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The map label for this gene is yqjI [H]

Identifier: 160876079

GI number: 160876079

Start: 3525733

End: 3527259

Strand: Reverse

Name: yqjI [H]

Synonym: Sbal195_2969

Alternate gene names: 160876079

Gene position: 3527259-3525733 (Counterclockwise)

Preceding gene: 160876080

Following gene: 160876078

Centisome position: 65.96

GC content: 48.66

Gene sequence:

>1527_bases
ATGCAAAACCACAGCAATCTTAATGATATCGGCGTAATTGGCCTTGGCGTTATGGGTAAAAACCTCGCGCTAAACATCGC
GGATAACCAATATCACGTCAGCGCATTTGATCTCGATCCTGTTAAAGTTAATGGTGTTATACAGCAAGAAAAACAGGAAC
GCGCTGGACTCGAACCTCGCATTCTTGGCTGTGCTAATCTTACCGAAATGTTAGCCAGTCTCACAAAACCCCGCATTCTT
GTGCTTTCTGTTCCCGCGGGCGCACCCGTCGATGGTGTCTGTAGTGCTTTGATTTCTGCCGGAATTGAGTCAGATGATAT
CGTTATCGATACCGGTAACAGCCTATGGACCGACACTGTTGAGCGTGAAGCGCGCTACAAAGGTCAGTTTGTATTTTTCA
GCTCTGCGGTTTCGGGCGGTGAAGTCGGTGCGCGTTTCGGTCCATCACTTATGCCAAGCGGCGATATCGATGCATGGCAT
CACGTTGCACCTATTTGGAAAGCCATTGCCGCTAAGGTTGATGCAAGTACAGGTTTACCCATAGAGCGCTTCGAACCGGG
TAATCCAGTGACAGAAGGCGAGCCATGCACGACTTATATTGGTCCTGCGGGTTCTGGCCATTACGTGAAGATGGTGCACA
ACGGTATTGAATATGCTGATATGCAGTTGATTTGCGAAGCCTATCAAATGCTGCATGACGGTTTAGGCATGAGCGCTGCA
GAAGTGGGCGATGTGTTTGAACGCTGGAACAAAGGCAGCTTAAACAGCTATTTGATGGGGATCAGTGCCGAAGTCTTAAA
ACAGGCCGATCCATTAACGGGTAAACCGTTGGTGGAAATGATCTTAGATAAAGCGGGCCAAAAAGGCACGGGTTTGTGGA
CGGCCGTAAGCAGTTTACAAATTGGTTGTCCGGCACCGACGATTGCTGAAGCTGTATATGCTCGCGCCGTAAGTACCCAA
AAATCCTTACGTTTACAACTTAGCCAGAAATTGGCTGGGCCAAATGCACCTGCTATCGATGATGCGCAAAAAGCGCAGTT
GATTGAAGCCCTTGAAAGTGCTTTATATTGCGCGAAAGTGTGTTGTTACGCGCAAGGCTTCCAGTTGATGGCGATGACGG
CCCATGAACAAAAATGGCAGTTAGACTTTGCTGAAATTGCAAAAATTTGGCGTGCGGGTTGTATTATTCGCGCGACGTTC
TTGCAATCAATCACTCAAGCCTATGAAGATAATGCCGATCTTAGCAATCTGTTGATGGCCGACAGTTTTGCGTCAGCCTT
ATCTGAACAGCAAGGCCTATGGCGCACTGCGGTAGCGACAGCGGTAATGCAAGGCATTCCAGCGCCGTGTATTAGCTCAG
CACTGGCATATTACGACAGTTATCGCTGCGAAACATTACCAGCGAACTTGCTCCAAGGTCAGCGTGACTTTTTCGGCTCT
CACACCTTCGAGCGGATCGATACCCCTGCAGGCGAGAAATATCACTTAGATTGGAGCGCTAAAGAGCGCACCTTAGCTAA
GGTCTAA

Upstream 100 bases:

>100_bases
TTGCCAATCGTATGTCTCTGGTAATTAAGTTACAAAGATCGGTATAATTACCCCTCAAAATTGGTTAGCTCTAACCTCTG
TGACCCGTGGGAATTATATA

Downstream 100 bases:

>100_bases
TGTTCGTGAAAACTCGTATATAGTATTTTATAAAGACCCTCAATATTGAGGGTTTTTTTATGCTTGCACGAAATGACAAT
TAACTCATTAGCGCCAAAGA

Product: 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MQNHSNLNDIGVIGLGVMGKNLALNIADNQYHVSAFDLDPVKVNGVIQQEKQERAGLEPRILGCANLTEMLASLTKPRIL
VLSVPAGAPVDGVCSALISAGIESDDIVIDTGNSLWTDTVEREARYKGQFVFFSSAVSGGEVGARFGPSLMPSGDIDAWH
HVAPIWKAIAAKVDASTGLPIERFEPGNPVTEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQMLHDGLGMSAA
EVGDVFERWNKGSLNSYLMGISAEVLKQADPLTGKPLVEMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYARAVSTQ
KSLRLQLSQKLAGPNAPAIDDAQKAQLIEALESALYCAKVCCYAQGFQLMAMTAHEQKWQLDFAEIAKIWRAGCIIRATF
LQSITQAYEDNADLSNLLMADSFASALSEQQGLWRTAVATAVMQGIPAPCISSALAYYDSYRCETLPANLLQGQRDFFGS
HTFERIDTPAGEKYHLDWSAKERTLAKV

Sequences:

>Translated_508_residues
MQNHSNLNDIGVIGLGVMGKNLALNIADNQYHVSAFDLDPVKVNGVIQQEKQERAGLEPRILGCANLTEMLASLTKPRIL
VLSVPAGAPVDGVCSALISAGIESDDIVIDTGNSLWTDTVEREARYKGQFVFFSSAVSGGEVGARFGPSLMPSGDIDAWH
HVAPIWKAIAAKVDASTGLPIERFEPGNPVTEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQMLHDGLGMSAA
EVGDVFERWNKGSLNSYLMGISAEVLKQADPLTGKPLVEMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYARAVSTQ
KSLRLQLSQKLAGPNAPAIDDAQKAQLIEALESALYCAKVCCYAQGFQLMAMTAHEQKWQLDFAEIAKIWRAGCIIRATF
LQSITQAYEDNADLSNLLMADSFASALSEQQGLWRTAVATAVMQGIPAPCISSALAYYDSYRCETLPANLLQGQRDFFGS
HTFERIDTPAGEKYHLDWSAKERTLAKV
>Mature_508_residues
MQNHSNLNDIGVIGLGVMGKNLALNIADNQYHVSAFDLDPVKVNGVIQQEKQERAGLEPRILGCANLTEMLASLTKPRIL
VLSVPAGAPVDGVCSALISAGIESDDIVIDTGNSLWTDTVEREARYKGQFVFFSSAVSGGEVGARFGPSLMPSGDIDAWH
HVAPIWKAIAAKVDASTGLPIERFEPGNPVTEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQMLHDGLGMSAA
EVGDVFERWNKGSLNSYLMGISAEVLKQADPLTGKPLVEMILDKAGQKGTGLWTAVSSLQIGCPAPTIAEAVYARAVSTQ
KSLRLQLSQKLAGPNAPAIDDAQKAQLIEALESALYCAKVCCYAQGFQLMAMTAHEQKWQLDFAEIAKIWRAGCIIRATF
LQSITQAYEDNADLSNLLMADSFASALSEQQGLWRTAVATAVMQGIPAPCISSALAYYDSYRCETLPANLLQGQRDFFGS
HTFERIDTPAGEKYHLDWSAKERTLAKV

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=499, Percent_Identity=44.0881763527054, Blast_Score=419, Evalue=1e-117,
Organism=Escherichia coli, GI1788341, Length=491, Percent_Identity=44.806517311609, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17542558, Length=493, Percent_Identity=43.8133874239351, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321695, Length=500, Percent_Identity=45.6, Blast_Score=443, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6321977, Length=499, Percent_Identity=44.8897795591182, Blast_Score=422, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24639279, Length=493, Percent_Identity=44.2190669371197, Blast_Score=390, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 54765; Mature: 54765

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00461 6PGD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNHSNLNDIGVIGLGVMGKNLALNIADNQYHVSAFDLDPVKVNGVIQQEKQERAGLEPR
CCCCCCCCCCCEEEECEECCCEEEEEECCEEEEEEECCCCEEECCHHHHHHHHHCCCCCE
ILGCANLTEMLASLTKPRILVLSVPAGAPVDGVCSALISAGIESDDIVIDTGNSLWTDTV
EECHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
EREARYKGQFVFFSSAVSGGEVGARFGPSLMPSGDIDAWHHVAPIWKAIAAKVDASTGLP
HHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
IERFEPGNPVTEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQMLHDGLGMSAA
CCCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHH
EVGDVFERWNKGSLNSYLMGISAEVLKQADPLTGKPLVEMILDKAGQKGTGLWTAVSSLQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCC
IGCPAPTIAEAVYARAVSTQKSLRLQLSQKLAGPNAPAIDDAQKAQLIEALESALYCAKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CCYAQGFQLMAMTAHEQKWQLDFAEIAKIWRAGCIIRATFLQSITQAYEDNADLSNLLMA
HHHHCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
DSFASALSEQQGLWRTAVATAVMQGIPAPCISSALAYYDSYRCETLPANLLQGQRDFFGS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHCC
HTFERIDTPAGEKYHLDWSAKERTLAKV
CCHHHHCCCCCCEEEECCCCCCHHHHCC
>Mature Secondary Structure
MQNHSNLNDIGVIGLGVMGKNLALNIADNQYHVSAFDLDPVKVNGVIQQEKQERAGLEPR
CCCCCCCCCCCEEEECEECCCEEEEEECCEEEEEEECCCCEEECCHHHHHHHHHCCCCCE
ILGCANLTEMLASLTKPRILVLSVPAGAPVDGVCSALISAGIESDDIVIDTGNSLWTDTV
EECHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHH
EREARYKGQFVFFSSAVSGGEVGARFGPSLMPSGDIDAWHHVAPIWKAIAAKVDASTGLP
HHHHHHCCCEEEEECCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
IERFEPGNPVTEGEPCTTYIGPAGSGHYVKMVHNGIEYADMQLICEAYQMLHDGLGMSAA
CCCCCCCCCCCCCCCCEEEECCCCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHH
EVGDVFERWNKGSLNSYLMGISAEVLKQADPLTGKPLVEMILDKAGQKGTGLWTAVSSLQ
HHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCC
IGCPAPTIAEAVYARAVSTQKSLRLQLSQKLAGPNAPAIDDAQKAQLIEALESALYCAKV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
CCYAQGFQLMAMTAHEQKWQLDFAEIAKIWRAGCIIRATFLQSITQAYEDNADLSNLLMA
HHHHCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
DSFASALSEQQGLWRTAVATAVMQGIPAPCISSALAYYDSYRCETLPANLLQGQRDFFGS
HHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHCC
HTFERIDTPAGEKYHLDWSAKERTLAKV
CCHHHHCCCCCCEEEECCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]