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The map label for this gene is gfo [H]

Identifier: 16125475

GI number: 16125475

Start: 1383695

End: 1384795

Strand: Direct

Name: gfo [H]

Synonym: CC_1225

Alternate gene names: 16125475

Gene position: 1383695-1384795 (Clockwise)

Preceding gene: 16125474

Following gene: 16125476

Centisome position: 34.45

GC content: 66.76

Gene sequence:

>1101_bases
ATGGAAACGATCAGCAAGAGAAGCCTTCTCGCCGCGGGTCTGGCGGCCGGCGTCGCCGGACTGCCGCGCGGCGCCTTCGC
CGCTCAGCCGGGCCGCAAGCTGGGCTATGCGATCCTGGGCCTGGGCTACTACGCCACGCGCATCATCATGCCGCGCTTTG
CCGAGTGCGAGCACTCGCGCCTAGCCGCCCTGGTCAGCGGTACGCCCGAAAAGCTGAAAACCTACGGCGAGCAGTACGGG
ATCCCCGAGACGCACCGCTACAGCTACGAGACCTTCGACCGGATCATCGATAATCCCGATGTCGACATCGTCTATGTGAT
CACGCCCAACAGCCTCCACCGCCCCTTCACCGAGCGGGCCGCCAGGGCCGGCAAGCACGTGATGTGCGAAAAGCCGATGG
CGAACACGGTCGCCGACTGCGAGGCGATGATCGCCGCCTGCAAGAAGGCCGGCCGCAAGCTGATGATCGGCTATCGCAGC
CGCTTCCAGGCCCACAATATCGAAGCGATCAAGCTGGTGCGCGACGGCGCGCTGGGACCGGTGCGCACGGTGGTCACCGA
TCACGGCTTCACGATCGGCGATCCCAAGCAGTGGCGTTTGAACAGGGCGCTGGCCGGCGGCGGCAGCCTGATGGACATCG
GCATCTACAGCCTGAACGCCGCGCGCTATCTCACGGGCGAGGAGCCTGTGGCCGTCAACGCCGTGGAGTCCACGGACCGA
TCCGATCCGCGCTTCGGTGAGGTGGAGGACATCATCAACTTCCAGCTCCTCTTCCCATCCGGCGCCACGGCCAACTGCGT
GTCGGCCTACAGCGTCAACTGCAACCGCTATCGGGTGAGCGGGCCCAAGGGCTGGGTCGAGATCGACCCGGCGACCAGCT
ATCAGGGCCAGGCCATGCGGGCGCAGCTTGGCGGTCCGCCCGCGCCGCGTGAACCGGCGCCGCAGCCCAAGAACCAGTTC
TCGGCCCAGCTGGATCACCTGTCCGAGTGCATCCTCACCGGCCGCGAGCCGATCGTCGGCGGGGACGATGGCCTCAAGGA
CCTCCGAGTGATCGAAGCGATCTACCGCGCGGCGCGAGAAGGGCGGACGGTCAAGCTGTGA

Upstream 100 bases:

>100_bases
CCAATTGCGTATTCGGCGAGGACGGCGGGACGCTGTTCATCACCTCCAACCATCTCGTGGCGCGGGTGCGCACCAAGACC
AAAGGGCTGGGGCGCTAGCG

Downstream 100 bases:

>100_bases
GGGCGCTCCTCCTGATCGCCGCTCTGCTGGCCCCGACGGCGGCGTTGGCGCAGCAGCAGCTCCCGCTATGGCCCAACGGC
GCGCCGGGTTTCGAGAGCCG

Product: glucose-fructose oxidoreductase

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
METISKRSLLAAGLAAGVAGLPRGAFAAQPGRKLGYAILGLGYYATRIIMPRFAECEHSRLAALVSGTPEKLKTYGEQYG
IPETHRYSYETFDRIIDNPDVDIVYVITPNSLHRPFTERAARAGKHVMCEKPMANTVADCEAMIAACKKAGRKLMIGYRS
RFQAHNIEAIKLVRDGALGPVRTVVTDHGFTIGDPKQWRLNRALAGGGSLMDIGIYSLNAARYLTGEEPVAVNAVESTDR
SDPRFGEVEDIINFQLLFPSGATANCVSAYSVNCNRYRVSGPKGWVEIDPATSYQGQAMRAQLGGPPAPREPAPQPKNQF
SAQLDHLSECILTGREPIVGGDDGLKDLRVIEAIYRAAREGRTVKL

Sequences:

>Translated_366_residues
METISKRSLLAAGLAAGVAGLPRGAFAAQPGRKLGYAILGLGYYATRIIMPRFAECEHSRLAALVSGTPEKLKTYGEQYG
IPETHRYSYETFDRIIDNPDVDIVYVITPNSLHRPFTERAARAGKHVMCEKPMANTVADCEAMIAACKKAGRKLMIGYRS
RFQAHNIEAIKLVRDGALGPVRTVVTDHGFTIGDPKQWRLNRALAGGGSLMDIGIYSLNAARYLTGEEPVAVNAVESTDR
SDPRFGEVEDIINFQLLFPSGATANCVSAYSVNCNRYRVSGPKGWVEIDPATSYQGQAMRAQLGGPPAPREPAPQPKNQF
SAQLDHLSECILTGREPIVGGDDGLKDLRVIEAIYRAAREGRTVKL
>Mature_366_residues
METISKRSLLAAGLAAGVAGLPRGAFAAQPGRKLGYAILGLGYYATRIIMPRFAECEHSRLAALVSGTPEKLKTYGEQYG
IPETHRYSYETFDRIIDNPDVDIVYVITPNSLHRPFTERAARAGKHVMCEKPMANTVADCEAMIAACKKAGRKLMIGYRS
RFQAHNIEAIKLVRDGALGPVRTVVTDHGFTIGDPKQWRLNRALAGGGSLMDIGIYSLNAARYLTGEEPVAVNAVESTDR
SDPRFGEVEDIINFQLLFPSGATANCVSAYSVNCNRYRVSGPKGWVEIDPATSYQGQAMRAQLGGPPAPREPAPQPKNQF
SAQLDHLSECILTGREPIVGGDDGLKDLRVIEAIYRAAREGRTVKL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=310, Percent_Identity=23.5483870967742, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI87082405, Length=261, Percent_Identity=30.2681992337165, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787574, Length=373, Percent_Identity=26.0053619302949, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081947, Length=144, Percent_Identity=25.6944444444444, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789848, Length=331, Percent_Identity=23.2628398791541, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581117, Length=242, Percent_Identity=26.0330578512397, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24581115, Length=252, Percent_Identity=27.3809523809524, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 39852; Mature: 39852

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METISKRSLLAAGLAAGVAGLPRGAFAAQPGRKLGYAILGLGYYATRIIMPRFAECEHSR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCHHHH
LAALVSGTPEKLKTYGEQYGIPETHRYSYETFDRIIDNPDVDIVYVITPNSLHRPFTERA
HHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCHHHHH
ARAGKHVMCEKPMANTVADCEAMIAACKKAGRKLMIGYRSRFQAHNIEAIKLVRDGALGP
HHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCEEEEEECCCCCCC
VRTVVTDHGFTIGDPKQWRLNRALAGGGSLMDIGIYSLNAARYLTGEEPVAVNAVESTDR
HHHHHCCCCEECCCCHHHHHHHHHCCCCCEEEEEEEEECCEEEECCCCCEEEEEECCCCC
SDPRFGEVEDIINFQLLFPSGATANCVSAYSVNCNRYRVSGPKGWVEIDPATSYQGQAMR
CCCCCCCHHHHEEEEEECCCCCCCCCEEEEEECCCEEEECCCCCCEEECCCCCCCCCHHH
AQLGGPPAPREPAPQPKNQFSAQLDHLSECILTGREPIVGGDDGLKDLRVIEAIYRAARE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GRTVKL
CCEECC
>Mature Secondary Structure
METISKRSLLAAGLAAGVAGLPRGAFAAQPGRKLGYAILGLGYYATRIIMPRFAECEHSR
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHCHHHH
LAALVSGTPEKLKTYGEQYGIPETHRYSYETFDRIIDNPDVDIVYVITPNSLHRPFTERA
HHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEECCCHHCCCHHHHH
ARAGKHVMCEKPMANTVADCEAMIAACKKAGRKLMIGYRSRFQAHNIEAIKLVRDGALGP
HHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCCEEEEEECCCCCCC
VRTVVTDHGFTIGDPKQWRLNRALAGGGSLMDIGIYSLNAARYLTGEEPVAVNAVESTDR
HHHHHCCCCEECCCCHHHHHHHHHCCCCCEEEEEEEEECCEEEECCCCCEEEEEECCCCC
SDPRFGEVEDIINFQLLFPSGATANCVSAYSVNCNRYRVSGPKGWVEIDPATSYQGQAMR
CCCCCCCHHHHEEEEEECCCCCCCCCEEEEEECCCEEEECCCCCCEEECCCCCCCCCHHH
AQLGGPPAPREPAPQPKNQFSAQLDHLSECILTGREPIVGGDDGLKDLRVIEAIYRAARE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GRTVKL
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]