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The map label for this gene is rnz [H]

Identifier: 16125428

GI number: 16125428

Start: 1335410

End: 1336363

Strand: Direct

Name: rnz [H]

Synonym: CC_1176

Alternate gene names: 16125428

Gene position: 1335410-1336363 (Clockwise)

Preceding gene: 16125426

Following gene: 16125429

Centisome position: 33.24

GC content: 67.71

Gene sequence:

>954_bases
ATGCAGGATCTGCCCGACGGCCTGCATGTGGGCCTCTGCGGCGCGGGCTCACCCATGGCTGACCCGCTGCGGTCGGGACC
CTGTGTGGCGGTGGTCGCGGGCAAGGACCTGTTCGTCGTCGACTCCGGGTCAGGCTCGACCCGCAATCTGCTCCTGATGA
ACATGCCGCCGCCGCGGGTCAGCGCGGTGTTCATCACCCACTACCACTCCGACCACATCGCCGATCTTGGCGAGCTGATG
TTGCAGCGCTGGGCGGGCGGCGCCTCGAAGACCCCGACGCCGGTCTATGGTCCGCAAGGGCTGGAGCAGGTCGTTCAGGG
CTTCGAGCAGGCCTATACGCTGGATCGCGGCTATCGCATCGCCCACCACGGCGAGGCCGTCGCGCCGCCGTCGGGCTTTG
GCGGCGATCCGCGCCCGTTCGTGGCTGACCCGGCGGCGCCGGATGTCCTGGTGCTGGAGAAGCCTGGCCTGAAGGTCTGG
GCCTTCCCCGTGGCGCACCATCCGGTCGAGGGCGCGGTCGGCTATCGGTTCGAATACAAGGGCCGCAGCGTCGTGATCAG
CGGCGACACCGGGCCGTCGGAGCGCCTGGTGAAGGCGTCCAAGGGCGCGGATCTGTTGTTGCATGAGGGCCTGGCCCCGA
ACCTCGTCGCGGTCCAGAAAGATGTTGCGGACAAGATGGGGCGCGACAACTACGCCAAGATCTTCCACGACATTCTCGAC
TACCACACCGCGCCGGAAGTTGCGGCCGAGGAGGCCAAGGCGGCGGGCGTCGGGGCGCTGATGTTCTATCACATCATCCC
GCCGCTGCCGGTGCGCGCGCTGGATGGTCCGTTTCTGGGCCGCTCGCGAGAGATCTTCGACGGGCCGATCAAGGTGGGCC
GCGATGGCGACTTCGCCTCGTTGCCGGTCGGCTCGAAAGAGATCAAGTGGTCCAACCGCTTGCTCGCCCTCTAG

Upstream 100 bases:

>100_bases
CGTGATCGCTGTGGGTCTTGGGACCGCCTGGCTGATGCGCGAGCGTCTGGCGCAGGCGGCCATGCGCAAGGTCTATGAGC
AGGTCCTGGCCGTCGACACG

Downstream 100 bases:

>100_bases
ATTGGACTTGGCCCCGCGCCGGTCGCGGAGCTAAGCAGGGCGGAACACAGGGAGGTCCCGTTCGTGAGTTCCGCGCCGCG
CTATCTTCAAGCGGGGGCCG

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MQDLPDGLHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRVSAVFITHYHSDHIADLGELM
LQRWAGGASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRIAHHGEAVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVW
AFPVAHHPVEGAVGYRFEYKGRSVVISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILD
YHTAPEVAAEEAKAAGVGALMFYHIIPPLPVRALDGPFLGRSREIFDGPIKVGRDGDFASLPVGSKEIKWSNRLLAL

Sequences:

>Translated_317_residues
MQDLPDGLHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRVSAVFITHYHSDHIADLGELM
LQRWAGGASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRIAHHGEAVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVW
AFPVAHHPVEGAVGYRFEYKGRSVVISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILD
YHTAPEVAAEEAKAAGVGALMFYHIIPPLPVRALDGPFLGRSREIFDGPIKVGRDGDFASLPVGSKEIKWSNRLLAL
>Mature_317_residues
MQDLPDGLHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRVSAVFITHYHSDHIADLGELM
LQRWAGGASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRIAHHGEAVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVW
AFPVAHHPVEGAVGYRFEYKGRSVVISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILD
YHTAPEVAAEEAKAAGVGALMFYHIIPPLPVRALDGPFLGRSREIFDGPIKVGRDGDFASLPVGSKEIKWSNRLLAL

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 33787; Mature: 33787

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLPDGLHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRV
CCCCCCCCEEEEECCCCCCCCHHCCCCEEEEEECCEEEEEECCCCCCCEEEEEECCCCCE
SAVFITHYHSDHIADLGELMLQRWAGGASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRI
EEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
AHHGEAVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVWAFPVAHHPVEGAVGYRFEYK
EECCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEEEC
GRSVVISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILD
CCEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
YHTAPEVAAEEAKAAGVGALMFYHIIPPLPVRALDGPFLGRSREIFDGPIKVGRDGDFAS
HCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEE
LPVGSKEIKWSNRLLAL
CCCCCCCCCCCCCEECC
>Mature Secondary Structure
MQDLPDGLHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRV
CCCCCCCCEEEEECCCCCCCCHHCCCCEEEEEECCEEEEEECCCCCCCEEEEEECCCCCE
SAVFITHYHSDHIADLGELMLQRWAGGASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRI
EEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEE
AHHGEAVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVWAFPVAHHPVEGAVGYRFEYK
EECCCCCCCCCCCCCCCCCCEECCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEEEC
GRSVVISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILD
CCEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
YHTAPEVAAEEAKAAGVGALMFYHIIPPLPVRALDGPFLGRSREIFDGPIKVGRDGDFAS
HCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEE
LPVGSKEIKWSNRLLAL
CCCCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]