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The map label for this gene is atoC [H]

Identifier: 160876179

GI number: 160876179

Start: 3641919

End: 3643262

Strand: Reverse

Name: atoC [H]

Synonym: Sbal195_3070

Alternate gene names: 160876179

Gene position: 3643262-3641919 (Counterclockwise)

Preceding gene: 160876180

Following gene: 160876178

Centisome position: 68.13

GC content: 46.43

Gene sequence:

>1344_bases
ATGTCTGAAGCAAAGTTATTGCTCGTTGAAGATGATGCCTCATTGCGTGAAGCCTTGTTGGATACCTTAATGTTGGCTCA
ATATGAGTGCATTGATGTTGCCTCCGGTGAAGACGCTATCTTAGCTTTGAAACAACATCAATTTGATTTAGTCATTAGCG
ATGTGCAGATGCAAGGTATTGGTGGTTTAGGATTATTAAACTTCCTACAGCAACATCATCCTAAGTTGCCAGTGTTGTTG
ATGACAGCTTATGCCACGATTGGTAGTGCGGTGGATGCTATTAAATTGGGCGCTGTCGATTACTTAGCGAAACCTTTTGC
GCCAGAAGTCTTGCTCAATCAAGTTTCCCGCTATTTGCCGTTAAAACAAAATGTGGATCAGCCAGTTGTTGCCGATGAGA
AGAGTTTAGCTTTATTGGCACTGGCTCAGCGGGTTGCCGCTTCCGATGCCTCTGTTATGATCTTAGGTCCTAGCGGCTCG
GGTAAAGAAGTCTTAGCCCGTTATATTCATCAACACAGTAGCCGTGCCGATCAAGCTTTTGTGGCCATTAACTGTGCAGC
GATTCCTGAGAATATGCTCGAAGCCACTCTTTTTGGTTATGAAAAAGGCGCATTTACTGGTGCCTATCAAGCGTGTCCGG
GGAAATTTGAGCAGGCTCAAGGTGGCACTTTGCTGCTAGATGAAATCTCTGAGATGGATTTAGGCCTACAAGCTAAGTTA
TTGCGGGTATTGCAAGAGCGTGAAGTTGAGCGTTTAGGCGGCCGTAAAATCATTAAGCTCGATGTGCGCGTGCTTGCCAC
ATCCAATCGCGACTTAAAAGCCGTGGTAGCCGCTGGTGGATTTAGGGAAGATCTCTATTATCGAATCAACGTGTTCCCCT
TAGCTTGGCCCGCATTAAGTCAACGTCCAGCGGATATTCTGCCCCTTGCGCGCCATTTACTGGTTAAGCATGCCAAGGCA
TTGAATGTCGCCGATGTGCCTGAGTTGGATGAAAATGCACGTCGACGTTTATTGAGTCATCGCTGGCCGGGGAACGTACG
TGAACTCGATAATGTGATCCAGCGGGCTTTGATATTAAGAGCCGGTCAAGTGATCACCGCCAATGACATTATTATTGATG
CGCAGGATGTGATTTTAGGCGCTGAAGACCTAGATCAATTTGTTGCCGAGCCAGACGGTTTAGGCGAAGAGCTTAAAGCG
CAGGAGCATGTGATTATTTTAGAAACCCTTAATCAATGCCAAGGAAGTCGCAAGCTGGTCGCTGAAAAACTGGGGATAAG
TGCCCGAACCTTAAGATACAAGATGGCAAGAATGCGTGATATGGGCATTCAACTGCCAAATTAG

Upstream 100 bases:

>100_bases
GGACAACTGCAATTAAGTTGCTTACCGAATAAAGGTTGCACTGTGTCTTTAGTCTTCCCAAGGGCTAAATCTGCGGTGAT
ATTACCTTTGGAGATTACCC

Downstream 100 bases:

>100_bases
CCTTTAAATTCAAGTGATAATCTTGCAGCCTCCACATGAGTGTGAGGCTGCATTTATTAAAATATACTACCGCAAAAGTG
GCCTATTTTATCCAGAATCC

Product: Fis family two component sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSEAKLLLVEDDASLREALLDTLMLAQYECIDVASGEDAILALKQHQFDLVISDVQMQGIGGLGLLNFLQQHHPKLPVLL
MTAYATIGSAVDAIKLGAVDYLAKPFAPEVLLNQVSRYLPLKQNVDQPVVADEKSLALLALAQRVAASDASVMILGPSGS
GKEVLARYIHQHSSRADQAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEISEMDLGLQAKL
LRVLQEREVERLGGRKIIKLDVRVLATSNRDLKAVVAAGGFREDLYYRINVFPLAWPALSQRPADILPLARHLLVKHAKA
LNVADVPELDENARRRLLSHRWPGNVRELDNVIQRALILRAGQVITANDIIIDAQDVILGAEDLDQFVAEPDGLGEELKA
QEHVIILETLNQCQGSRKLVAEKLGISARTLRYKMARMRDMGIQLPN

Sequences:

>Translated_447_residues
MSEAKLLLVEDDASLREALLDTLMLAQYECIDVASGEDAILALKQHQFDLVISDVQMQGIGGLGLLNFLQQHHPKLPVLL
MTAYATIGSAVDAIKLGAVDYLAKPFAPEVLLNQVSRYLPLKQNVDQPVVADEKSLALLALAQRVAASDASVMILGPSGS
GKEVLARYIHQHSSRADQAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEISEMDLGLQAKL
LRVLQEREVERLGGRKIIKLDVRVLATSNRDLKAVVAAGGFREDLYYRINVFPLAWPALSQRPADILPLARHLLVKHAKA
LNVADVPELDENARRRLLSHRWPGNVRELDNVIQRALILRAGQVITANDIIIDAQDVILGAEDLDQFVAEPDGLGEELKA
QEHVIILETLNQCQGSRKLVAEKLGISARTLRYKMARMRDMGIQLPN
>Mature_446_residues
SEAKLLLVEDDASLREALLDTLMLAQYECIDVASGEDAILALKQHQFDLVISDVQMQGIGGLGLLNFLQQHHPKLPVLLM
TAYATIGSAVDAIKLGAVDYLAKPFAPEVLLNQVSRYLPLKQNVDQPVVADEKSLALLALAQRVAASDASVMILGPSGSG
KEVLARYIHQHSSRADQAFVAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEISEMDLGLQAKLL
RVLQEREVERLGGRKIIKLDVRVLATSNRDLKAVVAAGGFREDLYYRINVFPLAWPALSQRPADILPLARHLLVKHAKAL
NVADVPELDENARRRLLSHRWPGNVRELDNVIQRALILRAGQVITANDIIIDAQDVILGAEDLDQFVAEPDGLGEELKAQ
EHVIILETLNQCQGSRKLVAEKLGISARTLRYKMARMRDMGIQLPN

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=447, Percent_Identity=41.6107382550336, Blast_Score=324, Evalue=8e-90,
Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=39.4618834080717, Blast_Score=287, Evalue=9e-79,
Organism=Escherichia coli, GI1790299, Length=479, Percent_Identity=35.9081419624217, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1788905, Length=375, Percent_Identity=42.1333333333333, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI87082117, Length=307, Percent_Identity=45.6026058631922, Blast_Score=248, Evalue=7e-67,
Organism=Escherichia coli, GI1789087, Length=322, Percent_Identity=43.4782608695652, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789233, Length=307, Percent_Identity=41.042345276873, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI87081872, Length=303, Percent_Identity=37.6237623762376, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=47.6190476190476, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=222, Percent_Identity=45.945945945946, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1787583, Length=320, Percent_Identity=35.625, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=37.2384937238494, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI87081858, Length=228, Percent_Identity=32.0175438596491, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790552, Length=107, Percent_Identity=35.5140186915888, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=35.3448275862069, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49032; Mature: 48901

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKLLLVEDDASLREALLDTLMLAQYECIDVASGEDAILALKQHQFDLVISDVQMQGI
CCCCEEEEEECCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCEEEEEEEEEECCC
GGLGLLNFLQQHHPKLPVLLMTAYATIGSAVDAIKLGAVDYLAKPFAPEVLLNQVSRYLP
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
LKQNVDQPVVADEKSLALLALAQRVAASDASVMILGPSGSGKEVLARYIHQHSSRADQAF
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEE
VAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEISEMDLGLQAKL
EEEEEHHCCHHHHHHHHHCCCCCCCCCCHHCCCCCCHHCCCCEEEEHHHHHCCCCHHHHH
LRVLQEREVERLGGRKIIKLDVRVLATSNRDLKAVVAAGGFREDLYYRINVFPLAWPALS
HHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEECHHHC
QRPADILPLARHLLVKHAKALNVADVPELDENARRRLLSHRWPGNVRELDNVIQRALILR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGQVITANDIIIDAQDVILGAEDLDQFVAEPDGLGEELKAQEHVIILETLNQCQGSRKLV
CCCEEEECCEEEEHHHHEECHHHHHHHHCCCCCCCHHHCCCCCEEEEEHHHHCCCHHHHH
AEKLGISARTLRYKMARMRDMGIQLPN
HHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEAKLLLVEDDASLREALLDTLMLAQYECIDVASGEDAILALKQHQFDLVISDVQMQGI
CCCEEEEEECCHHHHHHHHHHHHHHHHHEEEECCCCCCEEEEECCCEEEEEEEEEECCC
GGLGLLNFLQQHHPKLPVLLMTAYATIGSAVDAIKLGAVDYLAKPFAPEVLLNQVSRYLP
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
LKQNVDQPVVADEKSLALLALAQRVAASDASVMILGPSGSGKEVLARYIHQHSSRADQAF
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEE
VAINCAAIPENMLEATLFGYEKGAFTGAYQACPGKFEQAQGGTLLLDEISEMDLGLQAKL
EEEEEHHCCHHHHHHHHHCCCCCCCCCCHHCCCCCCHHCCCCEEEEHHHHHCCCCHHHHH
LRVLQEREVERLGGRKIIKLDVRVLATSNRDLKAVVAAGGFREDLYYRINVFPLAWPALS
HHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEEEECCCCCCCEEEEEEEEEEECHHHC
QRPADILPLARHLLVKHAKALNVADVPELDENARRRLLSHRWPGNVRELDNVIQRALILR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AGQVITANDIIIDAQDVILGAEDLDQFVAEPDGLGEELKAQEHVIILETLNQCQGSRKLV
CCCEEEECCEEEEHHHHEECHHHHHHHHCCCCCCCHHHCCCCCEEEEEHHHHCCCHHHHH
AEKLGISARTLRYKMARMRDMGIQLPN
HHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]