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The map label for this gene is fliR

Identifier: 16125328

GI number: 16125328

Start: 1207808

End: 1208563

Strand: Direct

Name: fliR

Synonym: CC_1076

Alternate gene names: 16125328

Gene position: 1207808-1208563 (Clockwise)

Preceding gene: 16125327

Following gene: 16125329

Centisome position: 30.07

GC content: 64.95

Gene sequence:

>756_bases
TTGAACGCCTTCGCCACGGCCTTTCAGGTCTATGTCGCCGCCCTCGTCTTCGCGCGGGTGGGCGCCATGGTCATGACCAT
GCCGGGCATCGGCGACCAGGCGATTCCCGCCCGCATTCGCCTGTCGTTCGCCCTGCTGATGGCGCTCATCCTGGCGCCGC
TGGTCCAGAACACGGTCGGTCCTATCCCGAGCACCCTGGGCGGACTGGGCGGGGCGGTGATCCACGAGGTCCTGATCGGC
CTGATGATCGGTTCGGTGCTGCGCCTGTTCATGACCTCGCTGACGACGGCCGGCGAAATCATTTCGATGCAGACCACGCT
GTCGTTCGCCCAGAGCACCAATCCGTCGATGGAAGGGTCGAGCACGGCGGTGGCGACCTTCTTGTCGATGCTGGGCCTGA
CTCTGGTGATGGCCACGGACCTGCATCACCTGTTCATCGCCGCCATCGTCAAGTCGTACACGATTTTCCCGTTCACCCGC
GCCGTACCCGTCAACGACGCCGCCGCCCTGGCGGTGCAGACGGTCGCGCAGTCTTTCAGCCTGGGCGTTCAGTTGGCCGC
GCCGGTGATCGTGTTCTCTCTGGTCTTCAACCTCGCCACGGGTCTGGTCGGGCGCATCATGCCCGCGTTCCAGATCTTCT
TCGTGGCCTCGCCGCTCAGCGTGATCCTGGGCCTGTCTCTGCTGGCGCTGTCGCTGAGCGGCATCGCCATGGTCTGGACC
GACCGCTACCGCGAACTCCTGGACATCTTCACCTAG

Upstream 100 bases:

>100_bases
TCTCGCTGCTGATCTTCCTACCGCTGATGGGCTCGCTGATGAGCGGCTTCATGCGCCAGATCGCCGCCCGCATCGCCGGC
ATGTAGGAGGCGAGGGGCCC

Downstream 100 bases:

>100_bases
GGGGCGAGCATGGCGGACGATACGGATCCAGAATCGAAAACAGAAGAACCGTCAGCCAAGAAGCTGTCGGACGCCCGCGC
CAAGGGCGACGTCATCAAGT

Product: flagellar biosynthesis protein FliR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNAFATAFQVYVAALVFARVGAMVMTMPGIGDQAIPARIRLSFALLMALILAPLVQNTVGPIPSTLGGLGGAVIHEVLIG
LMIGSVLRLFMTSLTTAGEIISMQTTLSFAQSTNPSMEGSSTAVATFLSMLGLTLVMATDLHHLFIAAIVKSYTIFPFTR
AVPVNDAAALAVQTVAQSFSLGVQLAAPVIVFSLVFNLATGLVGRIMPAFQIFFVASPLSVILGLSLLALSLSGIAMVWT
DRYRELLDIFT

Sequences:

>Translated_251_residues
MNAFATAFQVYVAALVFARVGAMVMTMPGIGDQAIPARIRLSFALLMALILAPLVQNTVGPIPSTLGGLGGAVIHEVLIG
LMIGSVLRLFMTSLTTAGEIISMQTTLSFAQSTNPSMEGSSTAVATFLSMLGLTLVMATDLHHLFIAAIVKSYTIFPFTR
AVPVNDAAALAVQTVAQSFSLGVQLAAPVIVFSLVFNLATGLVGRIMPAFQIFFVASPLSVILGLSLLALSLSGIAMVWT
DRYRELLDIFT
>Mature_251_residues
MNAFATAFQVYVAALVFARVGAMVMTMPGIGDQAIPARIRLSFALLMALILAPLVQNTVGPIPSTLGGLGGAVIHEVLIG
LMIGSVLRLFMTSLTTAGEIISMQTTLSFAQSTNPSMEGSSTAVATFLSMLGLTLVMATDLHHLFIAAIVKSYTIFPFTR
AVPVNDAAALAVQTVAQSFSLGVQLAAPVIVFSLVFNLATGLVGRIMPAFQIFFVASPLSVILGLSLLALSLSGIAMVWT
DRYRELLDIFT

Specific function: Role in flagellar biosynthesis

COG id: COG1684

COG function: function code NU; Flagellar biosynthesis pathway, component FliR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential). Bacterial flagellum basal body

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family

Homologues:

Organism=Escherichia coli, GI1788261, Length=233, Percent_Identity=31.7596566523605, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLIR_CAUCR (Q45975)

Other databases:

- EMBL:   U13663
- EMBL:   AE005673
- PIR:   I40671
- RefSeq:   NP_419892.1
- GeneID:   940501
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_1076
- NMPDR:   fig|190650.1.peg.1072
- TIGR:   CC_1076
- HOGENOM:   HBG700695
- OMA:   FATDSHH
- ProtClustDB:   PRK05701
- InterPro:   IPR006303
- InterPro:   IPR002010
- PRINTS:   PR00953
- TIGRFAMs:   TIGR01400

Pfam domain/function: PF01311 Bac_export_1

EC number: NA

Molecular weight: Translated: 26413; Mature: 26413

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xddbe6b4)-; HASH(0xd8e9c04)-; HASH(0xd5b4a3c)-; HASH(0xccd01d8)-; HASH(0xc420364)-; HASH(0xe2c0864)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCH
>Mature Secondary Structure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HHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7814323; 11259647