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The map label for this gene is mreB [H]

Identifier: 16125790

GI number: 16125790

Start: 1707341

End: 1708384

Strand: Direct

Name: mreB [H]

Synonym: CC_1543

Alternate gene names: 16125790

Gene position: 1707341-1708384 (Clockwise)

Preceding gene: 16125789

Following gene: 16125791

Centisome position: 42.5

GC content: 66.76

Gene sequence:

>1044_bases
ATGTTCTCTTCCCTTTTCGGCGTGATCTCGAACGACATCGCCATCGACCTCGGAACGGCCAACACCCTGATCTATCAGAA
GGGTAAGGGCATCGTGCTGAACGAGCCGTCGGTGGTGGCGCTACGCAATGTGGGCGGGCGCAAGGTCGTCCACGCCGTGG
GCATCGAGGCCAAGCAGATGCTGGGTCGTACGCCGGGTCACATGGAAGCCATCCGCCCGATGCGCGACGGCGTGATCGCC
GACTTCGAAGTCGCCGAAGAGATGATCAAGTATTTCATCCGCAAGGTTCACAACCGCAAGGGCTTCGTGAACCCCAAGGT
GATCGTGTGCGTGCCGTCGGGCGCCACCGCCGTGGAACGCCGCGCCATCAACGACAGCTGCCTGAACGCCGGCGCGCGCC
GCGTGGGCCTGATCGACGAGCCGATGGCCGCCGCGATCGGCGCTGGCCTGCCGATCCACGAGCCGACCGGCTCGATGGTC
GTCGACATCGGCGGCGGCACCACCGAGGTGGCCGTGCTGTCGCTGTCGGGCATCGTCTATTCGCGCAGCGTCCGCGTCGG
CGGCGACAAGATGGACGAGGCGATCATCAGCTATATGCGTCGCCACCATAACCTGCTGATCGGCGAGACGACCGCCGAGC
GCATCAAGAAGGAAATCGGCACCGCCCGCGCGCCGGCCGACGGCGAAGGTCTGTCGATCGACGTCAAGGGCCGCGACCTG
ATGCAGGGCGTGCCGCGCGAAGTCCGCATCAGCGAAAAGCAGGCCGCCGACGCTCTGGCCGAACCGGTCGGGCAGATCGT
CGAGGCCGTGAAGGTCGCCCTGGAGGCCACGCCGCCGGAACTGGCCAGCGACATCGCCGACAAGGGCATCATGCTGACGG
GCGGCGGCGCGCTGCTGCGCGGCCTGGATGCCGAGATCCGCGATCATACCGGCCTGCCGGTCACGGTCGCCGACGATCCG
CTCTCGTGCGTGGCCCTGGGCTGCGGCAAGGTGCTGGAACATCCCAAGTGGATGAAGGGCGTCCTGGAATCCACGCTGGC
CTAG

Upstream 100 bases:

>100_bases
CCGACCCCGTCTTCAGAGATGGATTTGGCCCTTCTTCTACGATCTGCCCCTCGATCCGACCGCTCGTTACGCCCCTCCTA
CCCCTCAGTCAGGGCTTTCA

Downstream 100 bases:

>100_bases
GCCGGTATTCCTTATAGAAGCGCCGCGGGGGGCGTCGGGAGAAACTTAAGTGCGCTTTCGTGAAGGTCCGCTGGGCGACC
TGAAGGTGCCATTGACGTGG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFSSLFGVISNDIAIDLGTANTLIYQKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQMLGRTPGHMEAIRPMRDGVIA
DFEVAEEMIKYFIRKVHNRKGFVNPKVIVCVPSGATAVERRAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGSMV
VDIGGGTTEVAVLSLSGIVYSRSVRVGGDKMDEAIISYMRRHHNLLIGETTAERIKKEIGTARAPADGEGLSIDVKGRDL
MQGVPREVRISEKQAADALAEPVGQIVEAVKVALEATPPELASDIADKGIMLTGGGALLRGLDAEIRDHTGLPVTVADDP
LSCVALGCGKVLEHPKWMKGVLESTLA

Sequences:

>Translated_347_residues
MFSSLFGVISNDIAIDLGTANTLIYQKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQMLGRTPGHMEAIRPMRDGVIA
DFEVAEEMIKYFIRKVHNRKGFVNPKVIVCVPSGATAVERRAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGSMV
VDIGGGTTEVAVLSLSGIVYSRSVRVGGDKMDEAIISYMRRHHNLLIGETTAERIKKEIGTARAPADGEGLSIDVKGRDL
MQGVPREVRISEKQAADALAEPVGQIVEAVKVALEATPPELASDIADKGIMLTGGGALLRGLDAEIRDHTGLPVTVADDP
LSCVALGCGKVLEHPKWMKGVLESTLA
>Mature_347_residues
MFSSLFGVISNDIAIDLGTANTLIYQKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQMLGRTPGHMEAIRPMRDGVIA
DFEVAEEMIKYFIRKVHNRKGFVNPKVIVCVPSGATAVERRAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGSMV
VDIGGGTTEVAVLSLSGIVYSRSVRVGGDKMDEAIISYMRRHHNLLIGETTAERIKKEIGTARAPADGEGLSIDVKGRDL
MQGVPREVRISEKQAADALAEPVGQIVEAVKVALEATPPELASDIADKGIMLTGGGALLRGLDAEIRDHTGLPVTVADDP
LSCVALGCGKVLEHPKWMKGVLESTLA

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=337, Percent_Identity=63.5014836795252, Blast_Score=404, Evalue=1e-114,
Organism=Escherichia coli, GI1788875, Length=366, Percent_Identity=23.7704918032787, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36685; Mature: 36685

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSSLFGVISNDIAIDLGTANTLIYQKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQM
CCHHHHHHHCCCEEEEECCCCEEEEECCCEEEECCCCEEEEECCCCCEEHHHHCCHHHHH
LGRTPGHMEAIRPMRDGVIADFEVAEEMIKYFIRKVHNRKGFVNPKVIVCVPSGATAVER
HCCCCCHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHH
RAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGSMVVDIGGGTTEVAVLSLSGIVY
HHCCHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEEECCCEE
SRSVRVGGDKMDEAIISYMRRHHNLLIGETTAERIKKEIGTARAPADGEGLSIDVKGRDL
ECEEECCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCCCCCCCCCCCEEEECCCHH
MQGVPREVRISEKQAADALAEPVGQIVEAVKVALEATPPELASDIADKGIMLTGGGALLR
HHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCHHHHH
GLDAEIRDHTGLPVTVADDPLSCVALGCGKVLEHPKWMKGVLESTLA
CCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MFSSLFGVISNDIAIDLGTANTLIYQKGKGIVLNEPSVVALRNVGGRKVVHAVGIEAKQM
CCHHHHHHHCCCEEEEECCCCEEEEECCCEEEECCCCEEEEECCCCCEEHHHHCCHHHHH
LGRTPGHMEAIRPMRDGVIADFEVAEEMIKYFIRKVHNRKGFVNPKVIVCVPSGATAVER
HCCCCCHHHHHHHHHCCCEECHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHH
RAINDSCLNAGARRVGLIDEPMAAAIGAGLPIHEPTGSMVVDIGGGTTEVAVLSLSGIVY
HHCCHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCEEEEEEECCCEE
SRSVRVGGDKMDEAIISYMRRHHNLLIGETTAERIKKEIGTARAPADGEGLSIDVKGRDL
ECEEECCCCHHHHHHHHHHHHHCCEEEECHHHHHHHHHHCCCCCCCCCCCCEEEECCCHH
MQGVPREVRISEKQAADALAEPVGQIVEAVKVALEATPPELASDIADKGIMLTGGGALLR
HHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCHHHHH
GLDAEIRDHTGLPVTVADDPLSCVALGCGKVLEHPKWMKGVLESTLA
CCCCHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]