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The map label for this gene is lysS

Identifier: 160876720

GI number: 160876720

Start: 4257048

End: 4258550

Strand: Reverse

Name: lysS

Synonym: Sbal195_3614

Alternate gene names: 160876720

Gene position: 4258550-4257048 (Counterclockwise)

Preceding gene: 160876721

Following gene: 160876719

Centisome position: 79.64

GC content: 47.57

Gene sequence:

>1503_bases
ATGACTGAACAAGTAATTGATGAGAACAAACTGATCGCCGAGCGCCGTGCCAAGCTAGAAAGCATCCGCCCAAACTGTAG
TGCTAATGCGCATCCAAATACCTTCCGTCGCACCCATAAAGCGGCTGAACTGCAAGCACAGTATGGTCAAAACACTAAAG
AAGAACTCGAAGCCTTAGGTTTTAAGACCAGCATTGCTGGCCGCATCATGGCAAAACGTGGTCCTTTCTTAGTGATCCAA
GACGTGTCTGGCCGTATTCAAGCCTATGCTGAAAAAAGCGTACAAGCTGATTTGAAAGAGCGTTTTCAAGGTCTGGATAT
CGGTGACATTATCGGTGTAACCGGTCAGCTGCATTTGTCTGGCAAAGGCGACTTATACGTCAACATGGAACAGTACGAGC
TACTGACCAAGGCGCTGCGTCCATTGCCTGCGGACTATTATGGTCTCGCCGATCAAGAAATGCGCTACCGTCAACGTTAC
GTGGATCTGATCGTTAACGAAGATTCTCGCAATGCCTTTATCATGCGTTCTAAAGTGGTTTCTGCAATCCGTAACTTCAT
GATCAAAAAAGAGTTCATGGAAGTTGAAACCCCTATGATGCACGTGATCCCAGGTGGCGCTTCGGCCCGTCCTTTTATCA
CTCATCACAACGCCTTAGACATGCCAATGTACCTGCGTATCGCGCCAGAATTATATCTGAAGCGTTTAGTGGTAGGTGGT
TTTGAGCGTGTGTTCGAAATCAACCGTAACTTCCGTAACGAAGGTCTGTCGCCACGTCATAACCCAGAATTCACTATGAT
GGAATTCTATATGGCTTATGCAGACTACAAAGATCTGATGGACTTAACCGAAGAAATGCTCAGCTCGATTGCTATCGAAC
TGCTCGGCAGTGCGCAAATGCCATACGGCGAGCACACTGTTGATTTCGGTGGCCCATACGCACGTTTAAGCATGTTAGAA
GCAATTCAGAAGTACAATCCTGATAACGCCACTATCCAAGCTATGACCTATGAGCAAGTGAAAGATGTTGAATTCATGCG
CGATCTAGCGAAAAGCTTAGGTATGAAGATTGAGAAGTTCTGGACTTGTGGTCAGCTGCTTGAAGAAATCTTCGGTGAAA
CCGCTGAATGGCAATTGATGCAACCGACGTTCATCACTGGCTACCCTGCGGACATTTCACCACTGGCACGTCGTAACGAT
GACAACCATTTCATCACTGACCGTTTCGAATTCTTCATCGGTGGCCGCGAAGTGGCTAACGGCTTTAGCGAGCTGAACGA
TGCTGAAGATCAAGACAACCGCTTTAAAGCGCAGGTTGACGCGAAAGATGCTGGCGACGATGAAGCTATGTTCTACGATG
CAGACTATATCACTGCACTAGAGCACGGTTTGCCACCAACGGCAGGTCAAGGTATTGGTATCGACCGTTTAGTGATGTTG
TTCACTAACACTCATACTATCCGTGACGTGATCCTGTTCCCAGCGATGCGCCCACAGGCGTAA

Upstream 100 bases:

>100_bases
CGCAATACTCAAGCGGTACTCGATGGCGATCTGGATAAGTTTATCGAAGCCAGTTTGAAATCTGGGCTGTAATTAATTCA
AGGTATAGACGAGAAATAAG

Downstream 100 bases:

>100_bases
TGCAGTCGAACAAGGCATTTCGTCGTTGTACATTTTGTTGCATTAGCTCTTAGCCACGCGACTTTTAGTAAGTCGTAACA
GGTTAAGTTTGCAGTGATTG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTEQVIDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQAQYGQNTKEELEALGFKTSIAGRIMAKRGPFLVIQ
DVSGRIQAYAEKSVQADLKERFQGLDIGDIIGVTGQLHLSGKGDLYVNMEQYELLTKALRPLPADYYGLADQEMRYRQRY
VDLIVNEDSRNAFIMRSKVVSAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGG
FERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAIELLGSAQMPYGEHTVDFGGPYARLSMLE
AIQKYNPDNATIQAMTYEQVKDVEFMRDLAKSLGMKIEKFWTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRND
DNHFITDRFEFFIGGREVANGFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVML
FTNTHTIRDVILFPAMRPQA

Sequences:

