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The map label for this gene is alsR [H]

Identifier: 160876582

GI number: 160876582

Start: 4098361

End: 4099299

Strand: Direct

Name: alsR [H]

Synonym: Sbal195_3476

Alternate gene names: 160876582

Gene position: 4098361-4099299 (Clockwise)

Preceding gene: 160876580

Following gene: 160876584

Centisome position: 76.64

GC content: 38.23

Gene sequence:

>939_bases
ATGATTATTGAAAATGTATTTATTAATAATTATTGGTTTCTAACTATGCTCAATCCTATTTGGCTTAACACTTTTAAAAC
ATTGGTCGATGTTGGACACTTCACCAAAACGGCCGAATTGCTCCACATGACGCAACCTGGGGTAAGCCAGCACATAAATA
AACTAGAAGCTGCATGCGGTTATCCTCTAATAAAGAGATTTAACAAAAAGTTTGAGTTAACAATCTATGGGCGTAAAGTT
TACGATTATGCTGTCAAACATTTTGAAGAAGAGTCTGAACTATTACAGAATTTGGCACACGACGAACCTTTCCGAGGTCG
CTGTACTATTGGCTGTTCGGGAACTTTCGCCTGGTTGATTTATTCAGAATTACTTTCTTTGCAAACGAGTTATCCAGACT
TATCCATTGAGTTAGAAGCAACACCAAACCAACGTATATTTGAGCAAGTACTACAGGGAAAATTGGATATAGGTTTAGTG
ACAAAAGAACCCAATCCTAAATATTTTGCGAGCCGTATTATTGGTGCGGAGTGTCTTGCTCTTGTGCTGCCACTTTCCGC
AGACGAAAACTTATCTATAAATGAATTGTTAATGGAGTTGGGAGTAGTTCGTCATCCAGATTTGGCTCACTATTTCCAAA
CTTATGTTAATCAAGCCCACAATGATTTACTTAGTTTGGTCGATTTAGAGAATGTTTCGACACAAAGCTACATTAACCAA
GTGCATCAAATATTGGTTCCTATAGCTAAGGGTATCGGTTTTACGGTGGTTCCTCGATGGTGCGTCAACCTGTTCGCAGC
CAAAGAACAGCTAAAAATATTCAATATTACCGCAGAGATACAGGAGCCTGTGTACTTGGTTAGCAAACTTAATTCACCAC
TTGCTAGGCGTTATGAACAGATCATTAAAGTTATCGAGAACTCTTTTGATATTGGTTGA

Upstream 100 bases:

>100_bases
TTTTCATTAACCTATTTGACTCTCTCTGGTTGAAGTTCGTCATGAGTTTGTGGTTCTCTCTGAGCGATAGGGACACAAAG
GGTGATTTTCAGTATAATTA

Downstream 100 bases:

>100_bases
TGTAAGTTAAGAACTACTATTCAGAAGCTATTAGCTTTTTGATCTTATATCTGACCTAGGAATGAATACAAAAAGGTTGG
CATCAGAGCCAACCTTTTGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MIIENVFINNYWFLTMLNPIWLNTFKTLVDVGHFTKTAELLHMTQPGVSQHINKLEAACGYPLIKRFNKKFELTIYGRKV
YDYAVKHFEEESELLQNLAHDEPFRGRCTIGCSGTFAWLIYSELLSLQTSYPDLSIELEATPNQRIFEQVLQGKLDIGLV
TKEPNPKYFASRIIGAECLALVLPLSADENLSINELLMELGVVRHPDLAHYFQTYVNQAHNDLLSLVDLENVSTQSYINQ
VHQILVPIAKGIGFTVVPRWCVNLFAAKEQLKIFNITAEIQEPVYLVSKLNSPLARRYEQIIKVIENSFDIG

Sequences:

>Translated_312_residues
MIIENVFINNYWFLTMLNPIWLNTFKTLVDVGHFTKTAELLHMTQPGVSQHINKLEAACGYPLIKRFNKKFELTIYGRKV
YDYAVKHFEEESELLQNLAHDEPFRGRCTIGCSGTFAWLIYSELLSLQTSYPDLSIELEATPNQRIFEQVLQGKLDIGLV
TKEPNPKYFASRIIGAECLALVLPLSADENLSINELLMELGVVRHPDLAHYFQTYVNQAHNDLLSLVDLENVSTQSYINQ
VHQILVPIAKGIGFTVVPRWCVNLFAAKEQLKIFNITAEIQEPVYLVSKLNSPLARRYEQIIKVIENSFDIG
>Mature_312_residues
MIIENVFINNYWFLTMLNPIWLNTFKTLVDVGHFTKTAELLHMTQPGVSQHINKLEAACGYPLIKRFNKKFELTIYGRKV
YDYAVKHFEEESELLQNLAHDEPFRGRCTIGCSGTFAWLIYSELLSLQTSYPDLSIELEATPNQRIFEQVLQGKLDIGLV
TKEPNPKYFASRIIGAECLALVLPLSADENLSINELLMELGVVRHPDLAHYFQTYVNQAHNDLLSLVDLENVSTQSYINQ
VHQILVPIAKGIGFTVVPRWCVNLFAAKEQLKIFNITAEIQEPVYLVSKLNSPLARRYEQIIKVIENSFDIG

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=182, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787879, Length=248, Percent_Identity=23.3870967741935, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI48994962, Length=196, Percent_Identity=27.0408163265306, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35679; Mature: 35679

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIENVFINNYWFLTMLNPIWLNTFKTLVDVGHFTKTAELLHMTQPGVSQHINKLEAACG
CEECEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
YPLIKRFNKKFELTIYGRKVYDYAVKHFEEESELLQNLAHDEPFRGRCTIGCSGTFAWLI
CHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
YSELLSLQTSYPDLSIELEATPNQRIFEQVLQGKLDIGLVTKEPNPKYFASRIIGAECLA
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
LVLPLSADENLSINELLMELGVVRHPDLAHYFQTYVNQAHNDLLSLVDLENVSTQSYINQ
HHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VHQILVPIAKGIGFTVVPRWCVNLFAAKEQLKIFNITAEIQEPVYLVSKLNSPLARRYEQ
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCHHHHHHHH
IIKVIENSFDIG
HHHHHHHHCCCC
>Mature Secondary Structure
MIIENVFINNYWFLTMLNPIWLNTFKTLVDVGHFTKTAELLHMTQPGVSQHINKLEAACG
CEECEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
YPLIKRFNKKFELTIYGRKVYDYAVKHFEEESELLQNLAHDEPFRGRCTIGCSGTFAWLI
CHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHH
YSELLSLQTSYPDLSIELEATPNQRIFEQVLQGKLDIGLVTKEPNPKYFASRIIGAECLA
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
LVLPLSADENLSINELLMELGVVRHPDLAHYFQTYVNQAHNDLLSLVDLENVSTQSYINQ
HHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
VHQILVPIAKGIGFTVVPRWCVNLFAAKEQLKIFNITAEIQEPVYLVSKLNSPLARRYEQ
HHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCHHHHHHHH
IIKVIENSFDIG
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]