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The map label for this gene is prpE [H]

Identifier: 160903340

GI number: 160903340

Start: 2115275

End: 2115946

Strand: Direct

Name: prpE [H]

Synonym: Pmob_1911

Alternate gene names: 160903340

Gene position: 2115275-2115946 (Clockwise)

Preceding gene: 160903339

Following gene: 160903341

Centisome position: 97.5

GC content: 34.52

Gene sequence:

>672_bases
GTGATCTGGGCGATTTCAGATATCCACGGTATGTACGATACTTTAATTTCGCTTTTAAAACGGATACAGATCAAAGATTC
TGACACAATGATTTTTCTTGGTGATTATGTGGACAGAGGACCTGATTCAAAAAAGGTGCTGGATCTTTTGATTACTTTAA
GCAAACAGAGGAATCGTATTTTTTTAAAGGGGAACCATGACGATATGATGGTCGACTATTGTCAAAAAACTCATGAGTAT
GGAGAAGGTGTCTGGTTTTACAACGGTGCATTGTCGACAATTAAAAGTTTCAATAACAATATTGGGGAAGAGTACATAAA
CTTTTTAAAAGATCTACCTCTGTATTATGAGTTGGAAGTAGAAAACGAGAAATATTTGTTTGTACATGCGGGAGTTAATC
CAAAAAAGTCACTTTCAAAACAAGATAAATGGGATTTGTTGTGGATAAGAGATGAATTTTTAAGTATGTCAGAAAGGTAT
TTTAATTATACCGTTATTCATGGACATACTCCAACATTGTACTTAACAGGTGAAGATAAGATCTTTGTGAAACGTGATAA
TAATAAGAAAATAATAAGTGTAGATATAGATACGGGATGTGTGTACGGTGGGAAATTGACGGCCTTTGGAATCACTGAGG
ATAACAGACACGTAGTTTTACAAGCTGTTTGA

Upstream 100 bases:

>100_bases
GTAAAGAATTAAAAGATATGGTGAAGTAAATTCCAAAAAATGGGCAGGATTCCTGCCCATTTTTTTATGATAAAGACTTG
ATCACATGGGAGGGTTTCAA

Downstream 100 bases:

>100_bases
AAAATCGATTTAAACTTCTTTAATCGTCTTTAATTGCTTTTAAACTCTTCTAATTAAAAATACTTCGACTTTCTAACTTT
TTCAAAGAGTGATATAATTA

Product: metallophosphoesterase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MIWAISDIHGMYDTLISLLKRIQIKDSDTMIFLGDYVDRGPDSKKVLDLLITLSKQRNRIFLKGNHDDMMVDYCQKTHEY
GEGVWFYNGALSTIKSFNNNIGEEYINFLKDLPLYYELEVENEKYLFVHAGVNPKKSLSKQDKWDLLWIRDEFLSMSERY
FNYTVIHGHTPTLYLTGEDKIFVKRDNNKKIISVDIDTGCVYGGKLTAFGITEDNRHVVLQAV

Sequences:

>Translated_223_residues
MIWAISDIHGMYDTLISLLKRIQIKDSDTMIFLGDYVDRGPDSKKVLDLLITLSKQRNRIFLKGNHDDMMVDYCQKTHEY
GEGVWFYNGALSTIKSFNNNIGEEYINFLKDLPLYYELEVENEKYLFVHAGVNPKKSLSKQDKWDLLWIRDEFLSMSERY
FNYTVIHGHTPTLYLTGEDKIFVKRDNNKKIISVDIDTGCVYGGKLTAFGITEDNRHVVLQAV
>Mature_223_residues
MIWAISDIHGMYDTLISLLKRIQIKDSDTMIFLGDYVDRGPDSKKVLDLLITLSKQRNRIFLKGNHDDMMVDYCQKTHEY
GEGVWFYNGALSTIKSFNNNIGEEYINFLKDLPLYYELEVENEKYLFVHAGVNPKKSLSKQDKWDLLWIRDEFLSMSERY
FNYTVIHGHTPTLYLTGEDKIFVKRDNNKKIISVDIDTGCVYGGKLTAFGITEDNRHVVLQAV

Specific function: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prpE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.17 [H]

Molecular weight: Translated: 25968; Mature: 25968

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWAISDIHGMYDTLISLLKRIQIKDSDTMIFLGDYVDRGPDSKKVLDLLITLSKQRNRI
CEEEEHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEE
FLKGNHDDMMVDYCQKTHEYGEGVWFYNGALSTIKSFNNNIGEEYINFLKDLPLYYELEV
EEEECCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEE
ENEKYLFVHAGVNPKKSLSKQDKWDLLWIRDEFLSMSERYFNYTVIHGHTPTLYLTGEDK
CCCEEEEEECCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHEEEEEEECCCCEEEEECCCE
IFVKRDNNKKIISVDIDTGCVYGGKLTAFGITEDNRHVVLQAV
EEEEECCCCEEEEEECCCCEEECCEEEEEEECCCCCEEEEEEC
>Mature Secondary Structure
MIWAISDIHGMYDTLISLLKRIQIKDSDTMIFLGDYVDRGPDSKKVLDLLITLSKQRNRI
CEEEEHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCEE
FLKGNHDDMMVDYCQKTHEYGEGVWFYNGALSTIKSFNNNIGEEYINFLKDLPLYYELEV
EEEECCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEE
ENEKYLFVHAGVNPKKSLSKQDKWDLLWIRDEFLSMSERYFNYTVIHGHTPTLYLTGEDK
CCCEEEEEECCCCCHHHCCCCCCEEEEEEEHHHHHHHHHHEEEEEEECCCCEEEEECCCE
IFVKRDNNKKIISVDIDTGCVYGGKLTAFGITEDNRHVVLQAV
EEEEECCCCEEEEEECCCCEEECCEEEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]