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The map label for this gene is rnz [H]

Identifier: 160902038

GI number: 160902038

Start: 614159

End: 614986

Strand: Direct

Name: rnz [H]

Synonym: Pmob_0562

Alternate gene names: 160902038

Gene position: 614159-614986 (Clockwise)

Preceding gene: 160902037

Following gene: 160902039

Centisome position: 28.31

GC content: 31.76

Gene sequence:

>828_bases
TTGGAGTTTTTAATAAGATCAAAGGCATTGTATACGACTTGGGTTTTTTACAAACCAGATAGAATACTTTTCGATGCTGG
AGAAGGGGTTAGTGCAGAGTTAGGAAACAAAATATATGGAATTGAAAAGATCATTTTAACACACTCTCACGTAGATCATA
TAGCAGGATTGTGGGGAATCGTTAATACTCGCAATAACGCTATGGGGAACAGAAATAAAAAACTAGAAATTTACTATCCA
CAGGGATCGGAAAATATTAATGAATATTTAAAATTTATAGGTAAAATGAATAAAAGATTGAGATACGAAATAGATTTTAG
GGAAATAACGTTATCTGACACGATCCCTCTTAACAACAAAAGGTTTATAAAACCATTTAAAACAAGACATACCCCTGGGG
AAACCTCTTTTGGTTACCAAATTTTAGAACAAAGAAAAAGATTAAAAGAAGAGTACAGAGAACTAAAAGAGTCAGAAATA
AAAGATTTAATAATCAATAAAAAAGAAGACATCCTAGAAAACTATACTGCTAACATATTAACCATAAGCGGGGATTCGCT
ACCTATTCCCCCCAATTTCGCAAAAGATTGTGGAACGCTACTTCATGAATGTACCTTTTTTGATGAAAAGGATAGAAAAA
TTAGAAACCATACCTCTCTAGCAGAATTAAAAAATTTAATTAACATTTCCAAGCCTAAGAGAGTTATTATATACCATGTC
TCAAGTAGGTACAACAGCAAAATTAAGTCAGCCAAAGAAGAATTGAATAAAGAATTCCCAGATATACAAATAAATATCGT
CCACCCTGAAAAAGTTTTCAAGATCTAA

Upstream 100 bases:

>100_bases
ACTCACACTTTAAAAGTCAAACTTCCTCAAGGCGTGAGAGGGGAAATAAAGGTTGAAATAAAACCAGAAAACTAACAAAT
TTCAATGGGAGTTGTGATAG

Downstream 100 bases:

>100_bases
TTTTGCTGTTTTTTTGCAAAAAAGCTTTATTCGTAATGCTTTTGAGGTGATTCCTTAATCCTCATTTGCTACGCAAATGA
CGTGAGGTGATAATTATGGG

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MEFLIRSKALYTTWVFYKPDRILFDAGEGVSAELGNKIYGIEKIILTHSHVDHIAGLWGIVNTRNNAMGNRNKKLEIYYP
QGSENINEYLKFIGKMNKRLRYEIDFREITLSDTIPLNNKRFIKPFKTRHTPGETSFGYQILEQRKRLKEEYRELKESEI
KDLIINKKEDILENYTANILTISGDSLPIPPNFAKDCGTLLHECTFFDEKDRKIRNHTSLAELKNLINISKPKRVIIYHV
SSRYNSKIKSAKEELNKEFPDIQINIVHPEKVFKI

Sequences:

>Translated_275_residues
MEFLIRSKALYTTWVFYKPDRILFDAGEGVSAELGNKIYGIEKIILTHSHVDHIAGLWGIVNTRNNAMGNRNKKLEIYYP
QGSENINEYLKFIGKMNKRLRYEIDFREITLSDTIPLNNKRFIKPFKTRHTPGETSFGYQILEQRKRLKEEYRELKESEI
KDLIINKKEDILENYTANILTISGDSLPIPPNFAKDCGTLLHECTFFDEKDRKIRNHTSLAELKNLINISKPKRVIIYHV
SSRYNSKIKSAKEELNKEFPDIQINIVHPEKVFKI
>Mature_275_residues
MEFLIRSKALYTTWVFYKPDRILFDAGEGVSAELGNKIYGIEKIILTHSHVDHIAGLWGIVNTRNNAMGNRNKKLEIYYP
QGSENINEYLKFIGKMNKRLRYEIDFREITLSDTIPLNNKRFIKPFKTRHTPGETSFGYQILEQRKRLKEEYRELKESEI
KDLIINKKEDILENYTANILTISGDSLPIPPNFAKDCGTLLHECTFFDEKDRKIRNHTSLAELKNLINISKPKRVIIYHV
SSRYNSKIKSAKEELNKEFPDIQINIVHPEKVFKI

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 32236; Mature: 32236

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLIRSKALYTTWVFYKPDRILFDAGEGVSAELGNKIYGIEKIILTHSHVDHIAGLWGI
CCCHHHCCEEEEEEEEECCCEEEEECCCCCCHHHCCHHHHHHHEEEEHHHHHHHHHHHHH
VNTRNNAMGNRNKKLEIYYPQGSENINEYLKFIGKMNKRLRYEIDFREITLSDTIPLNNK
HCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCC
RFIKPFKTRHTPGETSFGYQILEQRKRLKEEYRELKESEIKDLIINKKEDILENYTANIL
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEE
TISGDSLPIPPNFAKDCGTLLHECTFFDEKDRKIRNHTSLAELKNLINISKPKRVIIYHV
EECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
SSRYNSKIKSAKEELNKEFPDIQINIVHPEKVFKI
CCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHCC
>Mature Secondary Structure
MEFLIRSKALYTTWVFYKPDRILFDAGEGVSAELGNKIYGIEKIILTHSHVDHIAGLWGI
CCCHHHCCEEEEEEEEECCCEEEEECCCCCCHHHCCHHHHHHHEEEEHHHHHHHHHHHHH
VNTRNNAMGNRNKKLEIYYPQGSENINEYLKFIGKMNKRLRYEIDFREITLSDTIPLNNK
HCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCC
RFIKPFKTRHTPGETSFGYQILEQRKRLKEEYRELKESEIKDLIINKKEDILENYTANIL
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEE
TISGDSLPIPPNFAKDCGTLLHECTFFDEKDRKIRNHTSLAELKNLINISKPKRVIIYHV
EECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
SSRYNSKIKSAKEELNKEFPDIQINIVHPEKVFKI
CCHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA