Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 160877297

GI number: 160877297

Start: 4960111

End: 4960788

Strand: Reverse

Name: gph [C]

Synonym: Sbal195_4194

Alternate gene names: 160877297

Gene position: 4960788-4960111 (Counterclockwise)

Preceding gene: 160877298

Following gene: 160877296

Centisome position: 92.77

GC content: 49.26

Gene sequence:

>678_bases
ATGTGGGATAAGATTAAAGCGATAGCGTTTGATCTTGATGGCACGCTGATCGACAGTGTGCCGGACCTAGCCGTTGCCAC
GCAGGAAGCCTTAGCCGAGTTAAGTTTGAAGAGCTGCTCTGAGGCGCAAGTGCGTACTTGGGTCGGTAACGGTGCCGAAA
TGTTAATGCGCCGCGCCATGACCCATGCCTTGGGAGCGGATGTGGAGCAAACCGCGCTGGATGCGGCCATGCCGATTTTT
ATGCATCACTATCAAGAGAATCTTGAGAAGCACAGTGCGCTTTATAGCGACGTGCATCAAGTACTGCAAACCTTGTTCGA
TGCAGGTTTTAAGCTCGCCGTTGTCACCAATAAACCCTATCGTTTTACCTTGCCATTACTCAATGCCTTTGGGATTAATG
ACCTTTTCAGCTTAGTGTTAGGAGGCGACACTCTCGCTAAGATGAAGCCCGATCCTTTGCCGCTACAGCACTTATTACAT
GAGTGGCAATTGGATAAAGAGGCGTTATTGATGGTCGGCGACTCTAAAAACGACATTTTAGCGGCGAAAGCGGCTGGGAT
AGCGTCAATCGGCTTGACCTACGGCTACAACTACGGTGAAGATATTGGGCTCAGTGGCCCAGATGCCGTATGTGAGCAAT
TTAGTGAGATTTTGAACTGGGTAAAACCTCTCAAGTAA

Upstream 100 bases:

>100_bases
CTGACATGTTTGTTGCGGGTTCTGCCATTTTCGGCAAGCCAGATTACAAAACCGTTGTTGATGAGATGCGTGCCGAACTT
GCTAAAGTTGGGGCATAAGC

Downstream 100 bases:

>100_bases
TAGGTGTTTACCCGTTCTTTAGTCGATTTTTTATAGTCTTTTTAATATAGATAGTGGAGCAATGACGTAATGACCAAACC
CATAGTACTCAGCGGTGCAC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MWDKIKAIAFDLDGTLIDSVPDLAVATQEALAELSLKSCSEAQVRTWVGNGAEMLMRRAMTHALGADVEQTALDAAMPIF
MHHYQENLEKHSALYSDVHQVLQTLFDAGFKLAVVTNKPYRFTLPLLNAFGINDLFSLVLGGDTLAKMKPDPLPLQHLLH
EWQLDKEALLMVGDSKNDILAAKAAGIASIGLTYGYNYGEDIGLSGPDAVCEQFSEILNWVKPLK

Sequences:

>Translated_225_residues
MWDKIKAIAFDLDGTLIDSVPDLAVATQEALAELSLKSCSEAQVRTWVGNGAEMLMRRAMTHALGADVEQTALDAAMPIF
MHHYQENLEKHSALYSDVHQVLQTLFDAGFKLAVVTNKPYRFTLPLLNAFGINDLFSLVLGGDTLAKMKPDPLPLQHLLH
EWQLDKEALLMVGDSKNDILAAKAAGIASIGLTYGYNYGEDIGLSGPDAVCEQFSEILNWVKPLK
>Mature_225_residues
MWDKIKAIAFDLDGTLIDSVPDLAVATQEALAELSLKSCSEAQVRTWVGNGAEMLMRRAMTHALGADVEQTALDAAMPIF
MHHYQENLEKHSALYSDVHQVLQTLFDAGFKLAVVTNKPYRFTLPLLNAFGINDLFSLVLGGDTLAKMKPDPLPLQHLLH
EWQLDKEALLMVGDSKNDILAAKAAGIASIGLTYGYNYGEDIGLSGPDAVCEQFSEILNWVKPLK

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=233, Percent_Identity=42.0600858369099, Blast_Score=172, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24700; Mature: 24700

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWDKIKAIAFDLDGTLIDSVPDLAVATQEALAELSLKSCSEAQVRTWVGNGAEMLMRRAM
CCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
THALGADVEQTALDAAMPIFMHHYQENLEKHSALYSDVHQVLQTLFDAGFKLAVVTNKPY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
RFTLPLLNAFGINDLFSLVLGGDTLAKMKPDPLPLQHLLHEWQLDKEALLMVGDSKNDIL
EEEHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHCCCHHHEEEECCCCCCEE
AAKAAGIASIGLTYGYNYGEDIGLSGPDAVCEQFSEILNWVKPLK
HHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWDKIKAIAFDLDGTLIDSVPDLAVATQEALAELSLKSCSEAQVRTWVGNGAEMLMRRAM
CCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHH
THALGADVEQTALDAAMPIFMHHYQENLEKHSALYSDVHQVLQTLFDAGFKLAVVTNKPY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCE
RFTLPLLNAFGINDLFSLVLGGDTLAKMKPDPLPLQHLLHEWQLDKEALLMVGDSKNDIL
EEEHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHCCCHHHEEEECCCCCCEE
AAKAAGIASIGLTYGYNYGEDIGLSGPDAVCEQFSEILNWVKPLK
HHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA