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The map label for this gene is hbpA [H]

Identifier: 160903212

GI number: 160903212

Start: 1950863

End: 1952368

Strand: Direct

Name: hbpA [H]

Synonym: Pmob_1781

Alternate gene names: 160903212

Gene position: 1950863-1952368 (Clockwise)

Preceding gene: 160903206

Following gene: 160903213

Centisome position: 89.92

GC content: 38.05

Gene sequence:

>1506_bases
ATGAAAAAGTATTTGGTGAGTTTATTTGTTGTGTTGGTTTTATTTGTTGGAGTTTGGGCACAATCTACTATAGTTGTTGG
TACCACAGACAAAATTAGAACTCTAGACCCGGCTTTGTGTTATGACTACTTTTCTAGTAATATTTTACAAAATGTTTTAG
CTGGGCCAGTAGATTACAAGGTTAATTCGACGGAAATTGTTCCAAATTTATTCGAAAGTTGGGAAGTATCTGAAGATGGA
TTAGAGTATCTTTTCCACGTTCGAAAAGGTGTAGTTTTCGAAGATGGGACCCCTATAGATGCATCCATTTTTAAATTCTC
TTTCGATAGGGTTATAAACCTTGGGGGAGATCCCGCATTCTTACTTTCTGATATAGTTAAAACAACCGAAGTGGTCGATG
ATTATATCTTCAAAGTGACTCTCGATTATCCTTTTTCTGCTTTTGTATCAGTATTAGGTTACACTGTTGGTTGGCCTGTC
AATCCAAACGTATTCTCCGCAGATAGTTTTTATGATGGGGCACCTTCCGCTTCTGGTCCATACAAAGTCACCGAATGGAT
AAGAGACGTAAGAATTACATTGCAAGCAAATGACAAATACTTCGGTGAAAAACCTAAAACGGATAGGATCATCATTTTAT
TTTACGAAAACGCGGCAACGTTGAGATTAGCTTTGGAAACGGGTGAAATAGATATTGCATTCAGACATTTAGACCCAAGG
GATATACAAGATTTAAAAAGTTCTAAAAATGTTCAAGTTATCCAGGGGGAAAGTCCACAAATCAGAATGCTAGTATTCAA
TGCACAGAAAGAACCTTTCGACGATCCATTGGTAAGACAAGCGATTTCCTTAGCTGTGGAAAGAGATGTAATCGTTGAAG
ATGTATTTTTGAATATGGCATCACCACTGTACTCACTTGTACCAATGGGAATGTGGAGTCATGAAGATGTCTTCCAAGAA
GGGGATCTTGAGGCTGCAAAACAACTGTTGTATCAAGCTGGTTACGACGAAAAAAACAAACTAGTGGTTGATCTTTGGTA
CAGCCCTACTCATTATGGAACAACAGAAGCAGATGTCGCCCAAGTTTTAATGGAGTCCTTAGAAAAAACAGGAATTATCG
ATATCAACTTAGAATATGCTGAATGGGCAACCTATGTTGATTATTTCTTAAATGGAAACATGGGGATGTTCTTATTAGGT
TGGTATCCTGATTATATTGACCCTGATGATTACCTCTGGCCATTCTTAAGTGAAAATGGGGCTAGATCGATGGGTAGTTT
TTATGTCAATCCAGTAACTGAAAGTGTAATGAGGGCGGCAAGAGTAGCGACTGACCAGGAAGTTAGATCCCAATTGTACA
AATTGGTCCAACAAGATCTAGCGTTCAACGCACCATACGTTTCGCTTTGGCAAGGTGTAGAAACGGTAGCTGCCCAAAAT
AACATCAAAGGAATTTTGTTAGAACCTTCTCAAGTTTTTAGATATTATTTGCTTTACAAGGAATAA

Upstream 100 bases:

>100_bases
TGTAAAACTAGTTTTTGGTTCAGCAAATAATTAGCATAAGTTTTTGTAGTAGGGGTTTTTCAAGTATTACATATCAGCAT
ATTTTACGAGGAGGGATTTT

Downstream 100 bases:

>100_bases
TTTTCTTAAGAATTTTTTTACGTTTGAAACTAAAACAATTGCCCCGATTTTTTAAGAATCGGGGCAATTTTAAGAAAACA
AACCTCAGAAAAGAAGGGTG

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MKKYLVSLFVVLVLFVGVWAQSTIVVGTTDKIRTLDPALCYDYFSSNILQNVLAGPVDYKVNSTEIVPNLFESWEVSEDG
LEYLFHVRKGVVFEDGTPIDASIFKFSFDRVINLGGDPAFLLSDIVKTTEVVDDYIFKVTLDYPFSAFVSVLGYTVGWPV
NPNVFSADSFYDGAPSASGPYKVTEWIRDVRITLQANDKYFGEKPKTDRIIILFYENAATLRLALETGEIDIAFRHLDPR
DIQDLKSSKNVQVIQGESPQIRMLVFNAQKEPFDDPLVRQAISLAVERDVIVEDVFLNMASPLYSLVPMGMWSHEDVFQE
GDLEAAKQLLYQAGYDEKNKLVVDLWYSPTHYGTTEADVAQVLMESLEKTGIIDINLEYAEWATYVDYFLNGNMGMFLLG
WYPDYIDPDDYLWPFLSENGARSMGSFYVNPVTESVMRAARVATDQEVRSQLYKLVQQDLAFNAPYVSLWQGVETVAAQN
NIKGILLEPSQVFRYYLLYKE

Sequences:

