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The map label for this gene is argC

Identifier: 16125627

GI number: 16125627

Start: 1527932

End: 1528885

Strand: Direct

Name: argC

Synonym: CC_1378

Alternate gene names: 16125627

Gene position: 1527932-1528885 (Clockwise)

Preceding gene: 16125626

Following gene: 16125630

Centisome position: 38.04

GC content: 67.71

Gene sequence:

>954_bases
ATGGCGAACGCTCCCAAGGTCTTCATCGACGGCGAAGCCGGCACCACCGGCCTGCAGATTCGTGAGCGTCTGGTCGGTCG
CACCGATCTGCAGCTGATCTCGATCGATCCGGACAAGCGCAAGGACGCCGACGCACGCGCCGAGATGCTGAACAGCGCCG
ACGCGGTGATCCTGTGCCTGCCCGATGACGCGGCCAAGGAAGCCGTCTCTCTGGTCAGCAATCCGAACACGGTGATCATC
GACGCCTCGACCGCCTATCGCACGGCCGAGGGCTGGGCCTACGGCTTTGCGGAGCTCGACAGCGAGCAGCGCGGCAAGAT
CGCGGCCTCCAAGCGGATCTCCAATCCCGGCTGCTATCCGACCGGCGCAATCGCCCTGACGCGGCCACTGGTCAGCGCCG
GCATCCTGCCGGCCGAGCTGCCGGTCTCGTACAACGCCGTCTCGGGCTATACCGGCGGCGGCAAGGCGATGATCGCCCAG
TTCGAGGATGAGAGCGCCGCCGACCACACCCGGGCGCCGTACTTCATCTACGGCCTCTCGCTGAGCCACAAGCACGTGCC
GGAAATGCAGAAGCACGGCGGTCTGCTGACCCGTCCGATCTTCACGCCCGCCGTCGGCCGCTACGCCCAGGGCATGATCG
TCGAGATGCCGCTGCATCTCTCGACCCTGAATGGCGCGCCGTCGCTGGCCGACATCCATGCGGCGCTGGTCAAGCACTAC
AAGGGCGAGGCGTTCGTCGAGGTCGCGTCGCTGGACGAGGCCAAGGCGCTGACGACCCTGGACCCCGAGGGCCTGAACGG
CACGAACCGCCTCAAGCTCTTCGTGTTCGGCTCGGACGCCGGAGGCCAGGCGCGTCTGGTGGCGCTGCTCGACAACCTCG
GCAAGGGCGCGTCCGGCGCGGCGGTGCAGAACCTGAACATCGCGCTCGGGCTGGATGAGGCCGCAGGCCTGTAG

Upstream 100 bases:

>100_bases
AAGCGCTAATCGCGACGATTACGTGTTTGGGAAGGGGCGCTTCGGTTCAGCCGAAGCGCCCTTTTTCTTGTCCTGTCTCT
TGTTCGGATTGGAGTCCGCC

Downstream 100 bases:

>100_bases
ACCTGTCTCAGACCCGCCAGCGGTAGTGGCCGGCGGGTTTGTGCAGCTTGAAGCGCCACAGCGGCTCTTCCCTGACGCCA
TCGCCGACATTGTGCGCCAC

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MANAPKVFIDGEAGTTGLQIRERLVGRTDLQLISIDPDKRKDADARAEMLNSADAVILCLPDDAAKEAVSLVSNPNTVII
DASTAYRTAEGWAYGFAELDSEQRGKIAASKRISNPGCYPTGAIALTRPLVSAGILPAELPVSYNAVSGYTGGGKAMIAQ
FEDESAADHTRAPYFIYGLSLSHKHVPEMQKHGGLLTRPIFTPAVGRYAQGMIVEMPLHLSTLNGAPSLADIHAALVKHY
KGEAFVEVASLDEAKALTTLDPEGLNGTNRLKLFVFGSDAGGQARLVALLDNLGKGASGAAVQNLNIALGLDEAAGL

Sequences:

>Translated_317_residues
MANAPKVFIDGEAGTTGLQIRERLVGRTDLQLISIDPDKRKDADARAEMLNSADAVILCLPDDAAKEAVSLVSNPNTVII
DASTAYRTAEGWAYGFAELDSEQRGKIAASKRISNPGCYPTGAIALTRPLVSAGILPAELPVSYNAVSGYTGGGKAMIAQ
FEDESAADHTRAPYFIYGLSLSHKHVPEMQKHGGLLTRPIFTPAVGRYAQGMIVEMPLHLSTLNGAPSLADIHAALVKHY
KGEAFVEVASLDEAKALTTLDPEGLNGTNRLKLFVFGSDAGGQARLVALLDNLGKGASGAAVQNLNIALGLDEAAGL
>Mature_316_residues
ANAPKVFIDGEAGTTGLQIRERLVGRTDLQLISIDPDKRKDADARAEMLNSADAVILCLPDDAAKEAVSLVSNPNTVIID
ASTAYRTAEGWAYGFAELDSEQRGKIAASKRISNPGCYPTGAIALTRPLVSAGILPAELPVSYNAVSGYTGGGKAMIAQF
EDESAADHTRAPYFIYGLSLSHKHVPEMQKHGGLLTRPIFTPAVGRYAQGMIVEMPLHLSTLNGAPSLADIHAALVKHYK
GEAFVEVASLDEAKALTTLDPEGLNGTNRLKLFVFGSDAGGQARLVALLDNLGKGASGAAVQNLNIALGLDEAAGL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=236, Percent_Identity=30.5084745762712, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320913, Length=282, Percent_Identity=29.4326241134752, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_CAUCN (B8H555)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002516815.1
- ProteinModelPortal:   B8H555
- GeneID:   7330172
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_01442
- OMA:   PIFVPSV
- ProtClustDB:   PRK11863
- GO:   GO:0005737
- HAMAP:   MF_01110
- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01851

Pfam domain/function: PF01118 Semialdhyde_dh

EC number: =1.2.1.38

Molecular weight: Translated: 33278; Mature: 33147

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANAPKVFIDGEAGTTGLQIRERLVGRTDLQLISIDPDKRKDADARAEMLNSADAVILCL
CCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEC
PDDAAKEAVSLVSNPNTVIIDASTAYRTAEGWAYGFAELDSEQRGKIAASKRISNPGCYP
CCHHHHHHHHHHCCCCEEEEECCCCEECCCCCEEEHHHCCCCCCCCCHHHHCCCCCCCCC
TGAIALTRPLVSAGILPAELPVSYNAVSGYTGGGKAMIAQFEDESAADHTRAPYFIYGLS
CCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEC
LSHKHVPEMQKHGGLLTRPIFTPAVGRYAQGMIVEMPLHLSTLNGAPSLADIHAALVKHY
CCCCCCCHHHHCCCEEECCCCCHHHHHHHCCEEEEECEEEEECCCCCCHHHHHHHHHHHC
KGEAFVEVASLDEAKALTTLDPEGLNGTNRLKLFVFGSDAGGQARLVALLDNLGKGASGA
CCCEEEEEECCCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCEEHEEEHHHCCCCCCCC
AVQNLNIALGLDEAAGL
EEEEEEEEEECHHHCCC
>Mature Secondary Structure 
ANAPKVFIDGEAGTTGLQIRERLVGRTDLQLISIDPDKRKDADARAEMLNSADAVILCL
CCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCEEEEEC
PDDAAKEAVSLVSNPNTVIIDASTAYRTAEGWAYGFAELDSEQRGKIAASKRISNPGCYP
CCHHHHHHHHHHCCCCEEEEECCCCEECCCCCEEEHHHCCCCCCCCCHHHHCCCCCCCCC
TGAIALTRPLVSAGILPAELPVSYNAVSGYTGGGKAMIAQFEDESAADHTRAPYFIYGLS
CCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEC
LSHKHVPEMQKHGGLLTRPIFTPAVGRYAQGMIVEMPLHLSTLNGAPSLADIHAALVKHY
CCCCCCCHHHHCCCEEECCCCCHHHHHHHCCEEEEECEEEEECCCCCCHHHHHHHHHHHC
KGEAFVEVASLDEAKALTTLDPEGLNGTNRLKLFVFGSDAGGQARLVALLDNLGKGASGA
CCCEEEEEECCCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCEEHEEEHHHCCCCCCCC
AVQNLNIALGLDEAAGL
EEEEEEEEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA