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The map label for this gene is cpg2 [H]

Identifier: 16125852

GI number: 16125852

Start: 1777838

End: 1779082

Strand: Direct

Name: cpg2 [H]

Synonym: CC_1605

Alternate gene names: 16125852

Gene position: 1777838-1779082 (Clockwise)

Preceding gene: 16125851

Following gene: 16125853

Centisome position: 44.26

GC content: 67.07

Gene sequence:

>1245_bases
ATGCATCTCACGTCAGAAGATCGCAGCGTTCTAGATCGGATCGCGCAGGATGGTGGCCGGATCGTCGACCGGGCGGTCGA
TTGGTGCGCCATAAACTCGGGAAGTCGAAATCTTGAGGGGCTGGAGCGCCAGAGGCAGATTCTGCTGGACGCCGCCGCCG
GCCTGCCGGCCGCGCCGCTTGAGATTCCGCTGACCCCATCGCGCGAGATCGACGCCAACGGTCGCGAGGCTGAGTTCCCG
CATCCGCCGTCGGTCGCCGTGATCGTCCGGCCGGAAGCGCCCGTCCAGGTGATCCTCACTGGTCACTACGACACCGTCTA
TCCCGAGAATAGCCCGTTCCAGGCCGTGAGCACCCGCTCGGACGGCGCGCTGCACGGTCCGGGCATCGCCGACATGAAGG
GCGGCATCTCGGTGATGCTGGCGGCTCTGGCGGCGTTCGAGACGCATCCGCACGCCGGCAATGTCGGCTACCGGGTCCTG
CTGTCGCCGGACGAGGAGATCGGGTCGATCGCATCAGGTCCGATCCTGTCTGAGTTCGCGCGTCAGGGACATGTCGGCCT
GACCTATGAACCCGCGCTGGCGGACGGGGCCCTGGCGGCCGCGCGCAAGGGGTCGGGCAATTTCCACATCGTCATCCACG
GGCGCGCGGCCCATGCCGGACGCGATTTCGCGGCGGGACGAAACGCGATCGTCGGCGCGGCGCGTATCGCCGAGAAGCTC
CACGCTTTGAATGGTTTGCGCGACGGTCTTACGGTGAACGTCGCGCGGATCGATGGCGGCGCGCCGCTGAACATGGTTCC
CGACGTCGCCGTCGTCCGTTTCAATGTCCGGTTCCCGGAGGCCGCTGCCGCTGTCTGGTTCGAGGCCGAGGTCGCGCGGA
TTGTGAGCGAAGTCGACCCCGACCTCCACGCCCACCTGCACGGCCTGATCACGCGCGGCGCCAAGCCGTTCAACGCCGCA
CAGCAGCAGCTGTTCGGCGCGGTGAAGGCTGTCGGGGCGCTGCTGGGCCAGCACATCACCTGGAAGCCGTCGGGGGGGGT
CTGCGAAGGCAATAATCTGTTCGCGTCCGGGCTTCCCAATGTCGATACGCTGGGCGTGCGTGGCGGCGATATCCATAGCG
AGGCCGAGCATGCCTGGCCCGAAAGCTTCGTCGAGCGCGCTCAGCTCTCGGCGAGCATCCTAATGAAGCTGGCCAGCGGG
GAGATCGACGCCAGAGCGATCCGCGCGGCCATGGAGAATGCGTGA

Upstream 100 bases:

>100_bases
CAAGCAAGGCTGTTGCGTGGGCCCCCGGTTACCTCGCTCGAGGTGAGCACGATTTGCCCGCGGCCCTTGGTTATCTTGAC
TGAGGGAGGAACGGCCTTTC

Downstream 100 bases:

>100_bases
ATGCTAGTCGTCCGTCCCGCCGGTTCCGCCGATTTTGAGGCCCTGATGGAGCTGGCCGTTCTGTCTGGGCGCGGCTTCAC
CAGTCTTCCCGAAGACGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MHLTSEDRSVLDRIAQDGGRIVDRAVDWCAINSGSRNLEGLERQRQILLDAAAGLPAAPLEIPLTPSREIDANGREAEFP
HPPSVAVIVRPEAPVQVILTGHYDTVYPENSPFQAVSTRSDGALHGPGIADMKGGISVMLAALAAFETHPHAGNVGYRVL
LSPDEEIGSIASGPILSEFARQGHVGLTYEPALADGALAAARKGSGNFHIVIHGRAAHAGRDFAAGRNAIVGAARIAEKL
HALNGLRDGLTVNVARIDGGAPLNMVPDVAVVRFNVRFPEAAAAVWFEAEVARIVSEVDPDLHAHLHGLITRGAKPFNAA
QQQLFGAVKAVGALLGQHITWKPSGGVCEGNNLFASGLPNVDTLGVRGGDIHSEAEHAWPESFVERAQLSASILMKLASG
EIDARAIRAAMENA

Sequences:

>Translated_414_residues
MHLTSEDRSVLDRIAQDGGRIVDRAVDWCAINSGSRNLEGLERQRQILLDAAAGLPAAPLEIPLTPSREIDANGREAEFP
HPPSVAVIVRPEAPVQVILTGHYDTVYPENSPFQAVSTRSDGALHGPGIADMKGGISVMLAALAAFETHPHAGNVGYRVL
LSPDEEIGSIASGPILSEFARQGHVGLTYEPALADGALAAARKGSGNFHIVIHGRAAHAGRDFAAGRNAIVGAARIAEKL
HALNGLRDGLTVNVARIDGGAPLNMVPDVAVVRFNVRFPEAAAAVWFEAEVARIVSEVDPDLHAHLHGLITRGAKPFNAA
QQQLFGAVKAVGALLGQHITWKPSGGVCEGNNLFASGLPNVDTLGVRGGDIHSEAEHAWPESFVERAQLSASILMKLASG
EIDARAIRAAMENA
>Mature_414_residues
MHLTSEDRSVLDRIAQDGGRIVDRAVDWCAINSGSRNLEGLERQRQILLDAAAGLPAAPLEIPLTPSREIDANGREAEFP
HPPSVAVIVRPEAPVQVILTGHYDTVYPENSPFQAVSTRSDGALHGPGIADMKGGISVMLAALAAFETHPHAGNVGYRVL
LSPDEEIGSIASGPILSEFARQGHVGLTYEPALADGALAAARKGSGNFHIVIHGRAAHAGRDFAAGRNAIVGAARIAEKL
HALNGLRDGLTVNVARIDGGAPLNMVPDVAVVRFNVRFPEAAAAVWFEAEVARIVSEVDPDLHAHLHGLITRGAKPFNAA
QQQLFGAVKAVGALLGQHITWKPSGGVCEGNNLFASGLPNVDTLGVRGGDIHSEAEHAWPESFVERAQLSASILMKLASG
EIDARAIRAAMENA

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 43570; Mature: 43570

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLTSEDRSVLDRIAQDGGRIVDRAVDWCAINSGSRNLEGLERQRQILLDAAAGLPAAPL
CCCCCHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCE
EIPLTPSREIDANGREAEFPHPPSVAVIVRPEAPVQVILTGHYDTVYPENSPFQAVSTRS
EECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCEECCCCCCCCEEECCC
DGALHGPGIADMKGGISVMLAALAAFETHPHAGNVGYRVLLSPDEEIGSIASGPILSEFA
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHCCCCCCHHHHHHH
RQGHVGLTYEPALADGALAAARKGSGNFHIVIHGRAAHAGRDFAAGRNAIVGAARIAEKL
HCCCCCEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHH
HALNGLRDGLTVNVARIDGGAPLNMVPDVAVVRFNVRFPEAAAAVWFEAEVARIVSEVDP
HHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
DLHAHLHGLITRGAKPFNAAQQQLFGAVKAVGALLGQHITWKPSGGVCEGNNLFASGLPN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEECCCCEEECCCCC
VDTLGVRGGDIHSEAEHAWPESFVERAQLSASILMKLASGEIDARAIRAAMENA
CCEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MHLTSEDRSVLDRIAQDGGRIVDRAVDWCAINSGSRNLEGLERQRQILLDAAAGLPAAPL
CCCCCHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCE
EIPLTPSREIDANGREAEFPHPPSVAVIVRPEAPVQVILTGHYDTVYPENSPFQAVSTRS
EECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCEECCCCCCCCEEECCC
DGALHGPGIADMKGGISVMLAALAAFETHPHAGNVGYRVLLSPDEEIGSIASGPILSEFA
CCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHCCCCCCHHHHHHH
RQGHVGLTYEPALADGALAAARKGSGNFHIVIHGRAAHAGRDFAAGRNAIVGAARIAEKL
HCCCCCEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHHHH
HALNGLRDGLTVNVARIDGGAPLNMVPDVAVVRFNVRFPEAAAAVWFEAEVARIVSEVDP
HHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
DLHAHLHGLITRGAKPFNAAQQQLFGAVKAVGALLGQHITWKPSGGVCEGNNLFASGLPN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEECCCCEEECCCCC
VDTLGVRGGDIHSEAEHAWPESFVERAQLSASILMKLASGEIDARAIRAAMENA
CCEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]