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The map label for this gene is wecA [H]

Identifier: 160903098

GI number: 160903098

Start: 1819700

End: 1820617

Strand: Direct

Name: wecA [H]

Synonym: Pmob_1662

Alternate gene names: 160903098

Gene position: 1819700-1820617 (Clockwise)

Preceding gene: 160903097

Following gene: 160903099

Centisome position: 83.87

GC content: 29.52

Gene sequence:

>918_bases
TTGTTAGCTATAAAATTAATAAGTTCTTTTGTTTTATCTGTTATTCTAGTTCCCATTATGATAAGAATCGCAAACAAATA
TAATATCGTTGATAAACCCGACAATAAGTTGAAAGTTCATAAGTCTCCCATTCCTTATTTGGGTGGTGTAGCTGTTTTTC
TTTCAATATTACCTTTTTATTACAATGACATAGGTTTTATAATTCCTGCTAGTATATTGACTTTTATTGGTCTTTACGAT
GATATTAAGAGTGTTTCTCCTTATATTAGATTATTTGCAGAGTTTATTGTCGTCTCAATGGCAATATATTTTGTAGGAGG
AATTATTGAACCTTTTCAGTTTTTTATTTTGGTATTAACCGGTATAGCTTTAGTTAACGGAGTAAATATGGTTGATGGGA
TGGATGGAGTCTGCGCTGGAACGGCAATAGTGAGTTTGTTATTTTTTTCCTTGATATCCAAAAATTATGAACTTTTGATC
TTTGCCTTCGCAATTTTGGGGTTTCTATTATACAATTTGCCACCAGCGAAAATATTTCTTGGTGATGCGGGTTCTTATCT
TTTAGGTTTTACTTTATTTTATTCCTTTTCTTTCCTATCTGGAAGATCTGGTAGAGGAGGTTATTTCATCTCACTAATTA
TCACAGGGTTTTATTTTACTGATCTGGTTTATGCTGTGATAAGACGTTTACTCAGCAAAAGATCTCCTTTTTTAGGGGAT
AAAGAGCATATATATGATAAAATTAGAAAAAAATATAAAATAAAACCATTGTTTGTTGCATTAGTTACATATAGTATTTC
TGTTTTTTTTGGGTTGATAGGATTAATTACTTGGGATTTTCAAATAATTGGTGTTATAATTGTATTGATGTTATTTATTT
TTCTAGGTTATCATTTTAAATTGTACAAATATGAGTAA

Upstream 100 bases:

>100_bases
ATTTCATATGGTTCAGGAACATTTTGGAGTATACTTAAATCAATCCTTTTTACTAGGAGAAAGAAATCCTAAATTTTTTA
AAAATGCGGGTGAATATAAT

Downstream 100 bases:

>100_bases
TTGAAGGATTAATTTTATTAAAAAATTTTTAAAGTTTTACGTAAAAGAGGTGCTGTGATGATAATTTTAAAAGGTAATTA
TGGTGATTATATGAAACTTC

Product: glycosyl transferase family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLAIKLISSFVLSVILVPIMIRIANKYNIVDKPDNKLKVHKSPIPYLGGVAVFLSILPFYYNDIGFIIPASILTFIGLYD
DIKSVSPYIRLFAEFIVVSMAIYFVGGIIEPFQFFILVLTGIALVNGVNMVDGMDGVCAGTAIVSLLFFSLISKNYELLI
FAFAILGFLLYNLPPAKIFLGDAGSYLLGFTLFYSFSFLSGRSGRGGYFISLIITGFYFTDLVYAVIRRLLSKRSPFLGD
KEHIYDKIRKKYKIKPLFVALVTYSISVFFGLIGLITWDFQIIGVIIVLMLFIFLGYHFKLYKYE

Sequences:

>Translated_305_residues
MLAIKLISSFVLSVILVPIMIRIANKYNIVDKPDNKLKVHKSPIPYLGGVAVFLSILPFYYNDIGFIIPASILTFIGLYD
DIKSVSPYIRLFAEFIVVSMAIYFVGGIIEPFQFFILVLTGIALVNGVNMVDGMDGVCAGTAIVSLLFFSLISKNYELLI
FAFAILGFLLYNLPPAKIFLGDAGSYLLGFTLFYSFSFLSGRSGRGGYFISLIITGFYFTDLVYAVIRRLLSKRSPFLGD
KEHIYDKIRKKYKIKPLFVALVTYSISVFFGLIGLITWDFQIIGVIIVLMLFIFLGYHFKLYKYE
>Mature_305_residues
MLAIKLISSFVLSVILVPIMIRIANKYNIVDKPDNKLKVHKSPIPYLGGVAVFLSILPFYYNDIGFIIPASILTFIGLYD
DIKSVSPYIRLFAEFIVVSMAIYFVGGIIEPFQFFILVLTGIALVNGVNMVDGMDGVCAGTAIVSLLFFSLISKNYELLI
FAFAILGFLLYNLPPAKIFLGDAGSYLLGFTLFYSFSFLSGRSGRGGYFISLIITGFYFTDLVYAVIRRLLSKRSPFLGD
KEHIYDKIRKKYKIKPLFVALVTYSISVFFGLIGLITWDFQIIGVIIVLMLFIFLGYHFKLYKYE

Specific function: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55), the lipid intermediate involved in the synthesis of various bacter

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. WecA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=274, Percent_Identity=30.6569343065693, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 34386; Mature: 34386

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAIKLISSFVLSVILVPIMIRIANKYNIVDKPDNKLKVHKSPIPYLGGVAVFLSILPFY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
YNDIGFIIPASILTFIGLYDDIKSVSPYIRLFAEFIVVSMAIYFVGGIIEPFQFFILVLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIALVNGVNMVDGMDGVCAGTAIVSLLFFSLISKNYELLIFAFAILGFLLYNLPPAKIFL
HHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHEEE
GDAGSYLLGFTLFYSFSFLSGRSGRGGYFISLIITGFYFTDLVYAVIRRLLSKRSPFLGD
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KEHIYDKIRKKYKIKPLFVALVTYSISVFFGLIGLITWDFQIIGVIIVLMLFIFLGYHFK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LYKYE
EEEEC
>Mature Secondary Structure
MLAIKLISSFVLSVILVPIMIRIANKYNIVDKPDNKLKVHKSPIPYLGGVAVFLSILPFY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
YNDIGFIIPASILTFIGLYDDIKSVSPYIRLFAEFIVVSMAIYFVGGIIEPFQFFILVLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIALVNGVNMVDGMDGVCAGTAIVSLLFFSLISKNYELLIFAFAILGFLLYNLPPAKIFL
HHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHEEE
GDAGSYLLGFTLFYSFSFLSGRSGRGGYFISLIITGFYFTDLVYAVIRRLLSKRSPFLGD
CCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KEHIYDKIRKKYKIKPLFVALVTYSISVFFGLIGLITWDFQIIGVIIVLMLFIFLGYHFK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LYKYE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]