Click here to switch to the map view.

The map label for this gene is ribD [H]

Identifier: 160876409

GI number: 160876409

Start: 3893306

End: 3894460

Strand: Reverse

Name: ribD [H]

Synonym: Sbal195_3303

Alternate gene names: 160876409

Gene position: 3894460-3893306 (Counterclockwise)

Preceding gene: 160876410

Following gene: 160876408

Centisome position: 72.83

GC content: 50.91

Gene sequence:

>1155_bases
ATGAGCTTGAACATAAGTTGGTCTGTACTCGATACACAAATGATGAGCCGCGCGATTCAATTAGCGCGCAAAGGCTTTTA
CACCACGAGACCCAATCCCTGTGTGGGCTGCGTTATCGTTAAAGATAACCAGATTGTTGGCGAAGGTTATCATCAAAAAG
CGGGTGAACCCCACGCCGAAGTGCATGCGCTACGTATGGCAGGTGAACACGCCCGCGGCGCAACGGCCTATGTCACCTTA
GAGCCCTGCAGCCATTATGGCCGCACGCCGCCCTGCGCCTTGGCGCTGATCAATATTGGCGTTAAACGTGTGGTGGTAGC
GGTTGAAGATCCTAATCCGCAAGTCGGTGGTCGCGGTATTCAAATGCTGCGCGACGCAGGTATTGAAGTGGATGTGGGAT
TACATCGCGATGAAGCCTATGCCTTGAATTTAGGCTTTATGAAGCGGATGGAATCGGGTTTACCCAGAGTTACAGTCAAA
TTGGCTGCGAGTCTTGATGGTAAAACCGCGCTGTCTAACGGTGTGTCTAAATGGATTACCGGGCCTGAATCTCGCCGCGA
CGTGCAGCGCTTACGCTTACGTTCCTGCGCGTTGGTGACTGGGATTGAAACCATACTGGCGGACGATCCCTCACTCAATG
TGCGATATCAAGAACTTGGTGGCTTGAAAGACAGCGTAACCGAGGCGCAATTACTGCAGCCGTTAAGAGTGATACTCGAC
AGTCGCGCCCGTTTGCCCTTATCGGCCGCATGTTTGGCTATCGTATCGCCGATACTCTTGGTCTCGACCGTGGCTTATCC
CGCAGAGTTTCAAGCACAATTGCCCTCCCATGTGAGTTGCCTCGTGTTACCTGCAATTGCAGGTCGCGTATCCTTACCTG
AACTATTAAGCTATTTAGGCCAAAGCTGTAATCACGTGCTAGTGGAAGCGGGTGCAACCTTAGCGGGCGCTTTTTTAGCA
GAGGGGCTGGCCGATGAATTAGTGCTGTACCAAGCGATGAAAATCCTCGGTGGGCAAGGGCGTAATCTATTGCAGCTACC
CGATTATCAAACCATGGCGCAAATTCCTGCATTAACTTTGGTCGATGAGCGCAAATTAGGGCCAGATACCCGTTTAATCT
TGAGCGTTAAGCTTGATACTTCTTTATTTAATTAA

Upstream 100 bases:

>100_bases
CGTTTTGCTTCTGTGTACCGTGCCTTTGAAGACGTATCTGAATTTGGTGAGGCCATCGCTAAACTGCAAAAGTAGTTATT
CGACTAACATAGGGTTGAAC

Downstream 100 bases:

>100_bases
GTGAGTTAACCATGTTTACTGGGATTATTGAAGCCGTTGGCACCCTGCGCAAACTGGAGCGTAAAGGCGAGGATATTCGT
CTTACCGTGGCGAGTGGCAA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSLNISWSVLDTQMMSRAIQLARKGFYTTRPNPCVGCVIVKDNQIVGEGYHQKAGEPHAEVHALRMAGEHARGATAYVTL
EPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVGGRGIQMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVK
LAASLDGKTALSNGVSKWITGPESRRDVQRLRLRSCALVTGIETILADDPSLNVRYQELGGLKDSVTEAQLLQPLRVILD
SRARLPLSAACLAIVSPILLVSTVAYPAEFQAQLPSHVSCLVLPAIAGRVSLPELLSYLGQSCNHVLVEAGATLAGAFLA
EGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALTLVDERKLGPDTRLILSVKLDTSLFN

Sequences:

>Translated_384_residues
MSLNISWSVLDTQMMSRAIQLARKGFYTTRPNPCVGCVIVKDNQIVGEGYHQKAGEPHAEVHALRMAGEHARGATAYVTL
EPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVGGRGIQMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVK
LAASLDGKTALSNGVSKWITGPESRRDVQRLRLRSCALVTGIETILADDPSLNVRYQELGGLKDSVTEAQLLQPLRVILD
SRARLPLSAACLAIVSPILLVSTVAYPAEFQAQLPSHVSCLVLPAIAGRVSLPELLSYLGQSCNHVLVEAGATLAGAFLA
EGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALTLVDERKLGPDTRLILSVKLDTSLFN
>Mature_383_residues
SLNISWSVLDTQMMSRAIQLARKGFYTTRPNPCVGCVIVKDNQIVGEGYHQKAGEPHAEVHALRMAGEHARGATAYVTLE
PCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVGGRGIQMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVKL
AASLDGKTALSNGVSKWITGPESRRDVQRLRLRSCALVTGIETILADDPSLNVRYQELGGLKDSVTEAQLLQPLRVILDS
RARLPLSAACLAIVSPILLVSTVAYPAEFQAQLPSHVSCLVLPAIAGRVSLPELLSYLGQSCNHVLVEAGATLAGAFLAE
GLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALTLVDERKLGPDTRLILSVKLDTSLFN

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=372, Percent_Identity=51.0752688172043, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI145693172, Length=152, Percent_Identity=34.8684210526316, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41397; Mature: 41265

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNISWSVLDTQMMSRAIQLARKGFYTTRPNPCVGCVIVKDNQIVGEGYHQKAGEPHAE
CCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEECCCCHHCCCCCHHH
VHALRMAGEHARGATAYVTLEPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVGGRGI
HHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCHHH
QMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVKLAASLDGKTALSNGVSKWIT
HHHHHCCCEEEEECCCCCEEEECHHHHHHHHCCCCEEEEEEEECCCCHHHHHHCHHHHCC
GPESRRDVQRLRLRSCALVTGIETILADDPSLNVRYQELGGLKDSVTEAQLLQPLRVILD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHC
SRARLPLSAACLAIVSPILLVSTVAYPAEFQAQLPSHVSCLVLPAIAGRVSLPELLSYLG
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
QSCNHVLVEAGATLAGAFLAEGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALTL
HCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCEEE
VDERKLGPDTRLILSVKLDTSLFN
ECCCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SLNISWSVLDTQMMSRAIQLARKGFYTTRPNPCVGCVIVKDNQIVGEGYHQKAGEPHAE
CEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEECCCCHHCCCCCHHH
VHALRMAGEHARGATAYVTLEPCSHYGRTPPCALALINIGVKRVVVAVEDPNPQVGGRGI
HHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCCCHHH
QMLRDAGIEVDVGLHRDEAYALNLGFMKRMESGLPRVTVKLAASLDGKTALSNGVSKWIT
HHHHHCCCEEEEECCCCCEEEECHHHHHHHHCCCCEEEEEEEECCCCHHHHHHCHHHHCC
GPESRRDVQRLRLRSCALVTGIETILADDPSLNVRYQELGGLKDSVTEAQLLQPLRVILD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHC
SRARLPLSAACLAIVSPILLVSTVAYPAEFQAQLPSHVSCLVLPAIAGRVSLPELLSYLG
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHH
QSCNHVLVEAGATLAGAFLAEGLADELVLYQAMKILGGQGRNLLQLPDYQTMAQIPALTL
HCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHCCCEEE
VDERKLGPDTRLILSVKLDTSLFN
ECCCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]