Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 160876802

GI number: 160876802

Start: 4362699

End: 4364036

Strand: Direct

Name: csd [H]

Synonym: Sbal195_3698

Alternate gene names: 160876802

Gene position: 4362699-4364036 (Clockwise)

Preceding gene: 160876799

Following gene: 160876803

Centisome position: 81.59

GC content: 49.78

Gene sequence:

>1338_bases
ATGACTGAACCTGCATCGCCTACGCCAAATGCTGTGACTCACACAGCGACGAATACTGTTACCTCACATCCTTCGGCAAG
TGCCTCTCCTGATGTCACTGTGGTTCTTTGTTCATTAGAGGCAGAGCAGCGCAATGCTAAAATTAGGTCGCAATTCCCAG
CGTTAAATCAACTGCTTGATGGCTATCCCTTGTGTTATCTCGACACCGCAGCCACCAGCCAGAAGCCACAAATGGTGTTA
GATACCATGGCGCAGTTTTACGCTAACGACAATGCCAATGTGCACCGCGCGGCGCACCAGTTATCGGCGCGCTCGACCTT
AAGTTATGAAAAAGTGCGCGATCAACTACAGCAATTTTTAAAGGCCGAACGCCGCGAAGAAATCATCTTTACCCACGGCA
CCACAGAATCAATCAACTTAGTCGCCTTTGGACTCACTGCACACGTAAGCGCAGGTGATGTGATATTAATCGACGCCGCC
GCCCACCACGCCAATATCGTACCTTGGCAGGAGCTGGCAAAACGCACGGGCGCTGTGATTAAGCCAATCCCTATCGATCA
AGCTTGCCGCTTAGATGTCAGCGCCTATAAAACCTTGCTCGAGTTAAAGCCAAAAATCGTCGCGCTTTGCCATGTTTCCA
ACGCCCTAGGCACAGTCAATCCCGTGGCTCAGTTAGTTCAGTTAGCAAAAGCCCAAGGTGCAATAACCTTAGTTGATGGT
GCGCAAGCAGTGGCGCATTTAACGCTGGATGTGGCTGAAATCGATTGTGATTTTTACGTTTTTTCGGGGCATAAAATGTA
TGGCCCCACTGGCGTTGGCGTGCTTTATGGCCGTTTCGACGTGTTAGATAATCTTGCGCCACTATTAACTGGCGGCGAGA
TGATTAAACGCGTGAGTTTTGAGGCGACTGAATTTGGCAGCCTACCGAATCGCTTAGAAGCGGGCACGCCGCCGATTGCC
GAAGTCATAGGTTTAGGCGCGGCCATTACATTTTTACAAACCGAGCTTACACCGCAGGTTCAAGCTTATGAAGCTGAATT
AGTTAACTATTTACAAAGCCAATTGCGCGCGCTCGGTGAAGTGCATTTATACGGCGCTTTTGATGACAATATCGGCGTCG
TCGCCTTTAATCTTGCCGATGAACATCATCAAGATGTGGGCATTTTACTGGATCAACAAGGAATTGCCGTGCGCTGCGGC
CATCACTGCGCCATGCCATTAATGCAGAGCCTGAATCTTAAGGGCTGTTGCCGCGCCTCTATCGGTATCTACACCAATAA
AGACGACATCGACCGCTTTATTGCTGCGTTGGCCTCGGTAAAAGACTTGCTGCTGTGA

Upstream 100 bases:

>100_bases
GCCTTCCAATGTCAACGCCTCAGCAAACCGCTAAAACTTGCATTAACATGGCAGATCACAGAAGATCCCTTGGCCTTTTT
CATTGCCTTTAGCCTCATCT

Downstream 100 bases:

>100_bases
TCCAGTATTTAACGACTGAACCACGCGACTCATGTGCTCAAGATCAGTTACGCTCAAGACAAGTTATGCTCAAATAAGTG
AGACAGGATTTAGCCCTATG

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTEPASPTPNAVTHTATNTVTSHPSASASPDVTVVLCSLEAEQRNAKIRSQFPALNQLLDGYPLCYLDTAATSQKPQMVL
DTMAQFYANDNANVHRAAHQLSARSTLSYEKVRDQLQQFLKAERREEIIFTHGTTESINLVAFGLTAHVSAGDVILIDAA
AHHANIVPWQELAKRTGAVIKPIPIDQACRLDVSAYKTLLELKPKIVALCHVSNALGTVNPVAQLVQLAKAQGAITLVDG
AQAVAHLTLDVAEIDCDFYVFSGHKMYGPTGVGVLYGRFDVLDNLAPLLTGGEMIKRVSFEATEFGSLPNRLEAGTPPIA
EVIGLGAAITFLQTELTPQVQAYEAELVNYLQSQLRALGEVHLYGAFDDNIGVVAFNLADEHHQDVGILLDQQGIAVRCG
HHCAMPLMQSLNLKGCCRASIGIYTNKDDIDRFIAALASVKDLLL

Sequences:

>Translated_445_residues
MTEPASPTPNAVTHTATNTVTSHPSASASPDVTVVLCSLEAEQRNAKIRSQFPALNQLLDGYPLCYLDTAATSQKPQMVL
DTMAQFYANDNANVHRAAHQLSARSTLSYEKVRDQLQQFLKAERREEIIFTHGTTESINLVAFGLTAHVSAGDVILIDAA
AHHANIVPWQELAKRTGAVIKPIPIDQACRLDVSAYKTLLELKPKIVALCHVSNALGTVNPVAQLVQLAKAQGAITLVDG
AQAVAHLTLDVAEIDCDFYVFSGHKMYGPTGVGVLYGRFDVLDNLAPLLTGGEMIKRVSFEATEFGSLPNRLEAGTPPIA
EVIGLGAAITFLQTELTPQVQAYEAELVNYLQSQLRALGEVHLYGAFDDNIGVVAFNLADEHHQDVGILLDQQGIAVRCG
HHCAMPLMQSLNLKGCCRASIGIYTNKDDIDRFIAALASVKDLLL
>Mature_444_residues
TEPASPTPNAVTHTATNTVTSHPSASASPDVTVVLCSLEAEQRNAKIRSQFPALNQLLDGYPLCYLDTAATSQKPQMVLD
TMAQFYANDNANVHRAAHQLSARSTLSYEKVRDQLQQFLKAERREEIIFTHGTTESINLVAFGLTAHVSAGDVILIDAAA
HHANIVPWQELAKRTGAVIKPIPIDQACRLDVSAYKTLLELKPKIVALCHVSNALGTVNPVAQLVQLAKAQGAITLVDGA
QAVAHLTLDVAEIDCDFYVFSGHKMYGPTGVGVLYGRFDVLDNLAPLLTGGEMIKRVSFEATEFGSLPNRLEAGTPPIAE
VIGLGAAITFLQTELTPQVQAYEAELVNYLQSQLRALGEVHLYGAFDDNIGVVAFNLADEHHQDVGILLDQQGIAVRCGH
HCAMPLMQSLNLKGCCRASIGIYTNKDDIDRFIAALASVKDLLL

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=379, Percent_Identity=25.8575197889182, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI156713448, Length=291, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787970, Length=400, Percent_Identity=46.75, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1789175, Length=401, Percent_Identity=38.9027431421446, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI48994898, Length=399, Percent_Identity=25.5639097744361, Blast_Score=128, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI25143064, Length=295, Percent_Identity=27.7966101694915, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193211090, Length=381, Percent_Identity=24.6719160104987, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319831, Length=387, Percent_Identity=25.5813953488372, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI20129463, Length=346, Percent_Identity=28.9017341040462, Blast_Score=128, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022471
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 48011; Mature: 47880

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00595 AA_TRANSFER_CLASS_5 ; PS00226 IF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPASPTPNAVTHTATNTVTSHPSASASPDVTVVLCSLEAEQRNAKIRSQFPALNQLLD
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHCCHHHHHCHHHHHHHC
GYPLCYLDTAATSQKPQMVLDTMAQFYANDNANVHRAAHQLSARSTLSYEKVRDQLQQFL
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAERREEIIFTHGTTESINLVAFGLTAHVSAGDVILIDAAAHHANIVPWQELAKRTGAVI
HHHCCCEEEEECCCCCCEEEEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHCCCEE
KPIPIDQACRLDVSAYKTLLELKPKIVALCHVSNALGTVNPVAQLVQLAKAQGAITLVDG
ECCCCCHHHCCCHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHCCCEEEECC
AQAVAHLTLDVAEIDCDFYVFSGHKMYGPTGVGVLYGRFDVLDNLAPLLTGGEMIKRVSF
HHHHHHHEEEEEEECEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCC
EATEFGSLPNRLEAGTPPIAEVIGLGAAITFLQTELTPQVQAYEAELVNYLQSQLRALGE
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
VHLYGAFDDNIGVVAFNLADEHHQDVGILLDQQGIAVRCGHHCAMPLMQSLNLKGCCRAS
EEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCHHHHHHHHCCCCCCEEECC
IGIYTNKDDIDRFIAALASVKDLLL
CCEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEPASPTPNAVTHTATNTVTSHPSASASPDVTVVLCSLEAEQRNAKIRSQFPALNQLLD
CCCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHCCHHHHHCHHHHHHHC
GYPLCYLDTAATSQKPQMVLDTMAQFYANDNANVHRAAHQLSARSTLSYEKVRDQLQQFL
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAERREEIIFTHGTTESINLVAFGLTAHVSAGDVILIDAAAHHANIVPWQELAKRTGAVI
HHHCCCEEEEECCCCCCEEEEEEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHCCCEE
KPIPIDQACRLDVSAYKTLLELKPKIVALCHVSNALGTVNPVAQLVQLAKAQGAITLVDG
ECCCCCHHHCCCHHHHHHHHHCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHCCCEEEECC
AQAVAHLTLDVAEIDCDFYVFSGHKMYGPTGVGVLYGRFDVLDNLAPLLTGGEMIKRVSF
HHHHHHHEEEEEEECEEEEEEECCEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCC
EATEFGSLPNRLEAGTPPIAEVIGLGAAITFLQTELTPQVQAYEAELVNYLQSQLRALGE
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
VHLYGAFDDNIGVVAFNLADEHHQDVGILLDQQGIAVRCGHHCAMPLMQSLNLKGCCRAS
EEEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCEEECCCHHHHHHHHCCCCCCEEECC
IGIYTNKDDIDRFIAALASVKDLLL
CCEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]