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The map label for this gene is bglA [H]

Identifier: 160901971

GI number: 160901971

Start: 534451

End: 535791

Strand: Direct

Name: bglA [H]

Synonym: Pmob_0493

Alternate gene names: 160901971

Gene position: 534451-535791 (Clockwise)

Preceding gene: 160901970

Following gene: 160901972

Centisome position: 24.63

GC content: 36.84

Gene sequence:

>1341_bases
ATGTCTGAAAAAGTTTTTCCAAAGGATTTCATGTGGGGAGCAGCTACTGCATCTTACCAAATAGAAGGTTCTCCTTTAGC
AGATGGAGCTGGTCCTTCGATTTGGCATAGGTTTTCTCATACACCTGGAAACACATATAATGGAGATACTGGAGATCTGG
CAGACGATCATTATAACAGGTACAAAGAAGATATTGCTTTGATGAAAGAGTTAGGATTAAAAGCGTACAGGTTTTCTATA
TCTTGGTCAAGAATTTTCCCAAATGGTAAAGGTAAAATCAACGAAAAAGGTGTTGATTTTTACAATAGATTGGTTGATGA
ATTACTCAAGGCAAATATAACCCCTTTTGTTACGTTGTATCATTGGGATTTACCTGCAGCTTTACAAGATCTGGGGGGTT
GGACAAACAGAGACATCGCTTATTGGTATACCGATTACGCTGACTACATGTTTCAAAGATTGGGGGACAGAGTAAAAAAT
TGGATTACTTTAAACGAACCCTGGGTAATGGCTTTTGTTGGACATTTTATGGGTGAACATGCACCTGGAATGAAAGATCT
TTATGCCGCTTTCTCAGTTGTTAACAACCAGTTGCGAGCTCATTCAAAAACGGTTAAAGCGTTCAGAGAAGAAAACGTAA
AAGAAGGGAAAATCGGAATTACTTTATCAAATACTTCTCACGATCCAGCTACGGATTCACAAGAAGATATAGATGCTGCA
CGGTTGGCACACGAATGGACAAATTATCCATTGTTTTTGAATCCAATATACAATGGTGAATATCCAAGCGGGATAAAAGA
ACATGCTTCTGTGTTTTTACCCCATAATTACGAAAATGATTTGGAAGAAATAAAAGAAAAAATCGATTTTGTAGGCATTA
ATTATTACTCTGGAGATCTTGTCAAGCTCGATACAAAATCATTCTTAGGTGGAAAAACCGTTGAAAGAGGTCTTCCAAAA
ACTGAAATGGGATGGGAGATCTACCCTGAAGGTTTCTACAAAATACTAAAAGGGGTTCAAGAAGAGTACAATCCAAAAGA
AGTGTATGTCACTGAAAATGGGGCTGCTTTTGACGACAGCGTAGTAAACCAAGAGGTACACGATGAAAATAGAATAGATT
ACTTAAAGCAGCATCTTGAACAAGCGTTAAGAGCTATTCAAAATGGAGTTACGCTCAAAGGATACTTCGTTTGGTCTTTA
TTAGACAATTTTGAATGGGCATTGGGCTATTCAAAGAGGTTTGGAATAGTGTACGTTGATTACAAAACTCAAAAAAGGAT
CATAAAAGACAGCGGTAAATGGTATTCACAGGTTATTAAGAATAATTCTTTTAATTTCTAA

Upstream 100 bases:

>100_bases
TTAGAATGAAATATGGGTGGGCTGCGGTGCGAAGGGGAGCTAAAGTAAGTTTTTGAGTTTGTATAGACAATAAAAACAAC
AACATAGGAGGAATAAAAAC

Downstream 100 bases:

>100_bases
TCTACATTTAAAAAAAGTTTTTTAATAACAAATAAAAGGATGTGAAAAAATATGGAGAAGGACATAAAAAAGTTGATCTC
TCAGATGACACTCGAAGAAA

Product: beta-galactosidase

Products: NA

Alternate protein names: Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSEKVFPKDFMWGAATASYQIEGSPLADGAGPSIWHRFSHTPGNTYNGDTGDLADDHYNRYKEDIALMKELGLKAYRFSI
SWSRIFPNGKGKINEKGVDFYNRLVDELLKANITPFVTLYHWDLPAALQDLGGWTNRDIAYWYTDYADYMFQRLGDRVKN
WITLNEPWVMAFVGHFMGEHAPGMKDLYAAFSVVNNQLRAHSKTVKAFREENVKEGKIGITLSNTSHDPATDSQEDIDAA
RLAHEWTNYPLFLNPIYNGEYPSGIKEHASVFLPHNYENDLEEIKEKIDFVGINYYSGDLVKLDTKSFLGGKTVERGLPK
TEMGWEIYPEGFYKILKGVQEEYNPKEVYVTENGAAFDDSVVNQEVHDENRIDYLKQHLEQALRAIQNGVTLKGYFVWSL
LDNFEWALGYSKRFGIVYVDYKTQKRIIKDSGKWYSQVIKNNSFNF

Sequences:

>Translated_446_residues
MSEKVFPKDFMWGAATASYQIEGSPLADGAGPSIWHRFSHTPGNTYNGDTGDLADDHYNRYKEDIALMKELGLKAYRFSI
SWSRIFPNGKGKINEKGVDFYNRLVDELLKANITPFVTLYHWDLPAALQDLGGWTNRDIAYWYTDYADYMFQRLGDRVKN
WITLNEPWVMAFVGHFMGEHAPGMKDLYAAFSVVNNQLRAHSKTVKAFREENVKEGKIGITLSNTSHDPATDSQEDIDAA
RLAHEWTNYPLFLNPIYNGEYPSGIKEHASVFLPHNYENDLEEIKEKIDFVGINYYSGDLVKLDTKSFLGGKTVERGLPK
TEMGWEIYPEGFYKILKGVQEEYNPKEVYVTENGAAFDDSVVNQEVHDENRIDYLKQHLEQALRAIQNGVTLKGYFVWSL
LDNFEWALGYSKRFGIVYVDYKTQKRIIKDSGKWYSQVIKNNSFNF
>Mature_445_residues
SEKVFPKDFMWGAATASYQIEGSPLADGAGPSIWHRFSHTPGNTYNGDTGDLADDHYNRYKEDIALMKELGLKAYRFSIS
WSRIFPNGKGKINEKGVDFYNRLVDELLKANITPFVTLYHWDLPAALQDLGGWTNRDIAYWYTDYADYMFQRLGDRVKNW
ITLNEPWVMAFVGHFMGEHAPGMKDLYAAFSVVNNQLRAHSKTVKAFREENVKEGKIGITLSNTSHDPATDSQEDIDAAR
LAHEWTNYPLFLNPIYNGEYPSGIKEHASVFLPHNYENDLEEIKEKIDFVGINYYSGDLVKLDTKSFLGGKTVERGLPKT
EMGWEIYPEGFYKILKGVQEEYNPKEVYVTENGAAFDDSVVNQEVHDENRIDYLKQHLEQALRAIQNGVTLKGYFVWSLL
DNFEWALGYSKRFGIVYVDYKTQKRIIKDSGKWYSQVIKNNSFNF

Specific function: Can Hydrolyze Salicin And Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=467, Percent_Identity=41.3276231263383, Blast_Score=337, Evalue=2e-92,
Organism=Homo sapiens, GI13273313, Length=475, Percent_Identity=36.2105263157895, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI110681710, Length=477, Percent_Identity=36.4779874213836, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI28376633, Length=454, Percent_Identity=36.784140969163, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI24497614, Length=473, Percent_Identity=32.76955602537, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=46.9387755102041, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI2367270, Length=472, Percent_Identity=33.4745762711864, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI2367174, Length=479, Percent_Identity=32.5678496868476, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1789070, Length=479, Percent_Identity=31.7327766179541, Blast_Score=187, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17552856, Length=466, Percent_Identity=37.1244635193133, Blast_Score=271, Evalue=5e-73,
Organism=Caenorhabditis elegans, GI17539390, Length=470, Percent_Identity=35.1063829787234, Blast_Score=251, Evalue=5e-67,
Organism=Drosophila melanogaster, GI21356577, Length=481, Percent_Identity=35.5509355509356, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 51359; Mature: 51228

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVFPKDFMWGAATASYQIEGSPLADGAGPSIWHRFSHTPGNTYNGDTGDLADDHYNR
CCCCCCCHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
YKEDIALMKELGLKAYRFSISWSRIFPNGKGKINEKGVDFYNRLVDELLKANITPFVTLY
HHHHHHHHHHCCCEEEEEEEEEHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEE
HWDLPAALQDLGGWTNRDIAYWYTDYADYMFQRLGDRVKNWITLNEPWVMAFVGHFMGEH
ECCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHCC
APGMKDLYAAFSVVNNQLRAHSKTVKAFREENVKEGKIGITLSNTSHDPATDSQEDIDAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
RLAHEWTNYPLFLNPIYNGEYPSGIKEHASVFLPHNYENDLEEIKEKIDFVGINYYSGDL
HHHHHHCCCCEEEECCCCCCCCCCHHHHCEEECCCCCCHHHHHHHHHHCEEEEEEECCCE
VKLDTKSFLGGKTVERGLPKTEMGWEIYPEGFYKILKGVQEEYNPKEVYVTENGAAFDDS
EEECCHHHCCCCHHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
VVNQEVHDENRIDYLKQHLEQALRAIQNGVTLKGYFVWSLLDNFEWALGYSKRFGIVYVD
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCHHHCCCCCCCCEEEEE
YKTQKRIIKDSGKWYSQVIKNNSFNF
CHHHHHHHHCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEKVFPKDFMWGAATASYQIEGSPLADGAGPSIWHRFSHTPGNTYNGDTGDLADDHYNR
CCCCCCHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHH
YKEDIALMKELGLKAYRFSISWSRIFPNGKGKINEKGVDFYNRLVDELLKANITPFVTLY
HHHHHHHHHHCCCEEEEEEEEEHEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEE
HWDLPAALQDLGGWTNRDIAYWYTDYADYMFQRLGDRVKNWITLNEPWVMAFVGHFMGEH
ECCCHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCEECCCCHHHHHHHHHHHCC
APGMKDLYAAFSVVNNQLRAHSKTVKAFREENVKEGKIGITLSNTSHDPATDSQEDIDAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHH
RLAHEWTNYPLFLNPIYNGEYPSGIKEHASVFLPHNYENDLEEIKEKIDFVGINYYSGDL
HHHHHHCCCCEEEECCCCCCCCCCHHHHCEEECCCCCCHHHHHHHHHHCEEEEEEECCCE
VKLDTKSFLGGKTVERGLPKTEMGWEIYPEGFYKILKGVQEEYNPKEVYVTENGAAFDDS
EEECCHHHCCCCHHHHCCCCCCCCCEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHH
VVNQEVHDENRIDYLKQHLEQALRAIQNGVTLKGYFVWSLLDNFEWALGYSKRFGIVYVD
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHCCHHHCCCCCCCCEEEEE
YKTQKRIIKDSGKWYSQVIKNNSFNF
CHHHHHHHHCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8277941 [H]