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The map label for this gene is divJ

Identifier: 16125315

GI number: 16125315

Start: 1194522

End: 1196315

Strand: Direct

Name: divJ

Synonym: CC_1063

Alternate gene names: 16125315

Gene position: 1194522-1196315 (Clockwise)

Preceding gene: 16125311

Following gene: 16125317

Centisome position: 29.74

GC content: 72.07

Gene sequence:

>1794_bases
GTGATCCTCCCCACCGCGCTAAAAAGTCGACTGGCCTTGGAATTCGAAACGCTTCCAGACCCGTTCAGACGTCCGGCCGC
ACGCGCCGCCGGGCTCGATCCCGCGCACGCCTGGCGGCTCGGGTGGCTGGCGGCTGTCTGTCTGGCGGCGGCGGCGGCCC
TGTTCACCGCCGACTCCGGCGGTTGGCCTGTGTGGGCGGCGCTCGGCGCCGGCGCCCTGCCCGCCTTGGTCTCGCTGATC
TTCACGCGGGAGGACGAACGCACCCAGTCCTGGCTTTTGGTGCTGTGGGCCGTGGGCGGCTCGCTGGCGGCGGTGCTGAC
CGGCGGCGTGGGCGGGGCCATGGCCGCCTGGTGTCTCGCGCCCGTGGCGGCCGCCTCCACTCAGGATCAGCCCAAGCGTC
TGGCTGAGGGCGCGGCCCTGGCCCTGATCGGCGCCTGTGTCGCGGCGCTGACCCAGCTTTCCGGCCTGGCGCCCGCGGCG
CCGACGGGACCGCTGGCCTTCGTTCTGGGCTTTCTGGCGCTGGTGACGACCGGTCTTGGTCTCGCCGCCGGCCTCCTGAT
CGGCCGGCGTCGCCAGGGCGCGCGCGACGATCGCTACGCCAGCGAGATCATCGGTCTGGAGACCTTGCTCGACGGCCTGC
CGCACCTGGCGATCGCCGTCCGGGGGCAGGGACAGGTGACCGCCGTGCGCGGCGCGGCGCCGCCCGGCGTCACCCGCGCT
GATCTCGTCAATCGCGGTCTGACCGGCGCGGCTGCGCCCGGCGACCGTCAGCGCCTGACCGCCGCTATCGCCCAAGCTCA
TCGTGAGGGCTCGGCCAGCCTGACCTTCAACCCCGCGCTGGGCGTCGAGCGCGTGGTGGCCCTGGACATGCACCGCGTTG
CGCCGAACCAGCTGGTCGGCGTGCTGCGCGACATCACGGTGGAGCGGCATCGCGAGCATGCGCTCGACCAGGCGCGCATC
GACGCCGAGGCCTTGGCCGCCGGCCGCGCGCGGTTCCTAGCCAATATGAGCCATGAGCTTCGCACGCCCCTGAACGCCAT
CATGGGCTTCTCCGACATCATGCGGGCGCGGATGTTTGGTCCGCTGAGCGACCGCTACGCCGAGTACGCTGAGCTGATCC
ACGAGAGCGGCGGCCATCTGCTGGACCTGATCAACGACGTGCTGGACATGTCCAAGATCGAGGCCGAGCGGTTCGAGCTG
CAGCGCGGCGTGTTCGACGCGCGCGAGGCGGTTCAGGCGGCGATGCGGCTGCTGCGCGTTCAGTCTGACACCGCCGGAGT
TCAGCTGCGCGGCGTCCTGCCGCCCGGCGAGCTGGAGGTCGACGCCGATCGCCGCGCGCTGAAGCAGATCGTCCTGAACC
TCGTCTCGAACGCCCTGAAGTTCACCCCGCGCGGCGGGCAGGTGACCGTCACGGCGCACGGCTATGACGGCGTGCTCGAG
ATCGTGGTCGCCGATACGGGCGTCGGGATCAGTCCTGAGGACCTGGAACGCCTGGGGCGTCCCTACGAGCAGGCCGGCGG
GGCCGAACAGCGCGCGCGGGGCACGGGCCTTGGCCTGTCGCTGGTGCGGGCTTTCGCCCAGCTGCATGGCGGCGAGATGG
TGATCGAGAGCCGCCTGGGCGCAGGCACGACCGTGTCGGTGCGCCTGCCTGTGCTGCTGGCGCCGATGGTCGCTGCCACG
CCGACGCCGCCAGCCGCGCCAGAAGCGCCGTCGGCGCCGGAACCCGCTCCCACGGTTGAGGAACCGCCGCCGGCCAGCCT
GGGCGACAACGTCATCGCCTTTGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
ACGATTCCGTTTCCGTCCACAGGGCTTCCACCACGAAAGGTCGCCCGCAGATTGTGCGGGGTTGGAGGGAAGGCCCGCCC
CGCGTTAAGGTTTGACGACG

Downstream 100 bases:

>100_bases
GGCGCTCTGGTCTTACCGCAGGAACGCCCGACCGGCGGCGAAGTCTCCGACCTCGATATAGGCCTTGCGCGTGACCTCCT
CGCCGCGTCCGGCGAAGGCG

Product: sensor histidine kinase DivJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MILPTALKSRLALEFETLPDPFRRPAARAAGLDPAHAWRLGWLAAVCLAAAAALFTADSGGWPVWAALGAGALPALVSLI
FTREDERTQSWLLVLWAVGGSLAAVLTGGVGGAMAAWCLAPVAAASTQDQPKRLAEGAALALIGACVAALTQLSGLAPAA
PTGPLAFVLGFLALVTTGLGLAAGLLIGRRRQGARDDRYASEIIGLETLLDGLPHLAIAVRGQGQVTAVRGAAPPGVTRA
DLVNRGLTGAAAPGDRQRLTAAIAQAHREGSASLTFNPALGVERVVALDMHRVAPNQLVGVLRDITVERHREHALDQARI
DAEALAAGRARFLANMSHELRTPLNAIMGFSDIMRARMFGPLSDRYAEYAELIHESGGHLLDLINDVLDMSKIEAERFEL
QRGVFDAREAVQAAMRLLRVQSDTAGVQLRGVLPPGELEVDADRRALKQIVLNLVSNALKFTPRGGQVTVTAHGYDGVLE
IVVADTGVGISPEDLERLGRPYEQAGGAEQRARGTGLGLSLVRAFAQLHGGEMVIESRLGAGTTVSVRLPVLLAPMVAAT
PTPPAAPEAPSAPEPAPTVEEPPPASLGDNVIAFAPR

Sequences:

>Translated_597_residues
MILPTALKSRLALEFETLPDPFRRPAARAAGLDPAHAWRLGWLAAVCLAAAAALFTADSGGWPVWAALGAGALPALVSLI
FTREDERTQSWLLVLWAVGGSLAAVLTGGVGGAMAAWCLAPVAAASTQDQPKRLAEGAALALIGACVAALTQLSGLAPAA
PTGPLAFVLGFLALVTTGLGLAAGLLIGRRRQGARDDRYASEIIGLETLLDGLPHLAIAVRGQGQVTAVRGAAPPGVTRA
DLVNRGLTGAAAPGDRQRLTAAIAQAHREGSASLTFNPALGVERVVALDMHRVAPNQLVGVLRDITVERHREHALDQARI
DAEALAAGRARFLANMSHELRTPLNAIMGFSDIMRARMFGPLSDRYAEYAELIHESGGHLLDLINDVLDMSKIEAERFEL
QRGVFDAREAVQAAMRLLRVQSDTAGVQLRGVLPPGELEVDADRRALKQIVLNLVSNALKFTPRGGQVTVTAHGYDGVLE
IVVADTGVGISPEDLERLGRPYEQAGGAEQRARGTGLGLSLVRAFAQLHGGEMVIESRLGAGTTVSVRLPVLLAPMVAAT
PTPPAAPEAPSAPEPAPTVEEPPPASLGDNVIAFAPR
>Mature_597_residues
MILPTALKSRLALEFETLPDPFRRPAARAAGLDPAHAWRLGWLAAVCLAAAAALFTADSGGWPVWAALGAGALPALVSLI
FTREDERTQSWLLVLWAVGGSLAAVLTGGVGGAMAAWCLAPVAAASTQDQPKRLAEGAALALIGACVAALTQLSGLAPAA
PTGPLAFVLGFLALVTTGLGLAAGLLIGRRRQGARDDRYASEIIGLETLLDGLPHLAIAVRGQGQVTAVRGAAPPGVTRA
DLVNRGLTGAAAPGDRQRLTAAIAQAHREGSASLTFNPALGVERVVALDMHRVAPNQLVGVLRDITVERHREHALDQARI
DAEALAAGRARFLANMSHELRTPLNAIMGFSDIMRARMFGPLSDRYAEYAELIHESGGHLLDLINDVLDMSKIEAERFEL
QRGVFDAREAVQAAMRLLRVQSDTAGVQLRGVLPPGELEVDADRRALKQIVLNLVSNALKFTPRGGQVTVTAHGYDGVLE
IVVADTGVGISPEDLERLGRPYEQAGGAEQRARGTGLGLSLVRAFAQLHGGEMVIESRLGAGTTVSVRLPVLLAPMVAAT
PTPPAAPEAPSAPEPAPTVEEPPPASLGDNVIAFAPR

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

Organism=Escherichia coli, GI1788713, Length=434, Percent_Identity=28.3410138248848, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI145693157, Length=301, Percent_Identity=32.890365448505, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=34.1269841269841, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI48994928, Length=267, Percent_Identity=34.0823970037453, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI87081816, Length=292, Percent_Identity=31.8493150684932, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=268, Percent_Identity=30.9701492537313, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=27.1604938271605, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=27.8761061946903, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=28.3950617283951, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788549, Length=376, Percent_Identity=25.531914893617, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=30.1724137931034, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=25.4310344827586, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=27.3858921161826, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788279, Length=209, Percent_Identity=25.8373205741627, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=27.1186440677966, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789808, Length=233, Percent_Identity=27.4678111587983, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789403, Length=218, Percent_Identity=25.6880733944954, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DIVJ_CAUCR (Q03228)

Other databases:

- EMBL:   M98873
- EMBL:   AE005673
- PIR:   C87381
- RefSeq:   NP_419879.1
- ProteinModelPortal:   Q03228
- SMR:   Q03228
- DIP:   DIP-46002N
- IntAct:   Q03228
- GeneID:   940521
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_1063
- NMPDR:   fig|190650.1.peg.1059
- TIGR:   CC_1063
- HOGENOM:   HBG334875
- OMA:   VTANAHR
- ProtClustDB:   CLSK890208
- BRENDA:   2.7.13.3
- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- Gene3D:   G3DSA:3.30.565.10
- PRINTS:   PR00344
- SMART:   SM00387
- SMART:   SM00388

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; SSF55874 ATP_bd_ATPase; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 62374; Mature: 62374

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xd6475ac)-; HASH(0xe31b1fc)-; HASH(0xd9c01d4)-; HASH(0xe260870)-; HASH(0xe30eec8)-; HASH(0xdec7714)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPTALKSRLALEFETLPDPFRRPAARAAGLDPAHAWRLGWLAAVCLAAAAALFTADSG
CCCCHHHHHHHHEEECCCCCHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GWPVWAALGAGALPALVSLIFTREDERTQSWLLVLWAVGGSLAAVLTGGVGGAMAAWCLA
CCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
PVAAASTQDQPKRLAEGAALALIGACVAALTQLSGLAPAAPTGPLAFVLGFLALVTTGLG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LAAGLLIGRRRQGARDDRYASEIIGLETLLDGLPHLAIAVRGQGQVTAVRGAAPPGVTRA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCHH
DLVNRGLTGAAAPGDRQRLTAAIAQAHREGSASLTFNPALGVERVVALDMHRVAPNQLVG
HHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHH
VLRDITVERHREHALDQARIDAEALAAGRARFLANMSHELRTPLNAIMGFSDIMRARMFG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
PLSDRYAEYAELIHESGGHLLDLINDVLDMSKIEAERFELQRGVFDAREAVQAAMRLLRV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSDTAGVQLRGVLPPGELEVDADRRALKQIVLNLVSNALKFTPRGGQVTVTAHGYDGVLE
CCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCEEE
IVVADTGVGISPEDLERLGRPYEQAGGAEQRARGTGLGLSLVRAFAQLHGGEMVIESRLG
EEEECCCCCCCHHHHHHHCCCHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHCC
AGTTVSVRLPVLLAPMVAATPTPPAAPEAPSAPEPAPTVEEPPPASLGDNVIAFAPR
CCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCH
>Mature Secondary Structure
MILPTALKSRLALEFETLPDPFRRPAARAAGLDPAHAWRLGWLAAVCLAAAAALFTADSG
CCCCHHHHHHHHEEECCCCCHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GWPVWAALGAGALPALVSLIFTREDERTQSWLLVLWAVGGSLAAVLTGGVGGAMAAWCLA
CCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHH
PVAAASTQDQPKRLAEGAALALIGACVAALTQLSGLAPAAPTGPLAFVLGFLALVTTGLG
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
LAAGLLIGRRRQGARDDRYASEIIGLETLLDGLPHLAIAVRGQGQVTAVRGAAPPGVTRA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCHH
DLVNRGLTGAAAPGDRQRLTAAIAQAHREGSASLTFNPALGVERVVALDMHRVAPNQLVG
HHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCHHHHHH
VLRDITVERHREHALDQARIDAEALAAGRARFLANMSHELRTPLNAIMGFSDIMRARMFG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCC
PLSDRYAEYAELIHESGGHLLDLINDVLDMSKIEAERFELQRGVFDAREAVQAAMRLLRV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSDTAGVQLRGVLPPGELEVDADRRALKQIVLNLVSNALKFTPRGGQVTVTAHGYDGVLE
CCCCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCEEE
IVVADTGVGISPEDLERLGRPYEQAGGAEQRARGTGLGLSLVRAFAQLHGGEMVIESRLG
EEEECCCCCCCHHHHHHHCCCHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEHHCC
AGTTVSVRLPVLLAPMVAATPTPPAAPEAPSAPEPAPTVEEPPPASLGDNVIAFAPR
CCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647