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The map label for this gene is serB [H]

Identifier: 160876467

GI number: 160876467

Start: 3969376

End: 3970356

Strand: Reverse

Name: serB [H]

Synonym: Sbal195_3361

Alternate gene names: 160876467

Gene position: 3970356-3969376 (Counterclockwise)

Preceding gene: 160876469

Following gene: 160876466

Centisome position: 74.25

GC content: 50.36

Gene sequence:

>981_bases
ATGGAAAGCTTGAACCAAGATGCGCTTTTTTTGTGGTTAGTCTCTGACCATTCCCCAAGGTTTGAACGCCAAGGGCAAGT
GTTTGAACGTTATCAAGAGTCAGCAAACCGCGCTGGTGTTTCGCGTTTGCGGATTATCTATCAAGATACGTTAGCGCAGG
CAGCGATATCGGCCTGGATTGCGGCATTGCCTTCGTCTGACGTTATCGGTATTGCCCATATCAAACGCCAAGTTGGCTTA
CATTGTATCGAGTTGGCGCTGGTGAATGTGCCTTCTCAGGCACAGTTAGCGGCGTTCCCTCAGTCTTTGGCTGAACTGCA
TGTGCTCCATGTTGATTTGCCTCGCTTGAATCATCCCGGCTTATTAGTGATGGACATGGATTCCACGGCGATTCAGATTG
AATGTATTGATGAATTAGCGGCCATGGCGGGTGTTGGCGAGCGCGTGGCGGCGATTACTGAACGTGCTATGCAAGGTGAG
CTAGATTTTGAGCAGAGTCTGCGTCAGCGCGTGGCACAGCTTAAGGGCGCCGATGCCAGTATTATCACGACCTTGTGCGA
CAACTTGCCTTTAATGCCTGGGCTTGAGTCCATACTGTTAGAACTTAAATCCCATGACTGGCGTTTAGTGGTGGCATCTG
GCGGCTTTACGCCTTTTGTGGGTCATTTAAAACAGCTTCTAAGCTTAGATGCGGCCTTTGCTAATGAGTTAGTCATCACT
GATGGCAAACTCGCGGGTGAAGTGACCGGTAAAGTCGTGGATGCGCAGTTTAAAGCGGATGTGGTTGAGCGTTGCAGTGA
GCAGTGGGACATTCAAAAAGGTCAAAGCGTCGCTATCGGCGATGGCGCGAATGATATCCCTATGGTGATGGCGGCGGATT
TTGGTATCGCTTTCCATGCCAAACCTAAGCTGGCAGCCGCGGCGGATGCCAATATTCGCCATCTTGACCTGCGCGTTTTA
CCTTATCTGTTGCAAATCTAG

Upstream 100 bases:

>100_bases
TAGCCCTTTAAGATATAACACTTTGACCCTTAAAATGTAGAGCGCTTGCCTAATCATAATTGATTCTGAGTGAGCCCGAT
AGTTGGAGAATTTAAGTCCG

Downstream 100 bases:

>100_bases
GTTATTCATTTATTTGAAATTTGAGTCGAGATGAAAGTCTAAGTAAGGGCTGAGTTAGAGTAATGACTCTTGTCTTTTAT
CGATGAACTGGTAGTTTAGG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESANRAGVSRLRIIYQDTLAQAAISAWIAALPSSDVIGIAHIKRQVGL
HCIELALVNVPSQAQLAAFPQSLAELHVLHVDLPRLNHPGLLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGE
LDFEQSLRQRVAQLKGADASIITTLCDNLPLMPGLESILLELKSHDWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
DGKLAGEVTGKVVDAQFKADVVERCSEQWDIQKGQSVAIGDGANDIPMVMAADFGIAFHAKPKLAAAADANIRHLDLRVL
PYLLQI

Sequences:

>Translated_326_residues
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESANRAGVSRLRIIYQDTLAQAAISAWIAALPSSDVIGIAHIKRQVGL
HCIELALVNVPSQAQLAAFPQSLAELHVLHVDLPRLNHPGLLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGE
LDFEQSLRQRVAQLKGADASIITTLCDNLPLMPGLESILLELKSHDWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
DGKLAGEVTGKVVDAQFKADVVERCSEQWDIQKGQSVAIGDGANDIPMVMAADFGIAFHAKPKLAAAADANIRHLDLRVL
PYLLQI
>Mature_326_residues
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESANRAGVSRLRIIYQDTLAQAAISAWIAALPSSDVIGIAHIKRQVGL
HCIELALVNVPSQAQLAAFPQSLAELHVLHVDLPRLNHPGLLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGE
LDFEQSLRQRVAQLKGADASIITTLCDNLPLMPGLESILLELKSHDWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
DGKLAGEVTGKVVDAQFKADVVERCSEQWDIQKGQSVAIGDGANDIPMVMAADFGIAFHAKPKLAAAADANIRHLDLRVL
PYLLQI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=197, Percent_Identity=31.4720812182741, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1790849, Length=205, Percent_Identity=59.0243902439024, Blast_Score=251, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI115534456, Length=186, Percent_Identity=29.5698924731183, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115534454, Length=186, Percent_Identity=29.5698924731183, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=222, Percent_Identity=40.0900900900901, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35492; Mature: 35492

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESANRAGVSRLRIIYQDTLAQAAISAWI
CCCCCCCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AALPSSDVIGIAHIKRQVGLHCIELALVNVPSQAQLAAFPQSLAELHVLHVDLPRLNHPG
HHCCCCCCCHHHHHHHHHCHHEEEHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCC
LLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGELDFEQSLRQRVAQLKGADAS
EEEEECCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
IITTLCDNLPLMPGLESILLELKSHDWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
HHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
DGKLAGEVTGKVVDAQFKADVVERCSEQWDIQKGQSVAIGDGANDIPMVMAADFGIAFHA
CCCCCCHHHCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCEEEEC
KPKLAAAADANIRHLDLRVLPYLLQI
CCCEEECCCCCCEEEHHHHHHHHHCC
>Mature Secondary Structure
MESLNQDALFLWLVSDHSPRFERQGQVFERYQESANRAGVSRLRIIYQDTLAQAAISAWI
CCCCCCCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
AALPSSDVIGIAHIKRQVGLHCIELALVNVPSQAQLAAFPQSLAELHVLHVDLPRLNHPG
HHCCCCCCCHHHHHHHHHCHHEEEHHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCC
LLVMDMDSTAIQIECIDELAAMAGVGERVAAITERAMQGELDFEQSLRQRVAQLKGADAS
EEEEECCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHH
IITTLCDNLPLMPGLESILLELKSHDWRLVVASGGFTPFVGHLKQLLSLDAAFANELVIT
HHHHHHHCCCCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEE
DGKLAGEVTGKVVDAQFKADVVERCSEQWDIQKGQSVAIGDGANDIPMVMAADFGIAFHA
CCCCCCHHHCCEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEECCCEEEEC
KPKLAAAADANIRHLDLRVLPYLLQI
CCCEEECCCCCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]