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The map label for this gene is deoA [H]

Identifier: 160876471

GI number: 160876471

Start: 3973675

End: 3975006

Strand: Reverse

Name: deoA [H]

Synonym: Sbal195_3365

Alternate gene names: 160876471

Gene position: 3975006-3973675 (Counterclockwise)

Preceding gene: 160876472

Following gene: 160876470

Centisome position: 74.34

GC content: 47.9

Gene sequence:

>1332_bases
ATGTTTCTAGCTCAAGAGATTATTCGTAAAAAACGTAATGGTTTAGCGCTAAGTTCCGAAGAAATACAGTTCTTTGTTCA
AGGTATCACCACCAACTCTGTATCTGAAGGTCAGATCGCCGCATTAGGTATGGCGGTGTATTTTAATGACATGAATATGG
ATGAAAGAATCGCTTTAACGACAGCAATGCGTGATTCTGGCACTGTGCTTAATTGGCAATCATTGGGACTCAACGGTCCT
GTCATCGACAAACACAGCACTGGTGGTGTCGGCGATGTGATTAGTCTCATGCTTGGCCCTATGGCTGCGGCGTGTGGCGG
TTATGTGCCTATGATTTCTGGGCGCGGCCTAGGTCATACTGGCGGTACACTCGATAAGTTTGATGCCATTCAGGGTTACC
AAACTGAGCCTTCAAGTGAATTGTTCCGCAAAGTGGTTAAAGAAGTCGGGGTGGCGATTATTGGCCAAACGGGCGATCTC
GTCCCTGCCGATAAACGCTTCTATTCTATTCGCGATAATACCGCCACCGTTGAATCCATTTCCCTCATCACTGCGTCGAT
TCTGTCTAAGAAATTAGCCTGTAATTTAGATGCGTTGGCGATGGACGTAAAAGTTGGTAGCGGCGCTTTCATGCCAACCT
ATGAGGCATCGGAAGAATTAGCTCGCAGTATCGCCGCCGTTGCAAATGGCGCGGGTACTAAAACGACGGCTTTACTTACC
GATATGAATCAAGTGCTTGCATCTTGTGCAGGTAACGCGGTTGAAGTGAAAGAAGCCATCGACTTTTTAACGGGTGCTTA
CCGTAACCCGCGTTTATATGAAGTCACTATGGGTCTTTGCGCTGAGATGTTGCTTCTGGGCGGTCTTGCAAGCAATGAAG
CCGATGCTCGCGCTAAACTGAATCGTGTACTCGATAATGGTCGCGCTGCAGAACTCTTTGGCAAGATGGTGTCGGGTCTT
GGTGGTCCGGTTGATTTTGTTGAAAACTACAGTAAATACCTACCACAGTCACAAATTATTCGCCCAGTTTTTGCCGATAT
GCAAGGTTATGCCTACAGCATGGATACCCGTGAGTTAGGTTTAGCGGTTGTGACCTTAGGTGGCGGCCGCCGTAAGCCCG
GCGATACACTAGACTATAGTGTTGGCTTAACCCAAGTGTGTGCCCTAGGCGATAAAGTGGATTCATCGACGCCGATTGCC
GTTATCCATGCACAGTCTGAAGCCGCCTTCGCGGAAGCGGAACTTGCGGTGAAAAAAGCGATTCACATTGGTGAAACCGC
TCCAGAAAAAACACCTGAGATCTATGCCTATATTCGTGCATCGGATCTTTAA

Upstream 100 bases:

>100_bases
TCGATAGTATGAACTTGTAATATTGCTACAGTTTTGATGTTTCATTGCAAAGATAAGCACTAGCGACAGGGTCGTTAGTG
TCTATCTTGGAGGCAGTATC

Downstream 100 bases:

