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The map label for this gene is arsC [H]

Identifier: 160903383

GI number: 160903383

Start: 2163909

End: 2164361

Strand: Direct

Name: arsC [H]

Synonym: Pmob_1954

Alternate gene names: 160903383

Gene position: 2163909-2164361 (Clockwise)

Preceding gene: 160903382

Following gene: 160903384

Centisome position: 99.74

GC content: 33.33

Gene sequence:

>453_bases
ATGAATAAGATCAAAGTTTTGTTTTTGTGTTCGAGAAATTCTGCAAGAAGTCAGATGGCTCAGGCATTTTTGAAAAAATA
CGGAAATGATAAATTTGAGGCTTACAGTGCAGGTTTAGAAGCAAGTGAAATTCATCCTTTGACCATAAAAGTCATGGAAG
AAAAAGGAATATCTATGTCCGAGCAATACTCAAAAAGTTTGGATATATACTTGAACGATAGATTTGGTTTTTTAATAACC
GTCTGTTCAAAAGCAGAAAAAGAATGTCCTTTTTTTCCGGGCGTTAGTATAAGATTATATTGGCCCTTTGACGATCCAGC
CGCTGCCAAAGGTTCTGAAGAAGAACAATTAGAAGTATTTCGAAAGGTAAGGGATCAAATAGAAAAAAAGGTAATTGATT
TCGTGGAGAATACTGATAAATACTCTAATATAAAAGATAATTTTCGAGTGTAA

Upstream 100 bases:

>100_bases
GATAAAAGATTTGACGAATTTAAAATTCAGGAAAAGAGGGCGAATATAAAAGAACTAGATGAAATTGCTAGATTAAACCA
TCAACCAAGGGAGGAGAATT

Downstream 100 bases:

>100_bases
AAACCTTTTTGCATATACTTTATTTTTCAAAGAATTAACCTTCAGCTAAAGTTTGTTTGCTATAATAAATTCATAAAAAA
ATTAATAAAGAAAAAACCTC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MNKIKVLFLCSRNSARSQMAQAFLKKYGNDKFEAYSAGLEASEIHPLTIKVMEEKGISMSEQYSKSLDIYLNDRFGFLIT
VCSKAEKECPFFPGVSIRLYWPFDDPAAAKGSEEEQLEVFRKVRDQIEKKVIDFVENTDKYSNIKDNFRV

Sequences:

>Translated_150_residues
MNKIKVLFLCSRNSARSQMAQAFLKKYGNDKFEAYSAGLEASEIHPLTIKVMEEKGISMSEQYSKSLDIYLNDRFGFLIT
VCSKAEKECPFFPGVSIRLYWPFDDPAAAKGSEEEQLEVFRKVRDQIEKKVIDFVENTDKYSNIKDNFRV
>Mature_150_residues
MNKIKVLFLCSRNSARSQMAQAFLKKYGNDKFEAYSAGLEASEIHPLTIKVMEEKGISMSEQYSKSLDIYLNDRFGFLIT
VCSKAEKECPFFPGVSIRLYWPFDDPAAAKGSEEEQLEVFRKVRDQIEKKVIDFVENTDKYSNIKDNFRV

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17330; Mature: 17330

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIKVLFLCSRNSARSQMAQAFLKKYGNDKFEAYSAGLEASEIHPLTIKVMEEKGISMS
CCCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCHH
EQYSKSLDIYLNDRFGFLITVCSKAEKECPFFPGVSIRLYWPFDDPAAAKGSEEEQLEVF
HHHCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
RKVRDQIEKKVIDFVENTDKYSNIKDNFRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKIKVLFLCSRNSARSQMAQAFLKKYGNDKFEAYSAGLEASEIHPLTIKVMEEKGISMS
CCCEEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCEEEEEECCCCCCHH
EQYSKSLDIYLNDRFGFLITVCSKAEKECPFFPGVSIRLYWPFDDPAAAKGSEEEQLEVF
HHHCCCEEEEECCCCCEEHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHH
RKVRDQIEKKVIDFVENTDKYSNIKDNFRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]