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The map label for this gene is ltaE [H]

Identifier: 160876275

GI number: 160876275

Start: 3743820

End: 3744833

Strand: Reverse

Name: ltaE [H]

Synonym: Sbal195_3169

Alternate gene names: 160876275

Gene position: 3744833-3743820 (Counterclockwise)

Preceding gene: 160876279

Following gene: 160876274

Centisome position: 70.03

GC content: 49.9

Gene sequence:

>1014_bases
ATGATAGATTTACGCAGTGATACTGTTACCCAGCCAACAGCAGCGATGCGATTAGCCATGTCCAGAGCCGAAGTAGGTGA
CGATGTTTACGGTGATGATCCCACGGTAAATAGTCTGCAGGATATGGCTGCAGAGATGTTTGGCTTTGAAAGCGCATTAT
TTACCTGTTCGGGTACGCAGGCGAATTTATTGGCTTTGATGGCCCACTGTGAGCGTGGTGATGAGTATCTGTGCGGCCAG
CAGGCCCATAACTATAAATTTGAGGGTGGCGGTGCCGCTGTCTTAGGCAGCATTCAACCTCAACCTTTGTTGAATCAAGT
CGATGGCACCATTGCCTTGGCCGATATTGAAGCCGCCATTAAGCCTGACGATATCCACTTTGCCCGCACGCGTTTGCTCA
GTTTAGAGAATACGATTGGCGGTAAAGTGATCCCGCAAAGCTATTTAGCGGACGCGCAGGCTCTGGCCTTTAATCGCGGG
TTAAAAATCCATCTCGACGGCGCACGAGTTGCTAATGCGGCTGTGGCGCAGAATATCGCGATAAGTAAGATTACGGCGCA
TTTTGATTCTGTGTCGATTTGTCTGTCCAAAGGGTTATGCGCGCCAGTTGGCTCATTACTCTTAGGTGACGAGCGTTTGA
TTAAGAAGGCGATACGCTGGCGTAAAATGCTAGGTGGCGGCATGCGTCAAGCTGGGATACTTGCTGCGGCAGGTAAGCTC
GCCTTAACTGAGCAAGTGCAACGACTGAGTGAAGATCATGACAACGCGGCGTATTTGGCTCGCCAGTTGGCAGAGTTGAG
TGAGTTCGACGTCGATTTAGCCGCAGTACAAACCAATATGTTATTTGCCAAATTAGCGCCTAAAGTTGATGCGGTTTTAT
TGGCGAAACACTGTCGAGCTGAAGGCATTCTAATAAGCCCTGGGCGCACGATTCGGCTTGTGACTCACAACGATGTGAGC
CGTCAGGACATAGATAAAGTGTTGCGGGTTATGAAGCAGCACTTCACCGCCTAA

Upstream 100 bases:

>100_bases
ACATGATGAATAAGCATGATGATAAACTATACAAAATAAGCCTTTGGCGCTAGAGTCTTGAGCCCATTAAGCGCCAACCA
AACCTTAAGTTGAGGACGAG

Downstream 100 bases:

>100_bases
GCGCTGCTTGTTTTAAAACCTCTAAATGCCCGGGCTTTGTCTCGGGCATTTTTATTTGCGGGTATAACTTGATGTTGAAT
TATTGAGCAATTAACTGTTG

Product: threonine aldolase

Products: NA

Alternate protein names: Low-specificity L-TA [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIDLRSDTVTQPTAAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTCSGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLLNQVDGTIALADIEAAIKPDDIHFARTRLLSLENTIGGKVIPQSYLADAQALAFNRG
LKIHLDGARVANAAVAQNIAISKITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
ALTEQVQRLSEDHDNAAYLARQLAELSEFDVDLAAVQTNMLFAKLAPKVDAVLLAKHCRAEGILISPGRTIRLVTHNDVS
RQDIDKVLRVMKQHFTA

Sequences:

>Translated_337_residues
MIDLRSDTVTQPTAAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTCSGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLLNQVDGTIALADIEAAIKPDDIHFARTRLLSLENTIGGKVIPQSYLADAQALAFNRG
LKIHLDGARVANAAVAQNIAISKITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
ALTEQVQRLSEDHDNAAYLARQLAELSEFDVDLAAVQTNMLFAKLAPKVDAVLLAKHCRAEGILISPGRTIRLVTHNDVS
RQDIDKVLRVMKQHFTA
>Mature_337_residues
MIDLRSDTVTQPTAAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTCSGTQANLLALMAHCERGDEYLCGQ
QAHNYKFEGGGAAVLGSIQPQPLLNQVDGTIALADIEAAIKPDDIHFARTRLLSLENTIGGKVIPQSYLADAQALAFNRG
LKIHLDGARVANAAVAQNIAISKITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
ALTEQVQRLSEDHDNAAYLARQLAELSEFDVDLAAVQTNMLFAKLAPKVDAVLLAKHCRAEGILISPGRTIRLVTHNDVS
RQDIDKVLRVMKQHFTA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. L-threo-phenylserine and L- erythro-phenylserine are also good substrates [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=327, Percent_Identity=58.7155963302752, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI193206524, Length=342, Percent_Identity=43.2748538011696, Blast_Score=248, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI193206522, Length=342, Percent_Identity=43.2748538011696, Blast_Score=248, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI193206520, Length=342, Percent_Identity=43.2748538011696, Blast_Score=248, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6320789, Length=339, Percent_Identity=37.4631268436578, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21355439, Length=305, Percent_Identity=47.5409836065574, Blast_Score=258, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 36273; Mature: 36273

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLRSDTVTQPTAAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTCSGTQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHEEEECCCH
ANLLALMAHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLLNQVDGTIALADIEAAI
HHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEECCCCCCHHHHHCCCEEEEEEEHHHC
KPDDIHFARTRLLSLENTIGGKVIPQSYLADAQALAFNRGLKIHLDGARVANAAVAQNIA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
ISKITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHH
ALTEQVQRLSEDHDNAAYLARQLAELSEFDVDLAAVQTNMLFAKLAPKVDAVLLAKHCRA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
EGILISPGRTIRLVTHNDVSRQDIDKVLRVMKQHFTA
CCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDLRSDTVTQPTAAMRLAMSRAEVGDDVYGDDPTVNSLQDMAAEMFGFESALFTCSGTQ
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHEEEECCCH
ANLLALMAHCERGDEYLCGQQAHNYKFEGGGAAVLGSIQPQPLLNQVDGTIALADIEAAI
HHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEECCCCCCHHHHHCCCEEEEEEEHHHC
KPDDIHFARTRLLSLENTIGGKVIPQSYLADAQALAFNRGLKIHLDGARVANAAVAQNIA
CCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHH
ISKITAHFDSVSICLSKGLCAPVGSLLLGDERLIKKAIRWRKMLGGGMRQAGILAAAGKL
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCHH
ALTEQVQRLSEDHDNAAYLARQLAELSEFDVDLAAVQTNMLFAKLAPKVDAVLLAKHCRA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
EGILISPGRTIRLVTHNDVSRQDIDKVLRVMKQHFTA
CCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]