>100_bases
GGAAGAATTATGAAACGTACCATTATTATGATGTTGGACTCCTTTGGAGTCGGTGCTTCTGCTGATGCAGCAAGCTTTGG
TGATGTCGGTTCCGATACCT

Product: thymidine phosphorylase

Products: NA

Alternate protein names: TdRPase [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MFLAQEIIRKKRNGLALSSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGP
VIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIQGYQTEPSSELFRKVVKEVGVAIIGQTGDL
VPADKRFYSIRDNTATVESISLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLT
DMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKLNRVLDNGRAAELFGKMVSGL
GGPVDFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELGLAVVTLGGGRRKPGDTLDYSVGLTQVCALGDKVDSSTPIA
VIHAQSEAAFAEAELAVKKAIHIGETAPEKTPEIYAYIRASDL

Sequences:

>Translated_443_residues
MFLAQEIIRKKRNGLALSSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGP
VIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIQGYQTEPSSELFRKVVKEVGVAIIGQTGDL
VPADKRFYSIRDNTATVESISLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLT
DMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKLNRVLDNGRAAELFGKMVSGL
GGPVDFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELGLAVVTLGGGRRKPGDTLDYSVGLTQVCALGDKVDSSTPIA
VIHAQSEAAFAEAELAVKKAIHIGETAPEKTPEIYAYIRASDL
>Mature_443_residues
MFLAQEIIRKKRNGLALSSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGP
VIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIQGYQTEPSSELFRKVVKEVGVAIIGQTGDL
VPADKRFYSIRDNTATVESISLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLT
DMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKLNRVLDNGRAAELFGKMVSGL
GGPVDFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELGLAVVTLGGGRRKPGDTLDYSVGLTQVCALGDKVDSSTPIA
VIHAQSEAAFAEAELAVKKAIHIGETAPEKTPEIYAYIRASDL

Specific function: The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis [H]

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI166158925, Length=443, Percent_Identity=37.4717832957111, Blast_Score=265, Evalue=9e-71,
Organism=Homo sapiens, GI4503445, Length=443, Percent_Identity=37.4717832957111, Blast_Score=265, Evalue=9e-71,
Organism=Homo sapiens, GI166158922, Length=443, Percent_Identity=37.4717832957111, Blast_Score=265, Evalue=9e-71,
Organism=Escherichia coli, GI1790842, Length=438, Percent_Identity=67.5799086757991, Blast_Score=611, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR013102
- InterPro:   IPR018090
- InterPro:   IPR000053
- InterPro:   IPR017872
- InterPro:   IPR013465 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF07831 PYNP_C [H]

EC number: =2.4.2.4 [H]

Molecular weight: Translated: 46951; Mature: 46951

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAQEIIRKKRNGLALSSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALT
CCHHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEEEE
TAMRDSGTVLNWQSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHT
EEECCCCCEEEEHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
GGTLDKFDAIQGYQTEPSSELFRKVVKEVGVAIIGQTGDLVPADKRFYSIRDNTATVESI
CCCCHHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCCHHHHH
SLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLT
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
DMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKL
HHHHHHHHHCCCCEEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHH
NRVLDNGRAAELFGKMVSGLGGPVDFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELG
HHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCHHCC
LAVVTLGGGRRKPGDTLDYSVGLTQVCALGDKVDSSTPIAVIHAQSEAAFAEAELAVKKA
EEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
IHIGETAPEKTPEIYAYIRASDL
HHCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MFLAQEIIRKKRNGLALSSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALT
CCHHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEEEE
TAMRDSGTVLNWQSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHT
EEECCCCCEEEEHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
GGTLDKFDAIQGYQTEPSSELFRKVVKEVGVAIIGQTGDLVPADKRFYSIRDNTATVESI
CCCCHHHHHCCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCCHHHHH
SLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLT
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
DMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKL
HHHHHHHHHCCCCEEHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHCCCCCCCHHHHHHH
NRVLDNGRAAELFGKMVSGLGGPVDFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELG
HHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEECCCHHCC
LAVVTLGGGRRKPGDTLDYSVGLTQVCALGDKVDSSTPIAVIHAQSEAAFAEAELAVKKA
EEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHH
IHIGETAPEKTPEIYAYIRASDL
HHCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA