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The map label for this gene is ppa

Identifier: 16124303

GI number: 16124303

Start: 49104

End: 49637

Strand: Direct

Name: ppa

Synonym: CC_0047

Alternate gene names: 16124303

Gene position: 49104-49637 (Clockwise)

Preceding gene: 16124286

Following gene: 16124304

Centisome position: 1.22

GC content: 63.48

Gene sequence:

>534_bases
ATGGACCTGTCCAAGATCGCCGTCGGCGTAAACCCGCCGTACGACCTGAACGCCATCATCGAGATCCCGCAGGGCGGCGA
GCCGGTGAAGTACGAGATCGACAAGGAAAGCGGCGCCCTGATGGTCGACCGTTTCCTGCACACGGCGATGTTCTATCCGG
CCAACTACGGTTTCATCCCGCACACCCTGGCCGACGACGGCGACCCCGCCGACATCATGGTGGTGGGTCCGACCCCGGTG
GTGCCCGGCGCGATCATCCGCTGCCGCCCGATCGGCACCCTGATGATGGTCGACGAAGCCGGCTCGGACGAGAAGATCCT
GGCCGTGCCGGTCGACAAGCTGCACCCGTTCTATACGGGCGTGACCAGCTGGCGCGACCTGCCCACCATCCTGACCGAGC
AGATCGCCCACTTCTTCCAGCACTACAAGGACCTGGAAAAGGGCAAGTCGACGAAGATCAGCGGCTGGGCCGATCCCGAC
GAGACCGCCGAGATCATCCGCACGGCGATCAAGCGTTATAACGAAAGCTACTGA

Upstream 100 bases:

>100_bases
GGGAAATCTCCGGAGTCGTCTTCCGCGCCGCAGCATTTTGGGCCTATAAGCCCAGCCGCGCAGGCCGCTCCCCAAGGGCC
GCATCTGATAAAGAGTCAAA

Downstream 100 bases:

>100_bases
GTTCGATCAGCTCTGGTGGCCGGCCCAGAGGCCGGTCACCAGCAGCGCGATGACGACCGCGTCGATCAATATGGCGATGC
GTGCGAAGCCCTTCAGGTAG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MDLSKIAVGVNPPYDLNAIIEIPQGGEPVKYEIDKESGALMVDRFLHTAMFYPANYGFIPHTLADDGDPADIMVVGPTPV
VPGAIIRCRPIGTLMMVDEAGSDEKILAVPVDKLHPFYTGVTSWRDLPTILTEQIAHFFQHYKDLEKGKSTKISGWADPD
ETAEIIRTAIKRYNESY

Sequences:

>Translated_177_residues
MDLSKIAVGVNPPYDLNAIIEIPQGGEPVKYEIDKESGALMVDRFLHTAMFYPANYGFIPHTLADDGDPADIMVVGPTPV
VPGAIIRCRPIGTLMMVDEAGSDEKILAVPVDKLHPFYTGVTSWRDLPTILTEQIAHFFQHYKDLEKGKSTKISGWADPD
ETAEIIRTAIKRYNESY
>Mature_177_residues
MDLSKIAVGVNPPYDLNAIIEIPQGGEPVKYEIDKESGALMVDRFLHTAMFYPANYGFIPHTLADDGDPADIMVVGPTPV
VPGAIIRCRPIGTLMMVDEAGSDEKILAVPVDKLHPFYTGVTSWRDLPTILTEQIAHFFQHYKDLEKGKSTKISGWADPD
ETAEIIRTAIKRYNESY

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=53.4883720930233, Blast_Score=197, Evalue=3e-52,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_CAUCR (Q9AC20)

Other databases:

- EMBL:   AE005673
- PIR:   G87254
- RefSeq:   NP_418867.1
- ProteinModelPortal:   Q9AC20
- SMR:   Q9AC20
- GeneID:   944103
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_0047
- NMPDR:   fig|190650.1.peg.47
- TIGR:   CC_0047
- HOGENOM:   HBG529150
- OMA:   PVALMKM
- ProtClustDB:   PRK01250
- BRENDA:   3.6.1.1
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 19635; Mature: 19635

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSKIAVGVNPPYDLNAIIEIPQGGEPVKYEIDKESGALMVDRFLHTAMFYPANYGFIP
CCCHHEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCC
HTLADDGDPADIMVVGPTPVVPGAIIRCRPIGTLMMVDEAGSDEKILAVPVDKLHPFYTG
CCCCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCEEEEECHHHCCHHHHC
VTSWRDLPTILTEQIAHFFQHYKDLEKGKSTKISGWADPDETAEIIRTAIKRYNESY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLSKIAVGVNPPYDLNAIIEIPQGGEPVKYEIDKESGALMVDRFLHTAMFYPANYGFIP
CCCHHEEEECCCCCCCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCC
HTLADDGDPADIMVVGPTPVVPGAIIRCRPIGTLMMVDEAGSDEKILAVPVDKLHPFYTG
CCCCCCCCCCCEEEECCCCCCCCCEEEEECCCEEEEEECCCCCCEEEEECHHHCCHHHHC
VTSWRDLPTILTEQIAHFFQHYKDLEKGKSTKISGWADPDETAEIIRTAIKRYNESY
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647