAIYPSLAK
EFGVPLYANILAGVVGNPALMQRDGIHPNAQGAKKIGEALAAVVAKAVS

Specific function: Hydrolyzes only long chain acyl thioesters (C12-C18). Specificity similar to chymotrypsin [H]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDSL' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786702, Length=198, Percent_Identity=39.8989898989899, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013830
- InterPro:   IPR013831
- InterPro:   IPR001087
- InterPro:   IPR008265 [H]

Pfam domain/function: PF00657 Lipase_GDSL [H]

EC number: =3.1.1.5 [H]

Molecular weight: Translated: 21487; Mature: 21356

Theoretical pI: Translated: 11.54; Mature: 11.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTAHRFPNRRRFLLGIGLLSQIAAAPKPVVITVLGDSITAGLGLPAREAMPAQLQSAL
CCCCCHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHCCCCCHHHCCHHHHHHHH
GRRGISAVVRPAGVSGDTSGGGLARLGFSVSKDTQLCVVALGGNDLLQGVDPAQTKANLR
HHCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCHHHCCCCHHHHHHHHH
GVLQKLKARNVRAVLVGVAAPARIGASYARDFNAIYPSLAKEFGVPLYANILAGVVGNPA
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
LMQRDGIHPNAQGAKKIGEALAAVVAKAVS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQTAHRFPNRRRFLLGIGLLSQIAAAPKPVVITVLGDSITAGLGLPAREAMPAQLQSAL
CCCCHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHCCCCCHHHCCHHHHHHHH
GRRGISAVVRPAGVSGDTSGGGLARLGFSVSKDTQLCVVALGGNDLLQGVDPAQTKANLR
HHCCHHHHHCCCCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCHHHCCCCHHHHHHHHH
GVLQKLKARNVRAVLVGVAAPARIGASYARDFNAIYPSLAKEFGVPLYANILAGVVGNPA
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
LMQRDGIHPNAQGAKKIGEALAAVVAKAVS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]