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The map label for this gene is yicO [C]

Identifier: 160903180

GI number: 160903180

Start: 1911241

End: 1912563

Strand: Direct

Name: yicO [C]

Synonym: Pmob_1745

Alternate gene names: 160903180

Gene position: 1911241-1912563 (Clockwise)

Preceding gene: 160903179

Following gene: 160903181

Centisome position: 88.09

GC content: 39.08

Gene sequence:

>1323_bases
ATGGCAAACACTCAGCAAAAAAGTTTTTTTGAAAGGGCTTTCAAGTTAAAAGAGAACGGTACAAACGTTAGAACTGAGGT
CTTAGCAGGTATCACAACGTTTATGACGATGGCTTATATCATCTTCGTAAACCCTTCTATACTTAGTGATGCAGGAATGC
CTTTCAACGGTGTCTTCATAGCCACTATAGCTGGTGCAATTTTAGGTACCGTCATGATGGCCTTACTTACCAATTATCCG
TTTGCATTGGCTTCAGGAATGGGTTTGAACGCTTTCTTTGCCTATTCAGTCGTAATAGGTATGGGAGTCTCTTGGCAAAC
CGCTCTAGGAATAGTATTTATAGAAGGTATAATCTTTATTGTGCTTAGTGTTACACCTGTAAGAAAGATGATCGTTAATT
CGATTCCAATGAGTCTGAAAACGGGGATAAGTTCAGGAATAGGTTTATTTATAGCTTTTATAGGTTTGCAAAACGCGGGT
ATAGTAGTAGCAGATCCTGCAACATTGGTAAGAATGGGAGACTTATTCGCTGGACCAGCTTTAATAGCACTATTAGGCCT
AATTATAACGGGAATTTTACACGCTTTAAGGGTAAAAGGGGCTCTATTGTTGGGAATTATAATCGCTACAATTTTAGGAC
TATTCAACGGGGTCACACCAACACCTGAAGGCGTTGTGGCGTTGCCAAGAATGGCTGATTGGTCTCAAGTTTTGTTCCAA
CTCGATATTAGATCTGCATTTAATATCGGCATGATAGGTGTTTTAATTTCTTTCTTATTTGTAGATCTTTTTGATACGGC
AGGTACGTTGGTAGGGGTTAGTCAACAAGCGGGTTATTTGAAAGAGGACGGATCTTTACCAAAAGCAGATAGAGCTCTTT
TAGCTGACGCTATCGCTACTACAGGTGGTGCCGTATTTGGAACCAGTACGGTTACAACATACGTTGAATCTGCTTCAGGT
GTCTCAGAAGGCGGAAGAACTGGGTTAACAGGTATAGTCGTGGCTATTTTATTCTTTCTTTCTTTGTTCTTTCAACCTAT
AATAGCTATAGTTCCAGGTGCTGCAACAGCACCAGCTTTGATAATCGTCGGCGTAATGATGTTGTCGAATATAAGAAGCA
TAAAATGGGAAGATTTTACTGAAGTTTTTCCGGCTTTCGTGGCAATGATAGTAATGCCTTTAACTTATTCTATTTCAAAC
GGAATAGCTCTAGGCTTTATAACCTATCCTTTAATCAAATTATTCACTGGCAAAGGTAAAGAAGTTCACTGGTTAGTATA
CGTTTTGTGTGCTCTTTTTATTGTCTACTTTATTTGGCTTTAA

Upstream 100 bases:

>100_bases
TTCCCAAATTAAAGATAACTTGTGATGGGTTATACGACGTTGAAAATCATATCTTTGTATCATTGGTTGTAAATTGACAT
TTAAAAAGGGGGTTAAACTT

Downstream 100 bases:

>100_bases
ATTTTTTAGGTAAGGAAGTGAAGTTTTACAATGATATCAGCGGTGGTATTAGCGGCTGGAGAGTCCCTGAGGATGAAGAC
TCCAAAACAGATTTTGCCTT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MANTQQKSFFERAFKLKENGTNVRTEVLAGITTFMTMAYIIFVNPSILSDAGMPFNGVFIATIAGAILGTVMMALLTNYP
FALASGMGLNAFFAYSVVIGMGVSWQTALGIVFIEGIIFIVLSVTPVRKMIVNSIPMSLKTGISSGIGLFIAFIGLQNAG
IVVADPATLVRMGDLFAGPALIALLGLIITGILHALRVKGALLLGIIIATILGLFNGVTPTPEGVVALPRMADWSQVLFQ
LDIRSAFNIGMIGVLISFLFVDLFDTAGTLVGVSQQAGYLKEDGSLPKADRALLADAIATTGGAVFGTSTVTTYVESASG
VSEGGRTGLTGIVVAILFFLSLFFQPIIAIVPGAATAPALIIVGVMMLSNIRSIKWEDFTEVFPAFVAMIVMPLTYSISN
GIALGFITYPLIKLFTGKGKEVHWLVYVLCALFIVYFIWL

Sequences:

>Translated_440_residues
MANTQQKSFFERAFKLKENGTNVRTEVLAGITTFMTMAYIIFVNPSILSDAGMPFNGVFIATIAGAILGTVMMALLTNYP
FALASGMGLNAFFAYSVVIGMGVSWQTALGIVFIEGIIFIVLSVTPVRKMIVNSIPMSLKTGISSGIGLFIAFIGLQNAG
IVVADPATLVRMGDLFAGPALIALLGLIITGILHALRVKGALLLGIIIATILGLFNGVTPTPEGVVALPRMADWSQVLFQ
LDIRSAFNIGMIGVLISFLFVDLFDTAGTLVGVSQQAGYLKEDGSLPKADRALLADAIATTGGAVFGTSTVTTYVESASG
VSEGGRTGLTGIVVAILFFLSLFFQPIIAIVPGAATAPALIIVGVMMLSNIRSIKWEDFTEVFPAFVAMIVMPLTYSISN
GIALGFITYPLIKLFTGKGKEVHWLVYVLCALFIVYFIWL
>Mature_439_residues
ANTQQKSFFERAFKLKENGTNVRTEVLAGITTFMTMAYIIFVNPSILSDAGMPFNGVFIATIAGAILGTVMMALLTNYPF
ALASGMGLNAFFAYSVVIGMGVSWQTALGIVFIEGIIFIVLSVTPVRKMIVNSIPMSLKTGISSGIGLFIAFIGLQNAGI
VVADPATLVRMGDLFAGPALIALLGLIITGILHALRVKGALLLGIIIATILGLFNGVTPTPEGVVALPRMADWSQVLFQL
DIRSAFNIGMIGVLISFLFVDLFDTAGTLVGVSQQAGYLKEDGSLPKADRALLADAIATTGGAVFGTSTVTTYVESASGV
SEGGRTGLTGIVVAILFFLSLFFQPIIAIVPGAATAPALIIVGVMMLSNIRSIKWEDFTEVFPAFVAMIVMPLTYSISNG
IALGFITYPLIKLFTGKGKEVHWLVYVLCALFIVYFIWL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=430, Percent_Identity=44.6511627906977, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1790150, Length=444, Percent_Identity=44.8198198198198, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1790499, Length=428, Percent_Identity=35.981308411215, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI48994909, Length=437, Percent_Identity=35.2402745995423, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46643; Mature: 46512

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTQQKSFFERAFKLKENGTNVRTEVLAGITTFMTMAYIIFVNPSILSDAGMPFNGVFI
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHH
ATIAGAILGTVMMALLTNYPFALASGMGLNAFFAYSVVIGMGVSWQTALGIVFIEGIIFI
HHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLSVTPVRKMIVNSIPMSLKTGISSGIGLFIAFIGLQNAGIVVADPATLVRMGDLFAGPA
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCHH
LIALLGLIITGILHALRVKGALLLGIIIATILGLFNGVTPTPEGVVALPRMADWSQVLFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHH
LDIRSAFNIGMIGVLISFLFVDLFDTAGTLVGVSQQAGYLKEDGSLPKADRALLADAIAT
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCCCCCCCCCHHHHHHHHHHHHH
TGGAVFGTSTVTTYVESASGVSEGGRTGLTGIVVAILFFLSLFFQPIIAIVPGAATAPAL
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IIVGVMMLSNIRSIKWEDFTEVFPAFVAMIVMPLTYSISNGIALGFITYPLIKLFTGKGK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
EVHWLVYVLCALFIVYFIWL
CHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ANTQQKSFFERAFKLKENGTNVRTEVLAGITTFMTMAYIIFVNPSILSDAGMPFNGVFI
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHH
ATIAGAILGTVMMALLTNYPFALASGMGLNAFFAYSVVIGMGVSWQTALGIVFIEGIIFI
HHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VLSVTPVRKMIVNSIPMSLKTGISSGIGLFIAFIGLQNAGIVVADPATLVRMGDLFAGPA
HHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCHH
LIALLGLIITGILHALRVKGALLLGIIIATILGLFNGVTPTPEGVVALPRMADWSQVLFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHH
LDIRSAFNIGMIGVLISFLFVDLFDTAGTLVGVSQQAGYLKEDGSLPKADRALLADAIAT
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHEECCHHCCCCCCCCCCCHHHHHHHHHHHHH
TGGAVFGTSTVTTYVESASGVSEGGRTGLTGIVVAILFFLSLFFQPIIAIVPGAATAPAL
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IIVGVMMLSNIRSIKWEDFTEVFPAFVAMIVMPLTYSISNGIALGFITYPLIKLFTGKGK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
EVHWLVYVLCALFIVYFIWL
CHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]