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The map label for this gene is cheA [H]

Identifier: 160876157

GI number: 160876157

Start: 3619175

End: 3621391

Strand: Reverse

Name: cheA [H]

Synonym: Sbal195_3048

Alternate gene names: 160876157

Gene position: 3621391-3619175 (Counterclockwise)

Preceding gene: 160876158

Following gene: 160876156

Centisome position: 67.72

GC content: 46.73

Gene sequence:

>2217_bases
ATGGCCTTTGATGTAGATGAAGAGATACTCCAGGACTTTTTAATCGAAGCCGGTGAAATTTTAGAGCTTCTGCAAGAGCA
ACTCGTTGCGCTTGAAAATAATCCTGATGACACAAACTTGCTAAACGCCATTTTCCGAGGGTTCCATACCGTTAAAGGTG
GCGCAGGCTTTCTTAGCTTAACTCCCATGGTCGATGTGTGTCATGAGGCTGAAAATACCTTCGATCTATTGCGCACAGGC
AAACGCAGCGTAAATGCAGAGCTGATGGATATTATTTTGCAGGCTGTTGATGCTATTAATACCATGTTTGCTCAAACGCA
GCAGGGCGAACAACAAGATCCTGCTGAGTCAGGCCTGTTGTCTAGACTTAAAATGCTGAGTTCAGGTGCGCCATTGCCAT
CTGAAGTTGCGTCTGCAGAGGTGGTAGAAGTTGTCGAACCAGAGCCTGTCGTTGAAGCCATTGTTGAAACTCCCGTCCCA
CAAGACATTCCCGTAGAGATAAGTAATAGCTCATCTTCAAGTATTGATGATATAAACGATGCTGAATTTGAAGCCTTGTT
AGATGCGCTTCATGGCTCAGGAAAAGGCCCTGCGGCTGCTACCGCTGTGGCGTCTGAACCTGTGGTTGCTAAGCCAGCTG
CGCCAGTTAAAGCGCCTTCAGCATCGGGTGATGACATCACTGATGATGAGTTTGAGGCATTGCTTGATGAGCTGCATGGT
TCAGGCAAGTTTAAAGCTGAGGCAGAAGTGCCGGCTAAACCAAAGGTCGCTTCGGCTCCCACGCCTCAACCGATAGTGGA
TGCCGATGAAATTACCGATGACGAGTTTGAAAGATTACTCGATGAACTCCATGGGAAAGGTGCAGCCCCTGCAAAAGCAG
AAGTAAAAGCGCCTACTGCACCAGTAACGCCTGCTTCGACTGCTGCACCTAAAGCCGCTGCGCCTGCTCCAGCTCCCGTT
GTTGCCGCAAAACCGAAAGTGGACATAGCTGTTGTAGAGAAAGCGCCAGCTAAAGCAAGTTCAGCAAATGTGCCTCAAGG
TGAAACGACAGTACGTGTTGATACTGCACGACTCGACCAAATCATGAATATGGTGGGCGAGTTAGTGTTAGTGCGTAATC
GATTAGTGAGCTTAGGTATCAGTCGTGATGATGAGGAAATGTCTAAGGCCCTTGCGAACTTAGATCTCGTGACTGCCGAT
TTGCAAGGCGCGGTGATGAAAACCCGTATGCAACCGATCAAGAAAGTGTTTGGTCGTTTCCCTCGGGTAGTACGTGATCT
TGCGCGTACACTCAATAAAGAAATTGATTTGATCATGGTCGGTGAAGAAACCGACCTAGATAAAAACTTAGTTGAAGCGC
TTGCCGATCCACTCGTCCACTTAGTGCGTAACTCGGTGGATCACGGTATTGAAATGCCAAATGAGCGTGAAGCCAACGGC
AAGCCGAGAACGGGTACGATTACCTTATCTGCAAGTCAGGAAGGTGACCATATACTGCTAAAAATCGAAGACGATGGCGC
AGGTATGGACCCTGAAAAACTGAAAAAGATCGCGATAACGCGTGGTGTGCTTGATGAAGATTCAGCTTCGCGAATGACTG
ACAGCGAAGCGTATAATTTGATTTTTGCGCCCGGTTTTTCGACTAAGGTCGAGATTTCAGATATTTCTGGTCGTGGCGTT
GGGATGGACGTGGTAAAAACCCGTATCACTCAGCTTAACGGCACAGTGCATATTGATTCTATGAAAGGTAAGGGCACGAT
ACTTGAGATTAAAGTACCGTTAACGCTGGCGATTATGCCAACCTTAATGGTTGATGTCGCTAAACAAGTGTTTGCATTAC
CTCTGTCTAGCGTGAACGAGATATTTCATCTCGATCTTACTAAGACCAATATCGTCGATGGACAACTCACCGTCATAGTG
CGTAACAAGGCTGTGCCTTTGTTCTATTTGGAGCATTGGCTGCATAGAAATAAAACCACCTTTAAACATGGCGATAAAAA
GCATGGTCATGTGGTGATTGTACAATTAGGCATGATGCAAATTGGTTTTGTGGTTGATGCCCTAATAGGACAAGAAGAGG
TGGTGATTAAACCCCTTGGCGCTATGTTACACGGCACTCCTGGGATGGCTGGTGCGACTATTACATCGGATGGTGGTATC
GCACTGATCTTAGATGTCCCTGGATTGTTAAAGCATTATGCGAAAAGTAAGAATTAG

Upstream 100 bases:

>100_bases
GCCGATAATGAATGCCGAGTTTCGTCAAGATGTAGTAACGGGTCAAGACGAAGTGGATGATCTTCTATCGAGTCTGGGTT
TCTAACTGGGAGTCAATTTG

Downstream 100 bases:

>100_bases
TTTCCAAGCTAAGGAATGGAATGGCCATTAAAGTATTAGTCGTTGATGACTCAAGTTTTTTCAGACGACGTGTTAGTGAA
ATAGTCAATCAAGATCCTGA

Product: signal transduction histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 738; Mature: 737

Protein sequence:

>738_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRSVNAELMDIILQAVDAINTMFAQTQQGEQQDPAESGLLSRLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVP
QDIPVEISNSSSSSIDDINDAEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
SGKFKAEAEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKGAAPAKAEVKAPTAPVTPASTAAPKAAAPAPAPV
VAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTAD
LQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREANG
KPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNLIFAPGFSTKVEISDISGRGV
GMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIV
RNKAVPLFYLEHWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGGI
ALILDVPGLLKHYAKSKN

Sequences:

>Translated_738_residues
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTG
KRSVNAELMDIILQAVDAINTMFAQTQQGEQQDPAESGLLSRLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVP
QDIPVEISNSSSSSIDDINDAEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
SGKFKAEAEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKGAAPAKAEVKAPTAPVTPASTAAPKAAAPAPAPV
VAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTAD
LQGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREANG
KPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNLIFAPGFSTKVEISDISGRGV
GMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIV
RNKAVPLFYLEHWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGGI
ALILDVPGLLKHYAKSKN
>Mature_737_residues
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSLTPMVDVCHEAENTFDLLRTGK
RSVNAELMDIILQAVDAINTMFAQTQQGEQQDPAESGLLSRLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVPQ
DIPVEISNSSSSSIDDINDAEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHGS
GKFKAEAEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKGAAPAKAEVKAPTAPVTPASTAAPKAAAPAPAPVV
AAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQIMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADL
QGAVMKTRMQPIKKVFGRFPRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREANGK
PRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNLIFAPGFSTKVEISDISGRGVG
MDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMPTLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVR
NKAVPLFYLEHWLHRNKTTFKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGGIA
LILDVPGLLKHYAKSKN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=424, Percent_Identity=40.5660377358491, Blast_Score=289, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78808; Mature: 78677

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSL
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRSVNAELMDIILQAVDAINTMFAQTQQGEQQDPAESGLL
HHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SRLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVPQDIPVEISNSSSSSIDDIND
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCH
AEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
HHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
SGKFKAEAEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKGAAPAKAEVKAPTA
CCCEEECCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PVTPASTAAPKAAAPAPAPVVAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQ
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHH
IMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
PRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREANG
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNL
CCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCEEE
IFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMP
EEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCHHHHHH
TLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEHWLHRNKTT
HHHHHHHHHHHHCCHHHHCCEEEEECCCCEEECCEEEEEEECCCCHHHHHHHHHHCCCCC
FKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGGI
CCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEECCCCE
ALILDVPGLLKHYAKSKN
EEEEECCHHHHHHHCCCC
>Mature Secondary Structure 
AFDVDEEILQDFLIEAGEILELLQEQLVALENNPDDTNLLNAIFRGFHTVKGGAGFLSL
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEH
TPMVDVCHEAENTFDLLRTGKRSVNAELMDIILQAVDAINTMFAQTQQGEQQDPAESGLL
HHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SRLKMLSSGAPLPSEVASAEVVEVVEPEPVVEAIVETPVPQDIPVEISNSSSSSIDDIND
HHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCH
AEFEALLDALHGSGKGPAAATAVASEPVVAKPAAPVKAPSASGDDITDDEFEALLDELHG
HHHHHHHHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
SGKFKAEAEVPAKPKVASAPTPQPIVDADEITDDEFERLLDELHGKGAAPAKAEVKAPTA
CCCEEECCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
PVTPASTAAPKAAAPAPAPVVAAKPKVDIAVVEKAPAKASSANVPQGETTVRVDTARLDQ
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEHHHHHH
IMNMVGELVLVRNRLVSLGISRDDEEMSKALANLDLVTADLQGAVMKTRMQPIKKVFGRF
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHH
PRVVRDLARTLNKEIDLIMVGEETDLDKNLVEALADPLVHLVRNSVDHGIEMPNEREANG
HHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KPRTGTITLSASQEGDHILLKIEDDGAGMDPEKLKKIAITRGVLDEDSASRMTDSEAYNL
CCCCEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCEEE
IFAPGFSTKVEISDISGRGVGMDVVKTRITQLNGTVHIDSMKGKGTILEIKVPLTLAIMP
EEECCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCCHHHHHH
TLMVDVAKQVFALPLSSVNEIFHLDLTKTNIVDGQLTVIVRNKAVPLFYLEHWLHRNKTT
HHHHHHHHHHHHCCHHHHCCEEEEECCCCEEECCEEEEEEECCCCHHHHHHHHHHCCCCC
FKHGDKKHGHVVIVQLGMMQIGFVVDALIGQEEVVIKPLGAMLHGTPGMAGATITSDGGI
CCCCCCCCCCEEEEEECHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCCCCCEEECCCCE
ALILDVPGLLKHYAKSKN
EEEEECCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550470; 10360571; 9989504 [H]