>Translated_500_residues
MTEQVIDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQAQYGQNTKEELEALGFKTSIAGRIMAKRGPFLVIQ
DVSGRIQAYAEKSVQADLKERFQGLDIGDIIGVTGQLHLSGKGDLYVNMEQYELLTKALRPLPADYYGLADQEMRYRQRY
VDLIVNEDSRNAFIMRSKVVSAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGG
FERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAIELLGSAQMPYGEHTVDFGGPYARLSMLE
AIQKYNPDNATIQAMTYEQVKDVEFMRDLAKSLGMKIEKFWTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRND
DNHFITDRFEFFIGGREVANGFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVML
FTNTHTIRDVILFPAMRPQA
>Mature_499_residues
TEQVIDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQAQYGQNTKEELEALGFKTSIAGRIMAKRGPFLVIQD
VSGRIQAYAEKSVQADLKERFQGLDIGDIIGVTGQLHLSGKGDLYVNMEQYELLTKALRPLPADYYGLADQEMRYRQRYV
DLIVNEDSRNAFIMRSKVVSAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGGF
ERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAIELLGSAQMPYGEHTVDFGGPYARLSMLEA
IQKYNPDNATIQAMTYEQVKDVEFMRDLAKSLGMKIEKFWTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRNDD
NHFITDRFEFFIGGREVANGFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVMLF
TNTHTIRDVILFPAMRPQA

Specific function: Unknown

COG id: COG1190

COG function: function code J; Lysyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI5031815, Length=514, Percent_Identity=41.2451361867704, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI194272210, Length=514, Percent_Identity=41.2451361867704, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI45439306, Length=350, Percent_Identity=23.7142857142857, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI40789249, Length=254, Percent_Identity=26.7716535433071, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789256, Length=502, Percent_Identity=59.9601593625498, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI1790571, Length=502, Percent_Identity=59.7609561752988, Blast_Score=617, Evalue=1e-178,
Organism=Escherichia coli, GI87082379, Length=341, Percent_Identity=31.9648093841642, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1788173, Length=254, Percent_Identity=24.4094488188976, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17535925, Length=504, Percent_Identity=40.6746031746032, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17535927, Length=504, Percent_Identity=40.6746031746032, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71994340, Length=505, Percent_Identity=40.7920792079208, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI32566633, Length=322, Percent_Identity=25.4658385093168, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551876, Length=375, Percent_Identity=25.6, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320242, Length=522, Percent_Identity=41.3793103448276, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6324256, Length=381, Percent_Identity=30.7086614173228, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6323011, Length=337, Percent_Identity=26.1127596439169, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325153, Length=348, Percent_Identity=25.5747126436782, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640849, Length=516, Percent_Identity=40.3100775193798, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24640851, Length=516, Percent_Identity=40.3100775193798, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24584738, Length=333, Percent_Identity=26.1261261261261, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYK_SHEB5 (A3D0Y5)

Other databases:

- EMBL:   CP000563
- RefSeq:   YP_001049267.1
- ProteinModelPortal:   A3D0Y5
- SMR:   A3D0Y5
- STRING:   A3D0Y5
- GeneID:   4842850
- GenomeReviews:   CP000563_GR
- KEGG:   sbl:Sbal_0873
- NMPDR:   fig|325240.3.peg.171
- eggNOG:   COG1190
- HOGENOM:   HBG631383
- OMA:   GHPQMMS
- PhylomeDB:   A3D0Y5
- ProtClustDB:   PRK00484
- GO:   GO:0005737
- HAMAP:   MF_00252
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR002313
- InterPro:   IPR018149
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF4
- PRINTS:   PR00982
- TIGRFAMs:   TIGR00499

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.6

Molecular weight: Translated: 57026; Mature: 56895

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQVIDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQAQYGQNTKEELEALG
CCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
FKTSIAGRIMAKRGPFLVIQDVSGRIQAYAEKSVQADLKERFQGLDIGDIIGVTGQLHLS
CHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEC
GKGDLYVNMEQYELLTKALRPLPADYYGLADQEMRYRQRYVDLIVNEDSRNAFIMRSKVV
CCCCEEEEHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHEECCCCCCEEHHHHHHH
SAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGG
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCCHHEEECHHHHHHHHHHHH
FERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAIELLGSAQM
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PYGEHTVDFGGPYARLSMLEAIQKYNPDNATIQAMTYEQVKDVEFMRDLAKSLGMKIEKF
CCCCCEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHH
WTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRNDDNHFITDRFEFFIGGREVAN
HHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCHHHHCCCCCCEEHHHHHHEECCHHHHH
GFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVML
HHHHCCCCCCCCCCEEEEECCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHH
FTNTHTIRDVILFPAMRPQA
HHCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEQVIDENKLIAERRAKLESIRPNCSANAHPNTFRRTHKAAELQAQYGQNTKEELEALG
CCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHC
FKTSIAGRIMAKRGPFLVIQDVSGRIQAYAEKSVQADLKERFQGLDIGDIIGVTGQLHLS
CHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEEC
GKGDLYVNMEQYELLTKALRPLPADYYGLADQEMRYRQRYVDLIVNEDSRNAFIMRSKVV
CCCCEEEEHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHEECCCCCCEEHHHHHHH
SAIRNFMIKKEFMEVETPMMHVIPGGASARPFITHHNALDMPMYLRIAPELYLKRLVVGG
HHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCCCCCCHHEEECHHHHHHHHHHHH
FERVFEINRNFRNEGLSPRHNPEFTMMEFYMAYADYKDLMDLTEEMLSSIAIELLGSAQM
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PYGEHTVDFGGPYARLSMLEAIQKYNPDNATIQAMTYEQVKDVEFMRDLAKSLGMKIEKF
CCCCCEECCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHH
WTCGQLLEEIFGETAEWQLMQPTFITGYPADISPLARRNDDNHFITDRFEFFIGGREVAN
HHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCHHHHCCCCCCEEHHHHHHEECCHHHHH
GFSELNDAEDQDNRFKAQVDAKDAGDDEAMFYDADYITALEHGLPPTAGQGIGIDRLVML
HHHHCCCCCCCCCCEEEEECCCCCCCCCEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHH
FTNTHTIRDVILFPAMRPQA
HHCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA