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The map label for this gene is pdhR [H]

Identifier: 160877159

GI number: 160877159

Start: 4787722

End: 4788474

Strand: Reverse

Name: pdhR [H]

Synonym: Sbal195_4055

Alternate gene names: 160877159

Gene position: 4788474-4787722 (Counterclockwise)

Preceding gene: 160877160

Following gene: 160877158

Centisome position: 89.55

GC content: 49.67

Gene sequence:

>753_bases
ATGGCCTATAGTAAAATTAATCAGCCAAAAATTTCTGATGTGATCATGGCTCAATTAGAGCAGATGATCTTAGAGGGCAG
TTTGCAGCCCGGTCAGAAGTTACCGCCTGAACGCGAACTGGCGATCCAGTTTGAAGTGTCTCGACCTTCTTTGCGTGAAG
CTATCCAAAAGCTTGAGGCAAAAGGACTGTTAATGCGCCGCCAAGGCGGTGGTACTTATGTCAAAGAGCAACTCTGGCAG
AGCCTTGCCGATCCTATCGTTGAACTTATGAATTCTGATCCAGAGAGTCAATACGACTTGCTGGAGTTCCGTCATGCTAC
CGAAGGCATGATGGCTTATTTTGCGGCGCTGCGTGGTACTGACGCCGATATGCAAAATATCAAACGTATGATCCTCGAGG
TGGAAGCCGCCACCGATATCGAAAAACAAGCCGCCGCCATTGTGCGCTTTTATCGTGCCGTTGCCGAAGCGTCACATAAC
GTGGCTATGTTACACCTCGTTCTCAGTTTAACCCCTGTGCTGCATCAAAATGTGGCGCAAAACTTGGAGCTTTTAAGCCG
CCGCGAAGAAGCTTCTACTATGGCTAACGATCACAGACGGGCCTTGCTCGCTGCCATCGTTCGTCGTGATCCCGAAGCCG
CCAGAGAAGCCTCGAATGAACACTTAAGTTACATCGAAGAGGTGATGTTATCTGTGCGGGAAGAAGATAGCCGGTTGCAG
CGAAGCTTGCGCCGTTTAAAGAGTGGCGCTTAA

Upstream 100 bases:

>100_bases
AAGGAGTGATCTTCAATCTGGACATCAAAACGCTGATTTGATAAAGTGCGCTCACTCAAAAAAATTGGTAAGACCAATTT
ACAACGGAGCTGAGCGCCTG

Downstream 100 bases:

>100_bases
GTTCTGTAGTTTAGCTGCCTGCTAAATCGGAATATGCCGCAAACACCATTCATTATCATGTATATAGAGAAGGACAGTGT
CATGTCTGAAGATATGCTAC

Product: transcriptional regulator PdhR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MAYSKINQPKISDVIMAQLEQMILEGSLQPGQKLPPERELAIQFEVSRPSLREAIQKLEAKGLLMRRQGGGTYVKEQLWQ
SLADPIVELMNSDPESQYDLLEFRHATEGMMAYFAALRGTDADMQNIKRMILEVEAATDIEKQAAAIVRFYRAVAEASHN
VAMLHLVLSLTPVLHQNVAQNLELLSRREEASTMANDHRRALLAAIVRRDPEAAREASNEHLSYIEEVMLSVREEDSRLQ
RSLRRLKSGA

Sequences:

>Translated_250_residues
MAYSKINQPKISDVIMAQLEQMILEGSLQPGQKLPPERELAIQFEVSRPSLREAIQKLEAKGLLMRRQGGGTYVKEQLWQ
SLADPIVELMNSDPESQYDLLEFRHATEGMMAYFAALRGTDADMQNIKRMILEVEAATDIEKQAAAIVRFYRAVAEASHN
VAMLHLVLSLTPVLHQNVAQNLELLSRREEASTMANDHRRALLAAIVRRDPEAAREASNEHLSYIEEVMLSVREEDSRLQ
RSLRRLKSGA
>Mature_249_residues
AYSKINQPKISDVIMAQLEQMILEGSLQPGQKLPPERELAIQFEVSRPSLREAIQKLEAKGLLMRRQGGGTYVKEQLWQS
LADPIVELMNSDPESQYDLLEFRHATEGMMAYFAALRGTDADMQNIKRMILEVEAATDIEKQAAAIVRFYRAVAEASHNV
AMLHLVLSLTPVLHQNVAQNLELLSRREEASTMANDHRRALLAAIVRRDPEAAREASNEHLSYIEEVMLSVREEDSRLQR
SLRRLKSGA

Specific function: Transcriptional repressor for the pyruvate dehydrogenase complex genes aceEF and lpd [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786303, Length=233, Percent_Identity=58.3690987124464, Blast_Score=276, Evalue=8e-76,
Organism=Escherichia coli, GI1790032, Length=239, Percent_Identity=34.7280334728033, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789353, Length=238, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790780, Length=230, Percent_Identity=30, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082208, Length=226, Percent_Identity=29.646017699115, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI48994955, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789621, Length=233, Percent_Identity=27.8969957081545, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28291; Mature: 28160

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSKINQPKISDVIMAQLEQMILEGSLQPGQKLPPERELAIQFEVSRPSLREAIQKLEA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
KGLLMRRQGGGTYVKEQLWQSLADPIVELMNSDPESQYDLLEFRHATEGMMAYFAALRGT
HHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DADMQNIKRMILEVEAATDIEKQAAAIVRFYRAVAEASHNVAMLHLVLSLTPVLHQNVAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
NLELLSRREEASTMANDHRRALLAAIVRRDPEAAREASNEHLSYIEEVMLSVREEDSRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RSLRRLKSGA
HHHHHHHCCC
>Mature Secondary Structure 
AYSKINQPKISDVIMAQLEQMILEGSLQPGQKLPPERELAIQFEVSRPSLREAIQKLEA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHH
KGLLMRRQGGGTYVKEQLWQSLADPIVELMNSDPESQYDLLEFRHATEGMMAYFAALRGT
HHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
DADMQNIKRMILEVEAATDIEKQAAAIVRFYRAVAEASHNVAMLHLVLSLTPVLHQNVAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
NLELLSRREEASTMANDHRRALLAAIVRRDPEAAREASNEHLSYIEEVMLSVREEDSRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
RSLRRLKSGA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]