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The map label for this gene is uvrB [H]

Identifier: 160902951

GI number: 160902951

Start: 1623174

End: 1625150

Strand: Direct

Name: uvrB [H]

Synonym: Pmob_1506

Alternate gene names: 160902951

Gene position: 1623174-1625150 (Clockwise)

Preceding gene: 160902950

Following gene: 160902958

Centisome position: 74.82

GC content: 36.06

Gene sequence:

>1977_bases
ATGTTTAAGCTTCGTTCCGAATACGAACCTCAAGGCGATCAACCAAAAGCAATAGAAGAACTCTCTTCTGGGATCAATAA
AAATTATAGGTTCCAAACTTTACTGGGCGTTACTGGATCTGGTAAAACATATACAATGGCTAATATTATTGCAAACGTGA
ATCGACCAACTTTAGTTCTCTCTCCGAATAAAATCTTAGCCGTTCAACTATACAACGAATTCAAAGAGTTCTTCCCGGAA
AATAGAGTCGAATTTTTTATAAGTTATTACGATTACTATCAACCAGAAGCCTACATCCCCTCTCGAGACATATACATAGA
AAAAAATGCAGACATAAACGATATTTTAGTTAAAATGAGGCTCTCAACGTTAAAATCAGTTTTAACAAGGAGAGACGTAA
TTGTAGTTTCAAGCGTCTCAGCTATCTATGCCTCGGGCAATCCCGATGACTTTTCAAACATAAACCTTTATCTGAGAGTG
AATGAAGAGTATTCTAGAAGAGAAATCTTAATTAAACTTGGTAAAATGCAATACACAAGGCAAGAAAAAGATTATCTCGG
TGGAACGTTCAGATGGAAGGGTGATGTTTTAGAGATATTCCCTCCTTACGAAGATTTTGGAATAAGGGTAACTTTTTTCG
ATAACGAAGTCGAAAAGATCGAAGCACTTGACGTATTCAACAGAACCATAATAGAAGAATTTGATAAAATTACTATTTAT
CCAGCGAAAGAATTTGTAACCAGTCAGGAAAAGATTTTTTCAGCTATTGAAAGAATAAATGCCGATCTGCAAACCCAAAT
AGAATATTTCAAAAGGGAAGGTAAACTTTTAGAAGCTCAACGAATAGAGCAAAGGGTAAAACAAGATTTAGAATTCCTTC
AAACATTGGGATACTGTAAAGGGATAGAAAATTATTCAAGGTATTTCGATGGTAGGAATCCTGGAGACTCTCCATGGACA
CTTTTGGATTACTTCGATGAAGATTTTGTTACTTTTATTGACGAATCTCACATAGCGGTACCACAGTTAAGGGCAATGTT
CAGAGGGGATTACGCGAGGAAGAAAAATTTAGTTGATTACGGGTTTAGATTACCATCAGCCTTAGATAACAGACCTTTAA
GATTCGAAGAATTTTTAGAAAAAACCAATCAAATTATCTTTGTATCAGCTACCCCAGGGCCATTTGAAATGGAAGTATCA
GACCAAATAGTTGAACAGATTATTAGACCTACAGGACTTGTGGACCCAAAGGTTGAAGTAAAATCTACGGAAGGTCAAGT
GGACGATTTCATATCCGAAGTAAAAGAGGTTGTAGAAAGAGGAGAAAGAGCTCTAGCGGTGGTTTTAACAAAGAAAGATG
CCGAAATCCTCTCAGATCATTTAAACCTAATGGGCATTAAATCATTGTATCTACACTCTGAACTCGATACAATTGAAAGG
TCAGAGGTAATAAAAAAAATAAGAAACGGCGAAATTGAAGTAGTTGTTGGTGTAAACTTACTTAGAGAAGGGTTAGATTT
ACCGGAAGTTTCTCTTGTTGCCATAATGGATGCAGATAGAGAAGGATTTTTAAGGTCTGAAACAACGTTGATTCAAACGA
TTGGTAGAGCTGCAAGAAACGTTCAAGGTAAGGTATTACTGTACGCCGACCGAATAACGGAGGCGATGAAAACTGCCATC
GATGAAACAAACAGAAGAAGAGAAATACAGATTCAATACAATATAGATAACAACATCACTCCAAAAAGTATCATTAAAAA
ATTACCAGAAGACATGTTTGCACCATTCAAAGATAACGAGGTAAAAGAAGAAGATTATATATTCGCTGTAGAGGAGAACC
TCTCTCCGGATGATTACTTGGCTATGCTTGAAGAAAAAATGTACGAAGCAGCCTCCGAATTAAAATACGAAGAAGCAGCA
AGATACCGAGACGAGATCAAAAGGATAAAAAGAAAATACAACATCAAACAAAATTGA

Upstream 100 bases:

>100_bases
ATATCGAAACGACAAATGATTTTAAAATCAGTGCAGGATTCACTTTTAGATTCTAATATATTAGAATTTAAAGCAGAGGT
TTGATGGAGGTGTGTTTATC

Downstream 100 bases:

>100_bases
CTATAAAAAACAAAATATGGGAAGGAGATAGATAACTTAATTATCTTTCTCCTTCCCATAGTATAATATGCGCTGCTCGG
TATTTCACATACAGCTACCT

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MFKLRSEYEPQGDQPKAIEELSSGINKNYRFQTLLGVTGSGKTYTMANIIANVNRPTLVLSPNKILAVQLYNEFKEFFPE
NRVEFFISYYDYYQPEAYIPSRDIYIEKNADINDILVKMRLSTLKSVLTRRDVIVVSSVSAIYASGNPDDFSNINLYLRV
NEEYSRREILIKLGKMQYTRQEKDYLGGTFRWKGDVLEIFPPYEDFGIRVTFFDNEVEKIEALDVFNRTIIEEFDKITIY
PAKEFVTSQEKIFSAIERINADLQTQIEYFKREGKLLEAQRIEQRVKQDLEFLQTLGYCKGIENYSRYFDGRNPGDSPWT
LLDYFDEDFVTFIDESHIAVPQLRAMFRGDYARKKNLVDYGFRLPSALDNRPLRFEEFLEKTNQIIFVSATPGPFEMEVS
DQIVEQIIRPTGLVDPKVEVKSTEGQVDDFISEVKEVVERGERALAVVLTKKDAEILSDHLNLMGIKSLYLHSELDTIER
SEVIKKIRNGEIEVVVGVNLLREGLDLPEVSLVAIMDADREGFLRSETTLIQTIGRAARNVQGKVLLYADRITEAMKTAI
DETNRRREIQIQYNIDNNITPKSIIKKLPEDMFAPFKDNEVKEEDYIFAVEENLSPDDYLAMLEEKMYEAASELKYEEAA
RYRDEIKRIKRKYNIKQN

Sequences:

>Translated_658_residues
MFKLRSEYEPQGDQPKAIEELSSGINKNYRFQTLLGVTGSGKTYTMANIIANVNRPTLVLSPNKILAVQLYNEFKEFFPE
NRVEFFISYYDYYQPEAYIPSRDIYIEKNADINDILVKMRLSTLKSVLTRRDVIVVSSVSAIYASGNPDDFSNINLYLRV
NEEYSRREILIKLGKMQYTRQEKDYLGGTFRWKGDVLEIFPPYEDFGIRVTFFDNEVEKIEALDVFNRTIIEEFDKITIY
PAKEFVTSQEKIFSAIERINADLQTQIEYFKREGKLLEAQRIEQRVKQDLEFLQTLGYCKGIENYSRYFDGRNPGDSPWT
LLDYFDEDFVTFIDESHIAVPQLRAMFRGDYARKKNLVDYGFRLPSALDNRPLRFEEFLEKTNQIIFVSATPGPFEMEVS
DQIVEQIIRPTGLVDPKVEVKSTEGQVDDFISEVKEVVERGERALAVVLTKKDAEILSDHLNLMGIKSLYLHSELDTIER
SEVIKKIRNGEIEVVVGVNLLREGLDLPEVSLVAIMDADREGFLRSETTLIQTIGRAARNVQGKVLLYADRITEAMKTAI
DETNRRREIQIQYNIDNNITPKSIIKKLPEDMFAPFKDNEVKEEDYIFAVEENLSPDDYLAMLEEKMYEAASELKYEEAA
RYRDEIKRIKRKYNIKQN
>Mature_658_residues
MFKLRSEYEPQGDQPKAIEELSSGINKNYRFQTLLGVTGSGKTYTMANIIANVNRPTLVLSPNKILAVQLYNEFKEFFPE
NRVEFFISYYDYYQPEAYIPSRDIYIEKNADINDILVKMRLSTLKSVLTRRDVIVVSSVSAIYASGNPDDFSNINLYLRV
NEEYSRREILIKLGKMQYTRQEKDYLGGTFRWKGDVLEIFPPYEDFGIRVTFFDNEVEKIEALDVFNRTIIEEFDKITIY
PAKEFVTSQEKIFSAIERINADLQTQIEYFKREGKLLEAQRIEQRVKQDLEFLQTLGYCKGIENYSRYFDGRNPGDSPWT
LLDYFDEDFVTFIDESHIAVPQLRAMFRGDYARKKNLVDYGFRLPSALDNRPLRFEEFLEKTNQIIFVSATPGPFEMEVS
DQIVEQIIRPTGLVDPKVEVKSTEGQVDDFISEVKEVVERGERALAVVLTKKDAEILSDHLNLMGIKSLYLHSELDTIER
SEVIKKIRNGEIEVVVGVNLLREGLDLPEVSLVAIMDADREGFLRSETTLIQTIGRAARNVQGKVLLYADRITEAMKTAI
DETNRRREIQIQYNIDNNITPKSIIKKLPEDMFAPFKDNEVKEEDYIFAVEENLSPDDYLAMLEEKMYEAASELKYEEAA
RYRDEIKRIKRKYNIKQN

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI1786996, Length=666, Percent_Identity=50.4504504504504, Blast_Score=647, Evalue=0.0,
Organism=Escherichia coli, GI1787357, Length=291, Percent_Identity=22.680412371134, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 76548; Mature: 76548

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLRSEYEPQGDQPKAIEELSSGINKNYRFQTLLGVTGSGKTYTMANIIANVNRPTLVL
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEEHHHHHHCCCCCEEEE
SPNKILAVQLYNEFKEFFPENRVEFFISYYDYYQPEAYIPSRDIYIEKNADINDILVKMR
CCCCEEEEHHHHHHHHHCCCCHHHEEEEHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHH
LSTLKSVLTRRDVIVVSSVSAIYASGNPDDFSNINLYLRVNEEYSRREILIKLGKMQYTR
HHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
QEKDYLGGTFRWKGDVLEIFPPYEDFGIRVTFFDNEVEKIEALDVFNRTIIEEFDKITIY
HHHHHCCCEEEECCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEE
PAKEFVTSQEKIFSAIERINADLQTQIEYFKREGKLLEAQRIEQRVKQDLEFLQTLGYCK
EHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIENYSRYFDGRNPGDSPWTLLDYFDEDFVTFIDESHIAVPQLRAMFRGDYARKKNLVDY
CHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHCCCHHHHCCHHHH
GFRLPSALDNRPLRFEEFLEKTNQIIFVSATPGPFEMEVSDQIVEQIIRPTGLVDPKVEV
CCCCCHHHCCCCCCHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHCCCCCCCCCEEE
KSTEGQVDDFISEVKEVVERGERALAVVLTKKDAEILSDHLNLMGIKSLYLHSELDTIER
ECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEVIKKIRNGEIEVVVGVNLLREGLDLPEVSLVAIMDADREGFLRSETTLIQTIGRAARN
HHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
VQGKVLLYADRITEAMKTAIDETNRRREIQIQYNIDNNITPKSIIKKLPEDMFAPFKDNE
CCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCHHHCCCCCCCC
VKEEDYIFAVEENLSPDDYLAMLEEKMYEAASELKYEEAARYRDEIKRIKRKYNIKQN
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MFKLRSEYEPQGDQPKAIEELSSGINKNYRFQTLLGVTGSGKTYTMANIIANVNRPTLVL
CCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCEEEHHHHHHCCCCCEEEE
SPNKILAVQLYNEFKEFFPENRVEFFISYYDYYQPEAYIPSRDIYIEKNADINDILVKMR
CCCCEEEEHHHHHHHHHCCCCHHHEEEEHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHH
LSTLKSVLTRRDVIVVSSVSAIYASGNPDDFSNINLYLRVNEEYSRREILIKLGKMQYTR
HHHHHHHHHHCCEEEEEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
QEKDYLGGTFRWKGDVLEIFPPYEDFGIRVTFFDNEVEKIEALDVFNRTIIEEFDKITIY
HHHHHCCCEEEECCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEE
PAKEFVTSQEKIFSAIERINADLQTQIEYFKREGKLLEAQRIEQRVKQDLEFLQTLGYCK
EHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIENYSRYFDGRNPGDSPWTLLDYFDEDFVTFIDESHIAVPQLRAMFRGDYARKKNLVDY
CHHHHHHHCCCCCCCCCCCHHHHHHCCHHHHHHCCCCCCHHHHHHHHCCCHHHHCCHHHH
GFRLPSALDNRPLRFEEFLEKTNQIIFVSATPGPFEMEVSDQIVEQIIRPTGLVDPKVEV
CCCCCHHHCCCCCCHHHHHHHCCCEEEEEECCCCCEECHHHHHHHHHHCCCCCCCCCEEE
KSTEGQVDDFISEVKEVVERGERALAVVLTKKDAEILSDHLNLMGIKSLYLHSELDTIER
ECCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SEVIKKIRNGEIEVVVGVNLLREGLDLPEVSLVAIMDADREGFLRSETTLIQTIGRAARN
HHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
VQGKVLLYADRITEAMKTAIDETNRRREIQIQYNIDNNITPKSIIKKLPEDMFAPFKDNE
CCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHCCHHHCCCCCCCC
VKEEDYIFAVEENLSPDDYLAMLEEKMYEAASELKYEEAARYRDEIKRIKRKYNIKQN
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA