Click here to switch to the map view.

The map label for this gene is coaD

Identifier: 16125828

GI number: 16125828

Start: 1748114

End: 1748605

Strand: Direct

Name: coaD

Synonym: CC_1581

Alternate gene names: 16125828

Gene position: 1748114-1748605 (Clockwise)

Preceding gene: 16125827

Following gene: 16125829

Centisome position: 43.52

GC content: 63.62

Gene sequence:

>492_bases
ATGCGGGTCGGGCTTTATCCGGGGACCTTCGATCCGGTCACCAACGGTCACCTCGACATCATCGGGCGGGCCGTGAAGCT
GGTCGACAAGCTGGTGATCGGCGTCGCGATCAACATCGGCAAGGGCCCGCTGTTCTCTCTGGAGGAGCGGGTCGAGATCC
TCGAGCGCGAGACCGCGCACCTCAAGAAGATCGCCGAGATCGAGGTGCGGCCCTTCGACAGTCTGCTGATGCACTTCGCC
CGCGACGTGAACGCCCAGATGATCGTGCGCGGCCTGCGGGCCGTGGCCGACTTCGAGTACGAATTCCAGATGACGGCGAT
GAACCAGCAGCTGGATCGCGAAATCGAAACGGTGTTCCTGATGGCCGATCCGCGCCACCAGGCGATTGCTTCACGGCTGG
TGAAAGAAATCGCGACCCTCGGCGGCGACATCGGCAAGTTCGTGCCGCCCGGCGTGGCGCAGCAGTTGTTGGCCAAGGTC
GGAAAGGGCTAG

Upstream 100 bases:

>100_bases
GCGTCGAGCGCCTCGCCGATTCCGGCGGGGACGACAACCAGGGCGAGGACAGCGGGGCGGACGAGACCCCGTAACCCTCG
GAGCCAGAATAGGGGGTTGC

Downstream 100 bases:

>100_bases
AGCCCCTTCCTATCCGATAACTGTTTCACACTTATCGGAAAATGCTCCAGGCTTCGCCGTTATCCGGCCGAATTCCTGCG
CTTCAACGACCGTCGCACTT

Product: lipopolysaccharide core biosynthesis protein KdtB

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MRVGLYPGTFDPVTNGHLDIIGRAVKLVDKLVIGVAINIGKGPLFSLEERVEILERETAHLKKIAEIEVRPFDSLLMHFA
RDVNAQMIVRGLRAVADFEYEFQMTAMNQQLDREIETVFLMADPRHQAIASRLVKEIATLGGDIGKFVPPGVAQQLLAKV
GKG

Sequences:

>Translated_163_residues
MRVGLYPGTFDPVTNGHLDIIGRAVKLVDKLVIGVAINIGKGPLFSLEERVEILERETAHLKKIAEIEVRPFDSLLMHFA
RDVNAQMIVRGLRAVADFEYEFQMTAMNQQLDREIETVFLMADPRHQAIASRLVKEIATLGGDIGKFVPPGVAQQLLAKV
GKG
>Mature_163_residues
MRVGLYPGTFDPVTNGHLDIIGRAVKLVDKLVIGVAINIGKGPLFSLEERVEILERETAHLKKIAEIEVRPFDSLLMHFA
RDVNAQMIVRGLRAVADFEYEFQMTAMNQQLDREIETVFLMADPRHQAIASRLVKEIATLGGDIGKFVPPGVAQQLLAKV
GKG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=47.4683544303797, Blast_Score=160, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_CAUCN (B8GVE7)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002517025.1
- ProteinModelPortal:   B8GVE7
- SMR:   B8GVE7
- GeneID:   7331711
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01652
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18061; Mature: 18061

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGLYPGTFDPVTNGHLDIIGRAVKLVDKLVIGVAINIGKGPLFSLEERVEILERETAH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHH
LKKIAEIEVRPFDSLLMHFARDVNAQMIVRGLRAVADFEYEFQMTAMNQQLDREIETVFL
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEE
MADPRHQAIASRLVKEIATLGGDIGKFVPPGVAQQLLAKVGKG
EECCHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRVGLYPGTFDPVTNGHLDIIGRAVKLVDKLVIGVAINIGKGPLFSLEERVEILERETAH
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHH
LKKIAEIEVRPFDSLLMHFARDVNAQMIVRGLRAVADFEYEFQMTAMNQQLDREIETVFL
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEE
MADPRHQAIASRLVKEIATLGGDIGKFVPPGVAQQLLAKVGKG
EECCHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA