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The map label for this gene is gntR [H]

Identifier: 160877279

GI number: 160877279

Start: 4941407

End: 4942405

Strand: Reverse

Name: gntR [H]

Synonym: Sbal195_4176

Alternate gene names: 160877279

Gene position: 4942405-4941407 (Counterclockwise)

Preceding gene: 160877280

Following gene: 160877277

Centisome position: 92.43

GC content: 47.55

Gene sequence:

>999_bases
ATGAATAAAAAGCGTAGACCCACTCTTCAAGACGTTGCCGATCAAGTTGGGATCACCAAAATGACGGTGAGCCGCTATTT
AAAAAATCCAACAAGGGTGGCGCAAAGCACTCAAGAAAAGATAGCTATCGCGCTAGAAACCTTAGGTTATATACCTAATC
GCGCGCCGGAAATTTTGGCGCAAGCAACCAGCCGCGCCATTGGCGTGTTAGTGCCGTCGTTAACCAACCAAGTGTTTGCC
GAAGTGCTGCGCGGTATCGAGAATGTGACTGGAAAACGCGGTTATCAAACCATGCTGGCTCACTACGGATATCAGGCAGA
ATTAGAAGAGGAGCGGGTGGCATCACTGCTTTCTTACAATATTGATGGCTTACTTTTATCCGAAAGTTACCACACGCCGC
GTACCGTGCGAATGATTGAAACGGCGGGCATTCCGGTCATTGAAATGATGGATAGTGTGTCGCCTTCAATTCAACAGTGT
GTGGGGTTCGATAACACAGCTGCCGCATACGAAATGGTTAAGGCCATGATTGCACAAGGCTATCGCCACATTGCTTACTT
AGGCGCGCGCATGGATATTCGCACTCAGCTTAAGATGCGAGGCTACGAGTTAGCGATGCAGGAAGCCAAGCTCACACCTT
TGGCAATGACCACCAATGAGGCCTCATCGTTTTCCTTGGGGGCGTCGTTATTGCAACAAACCTTAGCGAAATATCCCTAT
GTGGATAGCTTTTTCTGCACTAACGATGATTTGGCTGCGGGGGTGATATTTGAGTGTCAAAGACAAGGCATTAAGATCCC
AGAACAAATAGGCGTTGCAGGGTTTCATGGCCATGATATTGGGCAATCCATGACGCCAAAATTGGCGAGCATTATTACCC
CGAGAAAGGAGATTGGCCGAATTGCTGCCACTGAGTTATTAGACCGATTAAATGGCAAAGAGATAGCAGAATCGGTTATC
GATCTGGGTTATCGCATTGATTTAGGGGAAACATTGTAG

Upstream 100 bases:

>100_bases
AAAATCTCGTCTGATGCTTATGTCTACTATTTGTTTATATTCGATATTTTAGCTATACATCTCACCCATACCCGCGGCTT
GTTAACTAACATTAGATACT

Downstream 100 bases:

>100_bases
ACTTCCCCTTGATCTTTCGCTTAACGGCTAATGCCTAATGTTTTTGATCACTGGCTAGCGTTAGAGAAACGCTGAGATGA
TGACTGCAACTATGCCGCCC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNKKRRPTLQDVADQVGITKMTVSRYLKNPTRVAQSTQEKIAIALETLGYIPNRAPEILAQATSRAIGVLVPSLTNQVFA
EVLRGIENVTGKRGYQTMLAHYGYQAELEEERVASLLSYNIDGLLLSESYHTPRTVRMIETAGIPVIEMMDSVSPSIQQC
VGFDNTAAAYEMVKAMIAQGYRHIAYLGARMDIRTQLKMRGYELAMQEAKLTPLAMTTNEASSFSLGASLLQQTLAKYPY
VDSFFCTNDDLAAGVIFECQRQGIKIPEQIGVAGFHGHDIGQSMTPKLASIITPRKEIGRIAATELLDRLNGKEIAESVI
DLGYRIDLGETL

Sequences:

>Translated_332_residues
MNKKRRPTLQDVADQVGITKMTVSRYLKNPTRVAQSTQEKIAIALETLGYIPNRAPEILAQATSRAIGVLVPSLTNQVFA
EVLRGIENVTGKRGYQTMLAHYGYQAELEEERVASLLSYNIDGLLLSESYHTPRTVRMIETAGIPVIEMMDSVSPSIQQC
VGFDNTAAAYEMVKAMIAQGYRHIAYLGARMDIRTQLKMRGYELAMQEAKLTPLAMTTNEASSFSLGASLLQQTLAKYPY
VDSFFCTNDDLAAGVIFECQRQGIKIPEQIGVAGFHGHDIGQSMTPKLASIITPRKEIGRIAATELLDRLNGKEIAESVI
DLGYRIDLGETL
>Mature_332_residues
MNKKRRPTLQDVADQVGITKMTVSRYLKNPTRVAQSTQEKIAIALETLGYIPNRAPEILAQATSRAIGVLVPSLTNQVFA
EVLRGIENVTGKRGYQTMLAHYGYQAELEEERVASLLSYNIDGLLLSESYHTPRTVRMIETAGIPVIEMMDSVSPSIQQC
VGFDNTAAAYEMVKAMIAQGYRHIAYLGARMDIRTQLKMRGYELAMQEAKLTPLAMTTNEASSFSLGASLLQQTLAKYPY
VDSFFCTNDDLAAGVIFECQRQGIKIPEQIGVAGFHGHDIGQSMTPKLASIITPRKEIGRIAATELLDRLNGKEIAESVI
DLGYRIDLGETL

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=330, Percent_Identity=60, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=47.7341389728097, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=29.3929712460064, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1790194, Length=307, Percent_Identity=26.3843648208469, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788474, Length=303, Percent_Identity=25.0825082508251, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=25.7328990228013, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=24.2902208201893, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789202, Length=290, Percent_Identity=23.7931034482759, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787906, Length=340, Percent_Identity=25.5882352941176, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=26.0061919504644, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786540, Length=314, Percent_Identity=23.8853503184713, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790689, Length=323, Percent_Identity=23.5294117647059, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786268, Length=286, Percent_Identity=23.4265734265734, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36612; Mature: 36612

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKRRPTLQDVADQVGITKMTVSRYLKNPTRVAQSTQEKIAIALETLGYIPNRAPEILA
CCCCCCCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QATSRAIGVLVPSLTNQVFAEVLRGIENVTGKRGYQTMLAHYGYQAELEEERVASLLSYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCC
IDGLLLSESYHTPRTVRMIETAGIPVIEMMDSVSPSIQQCVGFDNTAAAYEMVKAMIAQG
CCCEEEECCCCCCHHEEEHHHCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHH
YRHIAYLGARMDIRTQLKMRGYELAMQEAKLTPLAMTTNEASSFSLGASLLQQTLAKYPY
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
VDSFFCTNDDLAAGVIFECQRQGIKIPEQIGVAGFHGHDIGQSMTPKLASIITPRKEIGR
CCCEEECCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHH
IAATELLDRLNGKEIAESVIDLGYRIDLGETL
HHHHHHHHHCCHHHHHHHHHHCCCEECCCCCC
>Mature Secondary Structure
MNKKRRPTLQDVADQVGITKMTVSRYLKNPTRVAQSTQEKIAIALETLGYIPNRAPEILA
CCCCCCCCHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QATSRAIGVLVPSLTNQVFAEVLRGIENVTGKRGYQTMLAHYGYQAELEEERVASLLSYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCC
IDGLLLSESYHTPRTVRMIETAGIPVIEMMDSVSPSIQQCVGFDNTAAAYEMVKAMIAQG
CCCEEEECCCCCCHHEEEHHHCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHH
YRHIAYLGARMDIRTQLKMRGYELAMQEAKLTPLAMTTNEASSFSLGASLLQQTLAKYPY
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
VDSFFCTNDDLAAGVIFECQRQGIKIPEQIGVAGFHGHDIGQSMTPKLASIITPRKEIGR
CCCEEECCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHH
IAATELLDRLNGKEIAESVIDLGYRIDLGETL
HHHHHHHHHCCHHHHHHHHHHCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]