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The map label for this gene is der [H]

Identifier: 16125900

GI number: 16125900

Start: 1826908

End: 1828674

Strand: Direct

Name: der [H]

Synonym: CC_1654

Alternate gene names: 16125900

Gene position: 1826908-1828674 (Clockwise)

Preceding gene: 16125899

Following gene: 16125910

Centisome position: 45.48

GC content: 68.53

Gene sequence:

>1767_bases
ATGCCTTTGAAACTCGCCATCGTCGGCCGGCCCAATGTGGGCAAGTCCACGCTGTTCAACCGCCTCGCCGGCAAGAAGCT
GGCGATCGTCGACGACCAGCCGGGCGTCACGCGCGACCGCCGTTACGCCTCCGGCAGCCTGGGGGATCTTGAGCTCGAGC
TCATCGATACCGCCGGCTTCGAGGATGTCGACGACTCCAGCCTTGAGGCGCGGATGCGCGCCCAGACCGAGGCCGCGATC
GAAGAGGCGGACGTCTCGCTGTTCGTGTTCGACAGCCGCGAGGGCGTCACCGCGCTCGACGAGGTGTTCGCCGCCATCCT
GCGCAAGCGCGACAAGCCCGTCATCGTCGCGGCCAACAAGGCCGAGGGCAAGGCGGGCGAGGCCGGCGCCGGCGAAGCCT
TCCGTCTAGGCCTGGGCGAGCCGATCCCGATCTCGGGTGAGCACGGCGAGGGCATGGCTGAGCTCTATGCCGCTCTGCTG
GCCTTCGAGCCTCAAGTCGAGGCCGGCGACGACGAGGACGACGACAGCAAGCCGATCCGCATCGCCATCATCGGCCGTCC
GAACGCGGGCAAGTCGACGCTGGTGAACCGCCTCTTGGGCGAAGATCGCCTGCTGACCGGTCCCGAAGCGGGCATCACCC
GCGATTCCATCTCGGTCGACTGGGAATGGGACGGCCGCAAGATCCGCCTGGTCGACACGGCCGGCCTGCGCCGCAAGGCC
AAGGTCCAGGACAAGCTGGAGAAGCTGTCGACCGCCGACACCATCCGCGCCATCACCTTCGCCGAGGTGGTGCTGTTGGT
CATGGACGCCACCCATCCGTTCGAGATCCAGGACCTGCAGATCGCCGACCTGGCGGAGCGGGAAGGGCGGGCCGTGGTGT
TCGTGCTGGCCAAGTGGGACCTGATCGAGGACCAGGCCGCGCACCTTACCGCCTTCCGCGAGCACGCCGAGCGCATGTTG
CCCCAGCTGCGCGGCGCGCCGGTCGTGGCGCTCTCGGGCGAGACCGGCAAGGGCATCGGCCACCTGATGCCGGCGGTGAT
CAAGACGCACCGCGACTGGTCGACCAAGGTCAAGACCCGCGACCTGAACGATTGGCTGCAGATGGCCATGCAGCGTCACC
CGCCGCCTGCGGTCAGTGGTCGTCGCGTGAAGCCCAAGTACATGGCCCAGACCAAGGCTCGTCCGCCGACGTTCGTGCTG
TTTTCCAGCCGCGCCGACCAGATGCCCGATCACTATCGGCGCTACCTGATCAACAGCCTGCGCGAGAGTTTCGATCTGCC
AGGCGTGCCGCTGCGGATCACGATCAAGTCGGGCGCGAACCCCTACGCCGATGGCGAGGCCAAGGGGCACAGCGGCCGTG
GCAAGCGCGAGTTCGAGCGCCGGGAGCGGGAAGAAGAGCGCATCCGCGCCTCGCGCAACACGGTCAAGAAGTCCAAGCGT
CTGGCCGCTGAAGCCGCCGCCAAGGCGGCGGAGGCTGCTGGCTTGCCGGATCCGGGTAAGGTGGCGGTGAAGCCCGTGAA
GAAAAAGGGCCCCGCCGTCGCAAAGGCGGCTCCGAGCGAGGCCGCCGGTGTGTCGGAACCCGGCAAGGCGGCGGTCAAGT
CCGTGAAGGCCAAGGGACCGCGCGCCCAGAAGAAGGTCGCCACGACGCCCAGCTACAAGGTCGGGACCAAGACGGCCGGC
GGCAAGGCCGCCGCGCCGCGCCGTCCGGCTGCGGGTTCGCGCACAGTGCGTGGGAACACCGGGCCCGGTCGCCCTAAAGG
GCGCTAA

Upstream 100 bases:

>100_bases
GGCCCAAACCCTTGAAGCCCGGGTCGGCGCAAGCCGGCCCGGGCCTTCGCTTTTTCGGCTCCCTTTTGCGATAGGGGCGA
AAATCGACTACTGGACGCCT

Downstream 100 bases:

>100_bases
GCAGAGCCGAAAATGGCCGCCGCTTTGTCAGCGGCGGCCATCTGGAACCCGTTACTGCGGGTTCGTCCCCCCACGGGATC
AGAATTCTTCCCAATCGCTG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MPLKLAIVGRPNVGKSTLFNRLAGKKLAIVDDQPGVTRDRRYASGSLGDLELELIDTAGFEDVDDSSLEARMRAQTEAAI
EEADVSLFVFDSREGVTALDEVFAAILRKRDKPVIVAANKAEGKAGEAGAGEAFRLGLGEPIPISGEHGEGMAELYAALL
AFEPQVEAGDDEDDDSKPIRIAIIGRPNAGKSTLVNRLLGEDRLLTGPEAGITRDSISVDWEWDGRKIRLVDTAGLRRKA
KVQDKLEKLSTADTIRAITFAEVVLLVMDATHPFEIQDLQIADLAEREGRAVVFVLAKWDLIEDQAAHLTAFREHAERML
PQLRGAPVVALSGETGKGIGHLMPAVIKTHRDWSTKVKTRDLNDWLQMAMQRHPPPAVSGRRVKPKYMAQTKARPPTFVL
FSSRADQMPDHYRRYLINSLRESFDLPGVPLRITIKSGANPYADGEAKGHSGRGKREFERREREEERIRASRNTVKKSKR
LAAEAAAKAAEAAGLPDPGKVAVKPVKKKGPAVAKAAPSEAAGVSEPGKAAVKSVKAKGPRAQKKVATTPSYKVGTKTAG
GKAAAPRRPAAGSRTVRGNTGPGRPKGR

Sequences:

>Translated_588_residues
MPLKLAIVGRPNVGKSTLFNRLAGKKLAIVDDQPGVTRDRRYASGSLGDLELELIDTAGFEDVDDSSLEARMRAQTEAAI
EEADVSLFVFDSREGVTALDEVFAAILRKRDKPVIVAANKAEGKAGEAGAGEAFRLGLGEPIPISGEHGEGMAELYAALL
AFEPQVEAGDDEDDDSKPIRIAIIGRPNAGKSTLVNRLLGEDRLLTGPEAGITRDSISVDWEWDGRKIRLVDTAGLRRKA
KVQDKLEKLSTADTIRAITFAEVVLLVMDATHPFEIQDLQIADLAEREGRAVVFVLAKWDLIEDQAAHLTAFREHAERML
PQLRGAPVVALSGETGKGIGHLMPAVIKTHRDWSTKVKTRDLNDWLQMAMQRHPPPAVSGRRVKPKYMAQTKARPPTFVL
FSSRADQMPDHYRRYLINSLRESFDLPGVPLRITIKSGANPYADGEAKGHSGRGKREFERREREEERIRASRNTVKKSKR
LAAEAAAKAAEAAGLPDPGKVAVKPVKKKGPAVAKAAPSEAAGVSEPGKAAVKSVKAKGPRAQKKVATTPSYKVGTKTAG
GKAAAPRRPAAGSRTVRGNTGPGRPKGR
>Mature_587_residues
PLKLAIVGRPNVGKSTLFNRLAGKKLAIVDDQPGVTRDRRYASGSLGDLELELIDTAGFEDVDDSSLEARMRAQTEAAIE
EADVSLFVFDSREGVTALDEVFAAILRKRDKPVIVAANKAEGKAGEAGAGEAFRLGLGEPIPISGEHGEGMAELYAALLA
FEPQVEAGDDEDDDSKPIRIAIIGRPNAGKSTLVNRLLGEDRLLTGPEAGITRDSISVDWEWDGRKIRLVDTAGLRRKAK
VQDKLEKLSTADTIRAITFAEVVLLVMDATHPFEIQDLQIADLAEREGRAVVFVLAKWDLIEDQAAHLTAFREHAERMLP
QLRGAPVVALSGETGKGIGHLMPAVIKTHRDWSTKVKTRDLNDWLQMAMQRHPPPAVSGRRVKPKYMAQTKARPPTFVLF
SSRADQMPDHYRRYLINSLRESFDLPGVPLRITIKSGANPYADGEAKGHSGRGKREFERREREEERIRASRNTVKKSKRL
AAEAAAKAAEAAGLPDPGKVAVKPVKKKGPAVAKAAPSEAAGVSEPGKAAVKSVKAKGPRAQKKVATTPSYKVGTKTAGG
KAAAPRRPAAGSRTVRGNTGPGRPKGR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=465, Percent_Identity=40.4301075268817, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=31.3333333333333, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI2367268, Length=175, Percent_Identity=34.2857142857143, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=185, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 63538; Mature: 63407

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKLAIVGRPNVGKSTLFNRLAGKKLAIVDDQPGVTRDRRYASGSLGDLELELIDTAGF
CCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCC
EDVDDSSLEARMRAQTEAAIEEADVSLFVFDSREGVTALDEVFAAILRKRDKPVIVAANK
CCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECC
AEGKAGEAGAGEAFRLGLGEPIPISGEHGEGMAELYAALLAFEPQVEAGDDEDDDSKPIR
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
IAIIGRPNAGKSTLVNRLLGEDRLLTGPEAGITRDSISVDWEWDGRKIRLVDTAGLRRKA
EEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHH
KVQDKLEKLSTADTIRAITFAEVVLLVMDATHPFEIQDLQIADLAEREGRAVVFVLAKWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCCEEEEEEEECC
LIEDQAAHLTAFREHAERMLPQLRGAPVVALSGETGKGIGHLMPAVIKTHRDWSTKVKTR
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECC
DLNDWLQMAMQRHPPPAVSGRRVKPKYMAQTKARPPTFVLFSSRADQMPDHYRRYLINSL
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
RESFDLPGVPLRITIKSGANPYADGEAKGHSGRGKREFERREREEERIRASRNTVKKSKR
HHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAEAAAKAAEAAGLPDPGKVAVKPVKKKGPAVAKAAPSEAAGVSEPGKAAVKSVKAKGP
HHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCC
RAQKKVATTPSYKVGTKTAGGKAAAPRRPAAGSRTVRGNTGPGRPKGR
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
PLKLAIVGRPNVGKSTLFNRLAGKKLAIVDDQPGVTRDRRYASGSLGDLELELIDTAGF
CEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCC
EDVDDSSLEARMRAQTEAAIEEADVSLFVFDSREGVTALDEVFAAILRKRDKPVIVAANK
CCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECC
AEGKAGEAGAGEAFRLGLGEPIPISGEHGEGMAELYAALLAFEPQVEAGDDEDDDSKPIR
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEE
IAIIGRPNAGKSTLVNRLLGEDRLLTGPEAGITRDSISVDWEWDGRKIRLVDTAGLRRKA
EEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHH
KVQDKLEKLSTADTIRAITFAEVVLLVMDATHPFEIQDLQIADLAEREGRAVVFVLAKWD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCCEEEEEEEECC
LIEDQAAHLTAFREHAERMLPQLRGAPVVALSGETGKGIGHLMPAVIKTHRDWSTKVKTR
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECC
DLNDWLQMAMQRHPPPAVSGRRVKPKYMAQTKARPPTFVLFSSRADQMPDHYRRYLINSL
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
RESFDLPGVPLRITIKSGANPYADGEAKGHSGRGKREFERREREEERIRASRNTVKKSKR
HHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAEAAAKAAEAAGLPDPGKVAVKPVKKKGPAVAKAAPSEAAGVSEPGKAAVKSVKAKGP
HHHHHHHHHHHHCCCCCCCCEEEEEHHCCCCCCCCCCCCHHCCCCCCHHHHHHHHHCCCC
RAQKKVATTPSYKVGTKTAGGKAAAPRRPAAGSRTVRGNTGPGRPKGR
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA