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The map label for this gene is kdpE [H]

Identifier: 16125842

GI number: 16125842

Start: 1763691

End: 1764464

Strand: Direct

Name: kdpE [H]

Synonym: CC_1595

Alternate gene names: 16125842

Gene position: 1763691-1764464 (Clockwise)

Preceding gene: 16125841

Following gene: 16125843

Centisome position: 43.91

GC content: 64.34

Gene sequence:

>774_bases
ATGGAAGGGGCACGCGGATTCTCATCAGCCTGCCCAAGACCGTCACGACGCCGCATCACCTGCTATGACGGAACCATGAG
CGCGCTTCGCCACCGCATCCTCGTCATCGACGATGAACCGCAAATCCATCGCTTCCTGGGACCGGCCCTTGATGCGGCCG
GCTATGAGGCCCTGCGCGCTGACAGCGGCCAGGAGGGCTTGCGCGGCATAGCGCTGTGGTCGCCCGACGCCGTGGTGCTG
GATCTGGGCTTGCCCGACATGGACGGCAAGGACGTGCTGGAGAAGGCGAGAGCCTTTTACGAAGGCCCGATCCTGATCCT
CTCCGCCCGGGATCGCGAGGTCGAGAAGATCGAGGCTCTGGATCGCGGGGCTAACGACTATGTGGAAAAGCCGTTCGGTG
TCGGCGAACTCCTGGCGCGCCTGCGCGTGGCGCTCAGGCAATCGGCAGCATCGAAACGGCCCACGGGGCCCCTGACCTTC
GGTGATGTGATCATCGATCTTGATCTGCGCCTGGTGACCAAGGCGGGCGCCGCCGTGAAGCTGTCGCCCAAAGAGTTCGA
ACTTCTCGCTCGCTTGGCGCTTTCGCCCGGCAAGGTGCTGACCCACAAGGAGCTTCTGGTCGGAATCTGGGGCGCCTCGC
ACGCGGACGACACTCAGTATCTGAGGGTGTTCGTGGGGCAGCTCCGGCAGAAGCTTGAGGACGACTCCGCGCATCCCAGA
TTGATCCTGACCGAACCTGGCGTAGGCTATCGGCTCCAGGGGGCGGCCAGCTAG

Upstream 100 bases:

>100_bases
CCCAGCGACCGCACTCAGGGGGCGGGCCTGGGGCTTTCGATCGCCAAGGGCTTCATCGACGCGCTGGGCGGACGTATCGC
CGCCGCCAGCCCGATTCACG

Downstream 100 bases:

>100_bases
CGGGCAGGGCTGACGTCGCCAAGACTACCGGCAGCCGGAGGCTAACCGCCTCTTGATGATGGCTATCAGGTAGCGTCAGT
GTGTCGCTGATCTCGGGCGT

Product: transcriptional regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MEGARGFSSACPRPSRRRITCYDGTMSALRHRILVIDDEPQIHRFLGPALDAAGYEALRADSGQEGLRGIALWSPDAVVL
DLGLPDMDGKDVLEKARAFYEGPILILSARDREVEKIEALDRGANDYVEKPFGVGELLARLRVALRQSAASKRPTGPLTF
GDVIIDLDLRLVTKAGAAVKLSPKEFELLARLALSPGKVLTHKELLVGIWGASHADDTQYLRVFVGQLRQKLEDDSAHPR
LILTEPGVGYRLQGAAS

Sequences:

>Translated_257_residues
MEGARGFSSACPRPSRRRITCYDGTMSALRHRILVIDDEPQIHRFLGPALDAAGYEALRADSGQEGLRGIALWSPDAVVL
DLGLPDMDGKDVLEKARAFYEGPILILSARDREVEKIEALDRGANDYVEKPFGVGELLARLRVALRQSAASKRPTGPLTF
GDVIIDLDLRLVTKAGAAVKLSPKEFELLARLALSPGKVLTHKELLVGIWGASHADDTQYLRVFVGQLRQKLEDDSAHPR
LILTEPGVGYRLQGAAS
>Mature_257_residues
MEGARGFSSACPRPSRRRITCYDGTMSALRHRILVIDDEPQIHRFLGPALDAAGYEALRADSGQEGLRGIALWSPDAVVL
DLGLPDMDGKDVLEKARAFYEGPILILSARDREVEKIEALDRGANDYVEKPFGVGELLARLRVALRQSAASKRPTGPLTF
GDVIIDLDLRLVTKAGAAVKLSPKEFELLARLALSPGKVLTHKELLVGIWGASHADDTQYLRVFVGQLRQKLEDDSAHPR
LILTEPGVGYRLQGAAS

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=46.8181818181818, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.9775784753363, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=35, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.5855855855856, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=30.9734513274336, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=31.2775330396476, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790552, Length=203, Percent_Identity=34.9753694581281, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=28.9592760180996, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=27.8260869565217, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=29.2035398230088, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=28.3842794759825, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=28.695652173913, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=28.3261802575107, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=35.15625, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=138, Percent_Identity=29.7101449275362, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28059; Mature: 28059

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGARGFSSACPRPSRRRITCYDGTMSALRHRILVIDDEPQIHRFLGPALDAAGYEALRA
CCCCCCCHHCCCCCCCCEEEEECCHHHHHCCEEEEECCCCHHHHHHHHHHHHCCHHHHHC
DSGQEGLRGIALWSPDAVVLDLGLPDMDGKDVLEKARAFYEGPILILSARDREVEKIEAL
CCCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
DRGANDYVEKPFGVGELLARLRVALRQSAASKRPTGPLTFGDVIIDLDLRLVTKAGAAVK
HCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEECCCCEEE
LSPKEFELLARLALSPGKVLTHKELLVGIWGASHADDTQYLRVFVGQLRQKLEDDSAHPR
ECHHHHHHHHHHHCCCCCEEEHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCE
LILTEPGVGYRLQGAAS
EEEECCCCCEEECCCCC
>Mature Secondary Structure
MEGARGFSSACPRPSRRRITCYDGTMSALRHRILVIDDEPQIHRFLGPALDAAGYEALRA
CCCCCCCHHCCCCCCCCEEEEECCHHHHHCCEEEEECCCCHHHHHHHHHHHHCCHHHHHC
DSGQEGLRGIALWSPDAVVLDLGLPDMDGKDVLEKARAFYEGPILILSARDREVEKIEAL
CCCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
DRGANDYVEKPFGVGELLARLRVALRQSAASKRPTGPLTFGDVIIDLDLRLVTKAGAAVK
HCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEECCCCEEE
LSPKEFELLARLALSPGKVLTHKELLVGIWGASHADDTQYLRVFVGQLRQKLEDDSAHPR
ECHHHHHHHHHHHCCCCCEEEHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCE
LILTEPGVGYRLQGAAS
EEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]