>Translated_501_residues
MKKYLVSLFVVLVLFVGVWAQSTIVVGTTDKIRTLDPALCYDYFSSNILQNVLAGPVDYKVNSTEIVPNLFESWEVSEDG
LEYLFHVRKGVVFEDGTPIDASIFKFSFDRVINLGGDPAFLLSDIVKTTEVVDDYIFKVTLDYPFSAFVSVLGYTVGWPV
NPNVFSADSFYDGAPSASGPYKVTEWIRDVRITLQANDKYFGEKPKTDRIIILFYENAATLRLALETGEIDIAFRHLDPR
DIQDLKSSKNVQVIQGESPQIRMLVFNAQKEPFDDPLVRQAISLAVERDVIVEDVFLNMASPLYSLVPMGMWSHEDVFQE
GDLEAAKQLLYQAGYDEKNKLVVDLWYSPTHYGTTEADVAQVLMESLEKTGIIDINLEYAEWATYVDYFLNGNMGMFLLG
WYPDYIDPDDYLWPFLSENGARSMGSFYVNPVTESVMRAARVATDQEVRSQLYKLVQQDLAFNAPYVSLWQGVETVAAQN
NIKGILLEPSQVFRYYLLYKE
>Mature_501_residues
MKKYLVSLFVVLVLFVGVWAQSTIVVGTTDKIRTLDPALCYDYFSSNILQNVLAGPVDYKVNSTEIVPNLFESWEVSEDG
LEYLFHVRKGVVFEDGTPIDASIFKFSFDRVINLGGDPAFLLSDIVKTTEVVDDYIFKVTLDYPFSAFVSVLGYTVGWPV
NPNVFSADSFYDGAPSASGPYKVTEWIRDVRITLQANDKYFGEKPKTDRIIILFYENAATLRLALETGEIDIAFRHLDPR
DIQDLKSSKNVQVIQGESPQIRMLVFNAQKEPFDDPLVRQAISLAVERDVIVEDVFLNMASPLYSLVPMGMWSHEDVFQE
GDLEAAKQLLYQAGYDEKNKLVVDLWYSPTHYGTTEADVAQVLMESLEKTGIIDINLEYAEWATYVDYFLNGNMGMFLLG
WYPDYIDPDDYLWPFLSENGARSMGSFYVNPVTESVMRAARVATDQEVRSQLYKLVQQDLAFNAPYVSLWQGVETVAAQN
NIKGILLEPSQVFRYYLLYKE

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=464, Percent_Identity=28.0172413793103, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1787762, Length=491, Percent_Identity=27.4949083503055, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1787052, Length=519, Percent_Identity=26.5895953757225, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787495, Length=502, Percent_Identity=25.0996015936255, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1787551, Length=570, Percent_Identity=24.2105263157895, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789397, Length=471, Percent_Identity=24.6284501061571, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87081878, Length=480, Percent_Identity=25.2083333333333, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789887, Length=438, Percent_Identity=23.5159817351598, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56918; Mature: 56918

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYLVSLFVVLVLFVGVWAQSTIVVGTTDKIRTLDPALCYDYFSSNILQNVLAGPVDYK
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VNSTEIVPNLFESWEVSEDGLEYLFHVRKGVVFEDGTPIDASIFKFSFDRVINLGGDPAF
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHEEHHHHEECCCCHHH
LLSDIVKTTEVVDDYIFKVTLDYPFSAFVSVLGYTVGWPVNPNVFSADSFYDGAPSASGP
HHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCC
YKVTEWIRDVRITLQANDKYFGEKPKTDRIIILFYENAATLRLALETGEIDIAFRHLDPR
HHHHHHHHHEEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCEEEEEECCCCH
DIQDLKSSKNVQVIQGESPQIRMLVFNAQKEPFDDPLVRQAISLAVERDVIVEDVFLNMA
HHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SPLYSLVPMGMWSHEDVFQEGDLEAAKQLLYQAGYDEKNKLVVDLWYSPTHYGTTEADVA
HHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHH
QVLMESLEKTGIIDINLEYAEWATYVDYFLNGNMGMFLLGWYPDYIDPDDYLWPFLSENG
HHHHHHHHHCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHCCCC
ARSMGSFYVNPVTESVMRAARVATDQEVRSQLYKLVQQDLAFNAPYVSLWQGVETVAAQN
CCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
NIKGILLEPSQVFRYYLLYKE
CCCEEEECHHHHEEEEEEECC
>Mature Secondary Structure
MKKYLVSLFVVLVLFVGVWAQSTIVVGTTDKIRTLDPALCYDYFSSNILQNVLAGPVDYK
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEE
VNSTEIVPNLFESWEVSEDGLEYLFHVRKGVVFEDGTPIDASIFKFSFDRVINLGGDPAF
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHEEHHHHEECCCCHHH
LLSDIVKTTEVVDDYIFKVTLDYPFSAFVSVLGYTVGWPVNPNVFSADSFYDGAPSASGP
HHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCC
YKVTEWIRDVRITLQANDKYFGEKPKTDRIIILFYENAATLRLALETGEIDIAFRHLDPR
HHHHHHHHHEEEEEEECCCCCCCCCCCCEEEEEEECCCEEEEEEEEECCEEEEEECCCCH
DIQDLKSSKNVQVIQGESPQIRMLVFNAQKEPFDDPLVRQAISLAVERDVIVEDVFLNMA
HHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SPLYSLVPMGMWSHEDVFQEGDLEAAKQLLYQAGYDEKNKLVVDLWYSPTHYGTTEADVA
HHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHH
QVLMESLEKTGIIDINLEYAEWATYVDYFLNGNMGMFLLGWYPDYIDPDDYLWPFLSENG
HHHHHHHHHCCEEEEEEHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHCCCC
ARSMGSFYVNPVTESVMRAARVATDQEVRSQLYKLVQQDLAFNAPYVSLWQGVETVAAQN
CCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
NIKGILLEPSQVFRYYLLYKE
CCCEEEECHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]