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The map label for this gene is 16125359

Identifier: 16125359

GI number: 16125359

Start: 1254206

End: 1256224

Strand: Direct

Name: 16125359

Synonym: CC_1107

Alternate gene names: NA

Gene position: 1254206-1256224 (Clockwise)

Preceding gene: 16125358

Following gene: 16125360

Centisome position: 31.22

GC content: 66.82

Gene sequence:

>2019_bases
ATGGCTGACCTCGACACCCTGGAAATGCTCAGCAAGCTGACCGCAGACGGCTGTTCGCTGGGCGATGTGATCACCCTGGC
CAGCAACCTGGCGACCGGCGGCCAACCGGCGCTTGCGGACCAGGCCTACAAGATCTGGATCAAGTTCAACCCAGACCATC
CGCAGCTCTGCGTGGCCCTGTTCAACCGCTCGGTTCTCCAGGCCGCACTCGGCGACAGTGTCGCCGCCGCCGCCTCGCTG
GAGCAGGCTATTCAGATCAATCCCGAGTTCATGCCCGCCTATGTCAATCTGGGCGGGCTCCAGGAACGCGCCGGCCTGCA
AGAGCTGGCGATCGCGACCTGGGAGGCCGGAGCCAATCGGCCGATCGTCTTGAACGGCATGGGAGTCAGCTACGCCTTCA
CCTGCCTCAAGCAGATCGCGCGCTTGCTGGGCGAGATGCACCAGCCCGCCCGGGCGGAACTGGCCTTGCAGCGGGCGGCG
GATATCGATCCGAAGGCCATGGACGTCATCGGCCAGCTGGTCGCCACGCGCCTGTCGCAATGCAAATGGCCCGCCGTGCA
GCCGACCGAGCGCCTGAGCCGCGAAACGCTGCTGAATGGGGTCAATCCGCTGTCGATCGCGGCCTATTCCGACGATCCGC
TTCTGCAGCTGGGCGCGGCCAATCAGTTCATCGAGCGCGAAGCCAAGACCACGCCGGAGCAAGTCCGTGCCGATCGCCGC
GATGCGCCGATCGACTTGGCGGGGCGCCGCCCCCGGATCGGCTATATCTCGTCCGACCTGCGCGACCACGCGGTCGGCTA
CCTGATGGCCGAGCTCTTCGAGGTGCACGACAAGGCCAAGGTCGAGGTGTTCGCCTACTATTGCGGCCCGGAGTCCAGCG
ATGGCCTGAACACGCGCATCCGGGCGGCGGCCGAGCACTTCATCGATATTCGCCCCATGAGCGACGACGAGGCCGCCCAG
CGCATCGTCGACGACGGCATCGACATCCTGGTAGACGTCAACGGCCACACCCGTGACGCCCGCACCGCCGTCTTCGCCCG
CCGCCCCGCGCCGATCCTGGTCAACTGGCTGGGCTATCCCGGCACGATGGGCAGCGACTACCACCACTACATTGTCGGCG
ATCCGTGGATCATCCCGCCGGAGATGGAGCTCTACTACTCGGAGGCCGTTCGCCGGATTCCCTGCTACCAGCCGAATGAC
CGGCGACGCATCGTGGCCAGCGACGTCCCGACGCGGACCGAGGCGGGCCTACCCGAAGACGGCTTCGTCTTCTGCTGCTT
CAACGGCACGCAGAAGATCACCCCGCACGTCTTCGACCGCTGGATGGAGATTCTCAAGCGCACATCTGGCAGCGTGCTGT
GGCTGCTGGACAGCAATCCGGAGACCAACGCCCGCCTGCGCGACGCCGCCGAGGCGCGGGGCGTTGACCGCATGCGTCTG
GTCTTCGCGCCCAAGATGCCCAACGCCTTCCATCTGGCGCGCTATCGCCTGGCGGACCTGTTCCTGGACACCACGCCCTA
CGGCGCCCACACGACGGCTTCCGACGCGCTCTGGATGGCCGTGCCGGTCCTGACCTGGTCGGGCCGCTCGTTCGCCTCGC
GGGTCTGCGGCAGCTTGGTGCGCAGCGCCGGCCTTCCCGAACTGGTCGTGGATAGCGCCGCAGCCTATGTCGAAAAGGCC
GTCGAGATCGGTTCGGATCGTGCGCGCGCCCAGGCCTTGCGCGCCACGCTGGAGGCCAATCGCGACACCTGCGTGCTGTT
TGACATGGACCTGTTGGCCGACAAGCTTGAGACGCTCTACGGCGAGATGATCGCTGAGTATCAGGCGGGCCTGCGTCCGC
AACCGAACCTCGCCAATCTGGCGACCTATCTCGCGGTGGGTCTCGCCTTGGATCGGGACGAGCGCGAGGCGCAAGCTGAA
CCGGATCTGCATGGCGTCTATCGCCGCGAGCTGGCGCGGCGGCACGCCGTAAAGGCCATCGCGCCTGATGCCCGCCTGTG
GGAGGGCCAGGGCCGGTGA

Upstream 100 bases:

>100_bases
CGATGGTCGAGTTTCCGCCCCCATGCCATGATCGCGTTCGGTCGACTCGCGCGCCGCGTTCGCTTGCGCCTGTCCGCCGC
CCCTCGGTTTCAGGAAGACA

Downstream 100 bases:

>100_bases
ACCGCGAGCAACTGCAGGCCCTGAAGCTGGACGGCTACGCGCCGCGCACCATGCTGGACATCGGCGCGCACGTGGGCAGC
TTCACGCGGGGCTTCCTGCA

Product: TPR domain-containing protein

Products: NA

Alternate protein names: O-Linked N-Acetylglucosamine Transferase; Tetratricopeptide TPR_2 Repeat Protein; TPR Domain-Containing Protein; SPINDLY Family O-Linked N-Acetylglucosamine Transferase; Tetratricopeptide TPR_1 Repeat-Containing Protein; Methyltransferase Type; TPR Repeat Protein; TPR Domain Protein; FkbM Family Methyltransferase; Glycosyl Transferase Family Protein; Tetratricopeptide Repeat-Containing Protein; SPY Protein; Glycosyltransferase TPR Domain Protein; Tetratricopeptide Repeat Domain Protein; Tpr Repeat-Containing Protein; Porphyrin Biosynthesis Protein; Transferase; Tetratricopeptide Repeat Family Protein; Sulfotransferase; TPR Domain/SEC-C Motif Domain Protein; TPR Repeat; O-Linked N-Acetylglucosamine TransferaNDLY Family; Tetratricopeptide Repeat Protein; O-Linked Acetylglucosamine Transferase; Glycosyltransferase TPR Domain-Containing Protein; Methyltransferase Regulatory Domain; Tetratricopeptide Domain Protein; TPR Repeat Domain-Containing Protein; TPR Repeat-Containing Glycosyl Transferase; O-Linked GLCNAC Transferase; Glycosyl Transferase TPR Repeat Protein

Number of amino acids: Translated: 672; Mature: 671

Protein sequence:

>672_residues
MADLDTLEMLSKLTADGCSLGDVITLASNLATGGQPALADQAYKIWIKFNPDHPQLCVALFNRSVLQAALGDSVAAAASL
EQAIQINPEFMPAYVNLGGLQERAGLQELAIATWEAGANRPIVLNGMGVSYAFTCLKQIARLLGEMHQPARAELALQRAA
DIDPKAMDVIGQLVATRLSQCKWPAVQPTERLSRETLLNGVNPLSIAAYSDDPLLQLGAANQFIEREAKTTPEQVRADRR
DAPIDLAGRRPRIGYISSDLRDHAVGYLMAELFEVHDKAKVEVFAYYCGPESSDGLNTRIRAAAEHFIDIRPMSDDEAAQ
RIVDDGIDILVDVNGHTRDARTAVFARRPAPILVNWLGYPGTMGSDYHHYIVGDPWIIPPEMELYYSEAVRRIPCYQPND
RRRIVASDVPTRTEAGLPEDGFVFCCFNGTQKITPHVFDRWMEILKRTSGSVLWLLDSNPETNARLRDAAEARGVDRMRL
VFAPKMPNAFHLARYRLADLFLDTTPYGAHTTASDALWMAVPVLTWSGRSFASRVCGSLVRSAGLPELVVDSAAAYVEKA
VEIGSDRARAQALRATLEANRDTCVLFDMDLLADKLETLYGEMIAEYQAGLRPQPNLANLATYLAVGLALDRDEREAQAE
PDLHGVYRRELARRHAVKAIAPDARLWEGQGR

Sequences:

>Translated_672_residues
MADLDTLEMLSKLTADGCSLGDVITLASNLATGGQPALADQAYKIWIKFNPDHPQLCVALFNRSVLQAALGDSVAAAASL
EQAIQINPEFMPAYVNLGGLQERAGLQELAIATWEAGANRPIVLNGMGVSYAFTCLKQIARLLGEMHQPARAELALQRAA
DIDPKAMDVIGQLVATRLSQCKWPAVQPTERLSRETLLNGVNPLSIAAYSDDPLLQLGAANQFIEREAKTTPEQVRADRR
DAPIDLAGRRPRIGYISSDLRDHAVGYLMAELFEVHDKAKVEVFAYYCGPESSDGLNTRIRAAAEHFIDIRPMSDDEAAQ
RIVDDGIDILVDVNGHTRDARTAVFARRPAPILVNWLGYPGTMGSDYHHYIVGDPWIIPPEMELYYSEAVRRIPCYQPND
RRRIVASDVPTRTEAGLPEDGFVFCCFNGTQKITPHVFDRWMEILKRTSGSVLWLLDSNPETNARLRDAAEARGVDRMRL
VFAPKMPNAFHLARYRLADLFLDTTPYGAHTTASDALWMAVPVLTWSGRSFASRVCGSLVRSAGLPELVVDSAAAYVEKA
VEIGSDRARAQALRATLEANRDTCVLFDMDLLADKLETLYGEMIAEYQAGLRPQPNLANLATYLAVGLALDRDEREAQAE
PDLHGVYRRELARRHAVKAIAPDARLWEGQGR
>Mature_671_residues
ADLDTLEMLSKLTADGCSLGDVITLASNLATGGQPALADQAYKIWIKFNPDHPQLCVALFNRSVLQAALGDSVAAAASLE
QAIQINPEFMPAYVNLGGLQERAGLQELAIATWEAGANRPIVLNGMGVSYAFTCLKQIARLLGEMHQPARAELALQRAAD
IDPKAMDVIGQLVATRLSQCKWPAVQPTERLSRETLLNGVNPLSIAAYSDDPLLQLGAANQFIEREAKTTPEQVRADRRD
APIDLAGRRPRIGYISSDLRDHAVGYLMAELFEVHDKAKVEVFAYYCGPESSDGLNTRIRAAAEHFIDIRPMSDDEAAQR
IVDDGIDILVDVNGHTRDARTAVFARRPAPILVNWLGYPGTMGSDYHHYIVGDPWIIPPEMELYYSEAVRRIPCYQPNDR
RRIVASDVPTRTEAGLPEDGFVFCCFNGTQKITPHVFDRWMEILKRTSGSVLWLLDSNPETNARLRDAAEARGVDRMRLV
FAPKMPNAFHLARYRLADLFLDTTPYGAHTTASDALWMAVPVLTWSGRSFASRVCGSLVRSAGLPELVVDSAAAYVEKAV
EIGSDRARAQALRATLEANRDTCVLFDMDLLADKLETLYGEMIAEYQAGLRPQPNLANLATYLAVGLALDRDEREAQAEP
DLHGVYRRELARRHAVKAIAPDARLWEGQGR

Specific function: Unknown

COG id: COG3914

COG function: function code O; Predicted O-linked N-acetylglucosamine transferase, SPINDLY family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307150, Length=205, Percent_Identity=36.5853658536585, Blast_Score=140, Evalue=6e-33,
Organism=Homo sapiens, GI32307148, Length=205, Percent_Identity=36.5853658536585, Blast_Score=139, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI115532692, Length=372, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI115532690, Length=372, Percent_Identity=29.0322580645161, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI17647755, Length=377, Percent_Identity=29.1777188328912, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24585827, Length=377, Percent_Identity=29.1777188328912, Blast_Score=139, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24585829, Length=377, Percent_Identity=29.1777188328912, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 74130; Mature: 73999

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLDTLEMLSKLTADGCSLGDVITLASNLATGGQPALADQAYKIWIKFNPDHPQLCVAL
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHH
FNRSVLQAALGDSVAAAASLEQAIQINPEFMPAYVNLGGLQERAGLQELAIATWEAGANR
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEHEECCCCCHHHCCHHHHHHHHCCCCCCC
PIVLNGMGVSYAFTCLKQIARLLGEMHQPARAELALQRAADIDPKAMDVIGQLVATRLSQ
CEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
CKWPAVQPTERLSRETLLNGVNPLSIAAYSDDPLLQLGAANQFIEREAKTTPEQVRADRR
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCHHHHHHHHHCCCHHHHHCCCC
DAPIDLAGRRPRIGYISSDLRDHAVGYLMAELFEVHDKAKVEVFAYYCGPESSDGLNTRI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHH
RAAAEHFIDIRPMSDDEAAQRIVDDGIDILVDVNGHTRDARTAVFARRPAPILVNWLGYP
HHHHHHHEEECCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCC
GTMGSDYHHYIVGDPWIIPPEMELYYSEAVRRIPCYQPNDRRRIVASDVPTRTEAGLPED
CCCCCCCCEEEECCCEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCC
GFVFCCFNGTQKITPHVFDRWMEILKRTSGSVLWLLDSNPETNARLRDAAEARGVDRMRL
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEE
VFAPKMPNAFHLARYRLADLFLDTTPYGAHTTASDALWMAVPVLTWSGRSFASRVCGSLV
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEEEECCHHHHHHHHHHHH
RSAGLPELVVDSAAAYVEKAVEIGSDRARAQALRATLEANRDTCVLFDMDLLADKLETLY
HHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHH
GEMIAEYQAGLRPQPNLANLATYLAVGLALDRDEREAQAEPDLHGVYRRELARRHAVKAI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHC
APDARLWEGQGR
CCCCCCCCCCCC
>Mature Secondary Structure 
ADLDTLEMLSKLTADGCSLGDVITLASNLATGGQPALADQAYKIWIKFNPDHPQLCVAL
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCHHHHHHH
FNRSVLQAALGDSVAAAASLEQAIQINPEFMPAYVNLGGLQERAGLQELAIATWEAGANR
HHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEEHEECCCCCHHHCCHHHHHHHHCCCCCCC
PIVLNGMGVSYAFTCLKQIARLLGEMHQPARAELALQRAADIDPKAMDVIGQLVATRLSQ
CEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
CKWPAVQPTERLSRETLLNGVNPLSIAAYSDDPLLQLGAANQFIEREAKTTPEQVRADRR
CCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCHHHHHHHHHCCCHHHHHCCCC
DAPIDLAGRRPRIGYISSDLRDHAVGYLMAELFEVHDKAKVEVFAYYCGPESSDGLNTRI
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHH
RAAAEHFIDIRPMSDDEAAQRIVDDGIDILVDVNGHTRDARTAVFARRPAPILVNWLGYP
HHHHHHHEEECCCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCC
GTMGSDYHHYIVGDPWIIPPEMELYYSEAVRRIPCYQPNDRRRIVASDVPTRTEAGLPED
CCCCCCCCEEEECCCEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCC
GFVFCCFNGTQKITPHVFDRWMEILKRTSGSVLWLLDSNPETNARLRDAAEARGVDRMRL
CEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCEEEE
VFAPKMPNAFHLARYRLADLFLDTTPYGAHTTASDALWMAVPVLTWSGRSFASRVCGSLV
EECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEEEEECCHHHHHHHHHHHH
RSAGLPELVVDSAAAYVEKAVEIGSDRARAQALRATLEANRDTCVLFDMDLLADKLETLY
HHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHH
GEMIAEYQAGLRPQPNLANLATYLAVGLALDRDEREAQAEPDLHGVYRRELARRHAVKAI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHC
APDARLWEGQGR
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA