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The map label for this gene is vorA [H]

Identifier: 160902921

GI number: 160902921

Start: 1590308

End: 1591063

Strand: Direct

Name: vorA [H]

Synonym: Pmob_1476

Alternate gene names: 160902921

Gene position: 1590308-1591063 (Clockwise)

Preceding gene: 160902920

Following gene: 160902922

Centisome position: 73.3

GC content: 37.7

Gene sequence:

>756_bases
ATGGCCTATGCAGAAAGGTTTAAAGCACCAACATCATTAAGTGGAAAAGAGTTTACATATTGCCCAGGATGTTCTCACGG
AATTGTTCATAGATTGATCGCTGAAGTAATAGACGAACTTGACATACAAGGGAAAACTATAATGGTTGCACCTGTTGGAT
GTTCCGTATTTGCTTACGAATTTTTTGATGTAGATGGCACTGTAGCAGCTCACGGAAGGGCACCTGCCGTAGCTACTGGT
ATTAAAAGAGCCAGCCCAGATAATGTTGTTTTTACATACCAAGGAGACGGTGATTTAGCAGCTATTGGAACCGCAGAAAT
AATACATGCAGCAAACAGAGGAGAACGTATTACAACCATTTTTATAAACAATGCTATATACGGTATGACAGGAGGGCAAA
TGGCACCAACTACCCTTTTAGGAATGAAAACTACAACTACCCCATATGGAAGAAGAGAAAATATTGAAGGGTATCCCATT
CATGTTTCAGAAGTTCTAAAAGAATTGTCAGGAGTGGCGTTTCTAGCTCGTACAAAAGTTACAACTCCACAAGACGTAAT
AAAAACAAAAAAGTATTTAAAAAAGGCTTTTTATGCTCAACTCAATAATATAGGTTTTGGTTTAGTTGAAGTTTTATCAA
CATGTCCCACTAATTGGGGATTAACACCCATAGAATCTATGAAGTGGTTGGAAGATAATATGGTAAAAGAGTTCCCTTTA
GGTGTATATGTTGATAAAGTTGGAGAAGTTCGCTAA

Upstream 100 bases:

>100_bases
AAAGCCTGTAGAATTTTATGGAAGAACAGGCGGTATAATTCCAACCCCGGGAGAAGTATTGGCAAAATTAATGGAAATAA
TTTAAAAGAAGGTGAAGTTA

Downstream 100 bases:

>100_bases
TCATCTTATATTCCCTTGTTCTTACAAATATCAAAGGGAATAAATAAATGGAGGTGTTTTTATGTCATACCATGGATTAA
TAGCCGCCGGCTTTGGTGGA

Product: thiamine pyrophosphate binding domain-containing protein

Products: succinyl-CoA; CO2; reduced ferredoxin

Alternate protein names: VOR; 2-oxoisovalerate oxidoreductase alpha chain; 2-oxoisovalerate-ferredoxin oxidoreductase subunit alpha [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAYAERFKAPTSLSGKEFTYCPGCSHGIVHRLIAEVIDELDIQGKTIMVAPVGCSVFAYEFFDVDGTVAAHGRAPAVATG
IKRASPDNVVFTYQGDGDLAAIGTAEIIHAANRGERITTIFINNAIYGMTGGQMAPTTLLGMKTTTTPYGRRENIEGYPI
HVSEVLKELSGVAFLARTKVTTPQDVIKTKKYLKKAFYAQLNNIGFGLVEVLSTCPTNWGLTPIESMKWLEDNMVKEFPL
GVYVDKVGEVR

Sequences:

>Translated_251_residues
MAYAERFKAPTSLSGKEFTYCPGCSHGIVHRLIAEVIDELDIQGKTIMVAPVGCSVFAYEFFDVDGTVAAHGRAPAVATG
IKRASPDNVVFTYQGDGDLAAIGTAEIIHAANRGERITTIFINNAIYGMTGGQMAPTTLLGMKTTTTPYGRRENIEGYPI
HVSEVLKELSGVAFLARTKVTTPQDVIKTKKYLKKAFYAQLNNIGFGLVEVLSTCPTNWGLTPIESMKWLEDNMVKEFPL
GVYVDKVGEVR
>Mature_250_residues
AYAERFKAPTSLSGKEFTYCPGCSHGIVHRLIAEVIDELDIQGKTIMVAPVGCSVFAYEFFDVDGTVAAHGRAPAVATGI
KRASPDNVVFTYQGDGDLAAIGTAEIIHAANRGERITTIFINNAIYGMTGGQMAPTTLLGMKTTTTPYGRRENIEGYPIH
VSEVLKELSGVAFLARTKVTTPQDVIKTKKYLKKAFYAQLNNIGFGLVEVLSTCPTNWGLTPIESMKWLEDNMVKEFPLG
VYVDKVGEVR

Specific function: Unknown

COG id: COG1013

COG function: function code C; Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019752
- InterPro:   IPR002869
- InterPro:   IPR011766 [H]

Pfam domain/function: PF01558 POR; PF02775 TPP_enzyme_C [H]

EC number: 1.2.7.3

Molecular weight: Translated: 27334; Mature: 27203

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYAERFKAPTSLSGKEFTYCPGCSHGIVHRLIAEVIDELDIQGKTIMVAPVGCSVFAYE
CCCHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEE
FFDVDGTVAAHGRAPAVATGIKRASPDNVVFTYQGDGDLAAIGTAEIIHAANRGERITTI
EECCCCCEEECCCCCHHHHHCCCCCCCCEEEEEECCCCEEEECHHHHHHHCCCCCEEEEE
FINNAIYGMTGGQMAPTTLLGMKTTTTPYGRRENIEGYPIHVSEVLKELSGVAFLARTKV
EECCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCEEEECCCC
TTPQDVIKTKKYLKKAFYAQLNNIGFGLVEVLSTCPTNWGLTPIESMKWLEDNMVKEFPL
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
GVYVDKVGEVR
CEEECCCCCCC
>Mature Secondary Structure 
AYAERFKAPTSLSGKEFTYCPGCSHGIVHRLIAEVIDELDIQGKTIMVAPVGCSVFAYE
CCHHHHCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEE
FFDVDGTVAAHGRAPAVATGIKRASPDNVVFTYQGDGDLAAIGTAEIIHAANRGERITTI
EECCCCCEEECCCCCHHHHHCCCCCCCCEEEEEECCCCEEEECHHHHHHHCCCCCEEEEE
FINNAIYGMTGGQMAPTTLLGMKTTTTPYGRRENIEGYPIHVSEVLKELSGVAFLARTKV
EECCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEHHHHHHHHHCCEEEECCCC
TTPQDVIKTKKYLKKAFYAQLNNIGFGLVEVLSTCPTNWGLTPIESMKWLEDNMVKEFPL
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCC
GVYVDKVGEVR
CEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-oxoglutarate; CoA; oxidized ferredoxin

Specific reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9108258 [H]