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The map label for this gene is ndk

Identifier: 16125944

GI number: 16125944

Start: 1872296

End: 1872715

Strand: Direct

Name: ndk

Synonym: CC_1699

Alternate gene names: 16125944

Gene position: 1872296-1872715 (Clockwise)

Preceding gene: 16125941

Following gene: 16125948

Centisome position: 46.61

GC content: 62.86

Gene sequence:

>420_bases
GTGACCGAACGCACCTTCTCGATCATCAAGCCGGACGCCACGCGTCGTAACCTGACCGGCGCCATCAACGCTGTGATCGA
GGCCGCCGGCCTGCGCATCGTCGCTCAGCGCCGCGTGAAGCTGACCGAAGCCCAAGCCAAGAAGTTCTACGAAGTCCACG
CCGAGCGTCCGTTCTACGGCGAACTCGTGGGCCAGATGACCGCCGAGCCGGTCGTCGTTCAGGTGCTGCAGGGCGACAAC
GCCGTCCTGAAGTACCGCGAAGTCATGGGCGCCACGAACCCGGAAAACGCTGACGAAGGCACCATCCGCAAGCTGTTCGC
CCTGTCGATCGGTGAAAACTCGGTCCACGGCTCGGACAGCCTGGAGAACGCCGGCATCGAAATCGCCCAGTTCTTCACGG
AAGACGAAATCGTCGGCTAA

Upstream 100 bases:

>100_bases
GCATTTTTGTGAAGCTTACGCGGTGGGGTTGGCGAGGGCGGGGCGCACGGCTATAAGCCCGCAACCTCCCAATTCACAAC
TTTTCTGTGAGATCACTGTC

Downstream 100 bases:

>100_bases
TCGCCGTCGACATTTCTGATGACGCAGAGCGGCCGGATCGGTGACGATCCGGCCGTTTTCTTTTGCGCGGGAGTCTGGGC
GTGCAGCACTACGGACGCGG

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MTERTFSIIKPDATRRNLTGAINAVIEAAGLRIVAQRRVKLTEAQAKKFYEVHAERPFYGELVGQMTAEPVVVQVLQGDN
AVLKYREVMGATNPENADEGTIRKLFALSIGENSVHGSDSLENAGIEIAQFFTEDEIVG

Sequences:

>Translated_139_residues
MTERTFSIIKPDATRRNLTGAINAVIEAAGLRIVAQRRVKLTEAQAKKFYEVHAERPFYGELVGQMTAEPVVVQVLQGDN
AVLKYREVMGATNPENADEGTIRKLFALSIGENSVHGSDSLENAGIEIAQFFTEDEIVG
>Mature_138_residues
TERTFSIIKPDATRRNLTGAINAVIEAAGLRIVAQRRVKLTEAQAKKFYEVHAERPFYGELVGQMTAEPVVVQVLQGDNA
VLKYREVMGATNPENADEGTIRKLFALSIGENSVHGSDSLENAGIEIAQFFTEDEIVG

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family

Homologues:

Organism=Homo sapiens, GI37693993, Length=136, Percent_Identity=44.8529411764706, Blast_Score=118, Evalue=1e-27,
Organism=Homo sapiens, GI66392227, Length=136, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI66392205, Length=136, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI4505409, Length=136, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI66392192, Length=136, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI66392203, Length=136, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI38045913, Length=137, Percent_Identity=40.8759124087591, Blast_Score=106, Evalue=6e-24,
Organism=Homo sapiens, GI4557797, Length=137, Percent_Identity=40.8759124087591, Blast_Score=106, Evalue=7e-24,
Organism=Homo sapiens, GI4826862, Length=136, Percent_Identity=35.2941176470588, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI37574614, Length=134, Percent_Identity=32.089552238806, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI7019465, Length=134, Percent_Identity=32.089552238806, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI5031951, Length=134, Percent_Identity=32.8358208955224, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788866, Length=136, Percent_Identity=52.2058823529412, Blast_Score=140, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17506807, Length=136, Percent_Identity=40.4411764705882, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322783, Length=137, Percent_Identity=37.2262773722628, Blast_Score=104, Evalue=6e-24,
Organism=Drosophila melanogaster, GI45549037, Length=136, Percent_Identity=41.1764705882353, Blast_Score=108, Evalue=9e-25,
Organism=Drosophila melanogaster, GI18860097, Length=142, Percent_Identity=33.0985915492958, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NDK_CAUCN (B8GW43)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002517143.1
- ProteinModelPortal:   B8GW43
- SMR:   B8GW43
- GeneID:   7331235
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01770
- OMA:   ERPFFGA
- ProtClustDB:   PRK00668
- GO:   GO:0005737
- HAMAP:   MF_00451
- InterPro:   IPR001564
- InterPro:   IPR023005
- Gene3D:   G3DSA:3.30.70.141
- PANTHER:   PTHR11349
- PRINTS:   PR01243
- SMART:   SM00562

Pfam domain/function: PF00334 NDK; SSF54919 NDK

EC number: =2.7.4.6

Molecular weight: Translated: 15250; Mature: 15119

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00469 NDP_KINASES

Important sites: ACT_SITE 116-116 BINDING 10-10 BINDING 58-58 BINDING 86-86 BINDING 92-92 BINDING 103-103 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERTFSIIKPDATRRNLTGAINAVIEAAGLRIVAQRRVKLTEAQAKKFYEVHAERPFYG
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ELVGQMTAEPVVVQVLQGDNAVLKYREVMGATNPENADEGTIRKLFALSIGENSVHGSDS
HHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
LENAGIEIAQFFTEDEIVG
CCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TERTFSIIKPDATRRNLTGAINAVIEAAGLRIVAQRRVKLTEAQAKKFYEVHAERPFYG
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ELVGQMTAEPVVVQVLQGDNAVLKYREVMGATNPENADEGTIRKLFALSIGENSVHGSDS
HHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
LENAGIEIAQFFTEDEIVG
CCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA