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The map label for this gene is kdsB [H]

Identifier: 160875590

GI number: 160875590

Start: 2930662

End: 2931399

Strand: Direct

Name: kdsB [H]

Synonym: Sbal195_2478

Alternate gene names: 160875590

Gene position: 2930662-2931399 (Clockwise)

Preceding gene: 160875589

Following gene: 160875591

Centisome position: 54.81

GC content: 47.83

Gene sequence:

>738_bases
ATGAATGTGACTCTGTTAATCCCGGCTCGTTACGGTTCAAGCCGCTTCCCGGGCAAACCCTTAGCCCCGATTAACGGCAA
GCCAATGATCCAACACGTGTATGAACGCGCGTCGTTAGCCAAAGGCCTCACCAATATTTATGTCGCTACCGATGATGACC
GCATTAAAGCGGCCGTTGAAGGTTTTGGCGGCAAAGTGGTCATGACCAGCCCAGATGCAGCCTCGGGCACAGATCGTATC
AATGATGCAATAAACCAACTGGGCCTGAAAGATGACGACTTAGTGATCAACCTACAGGGTGATCAACCTCTTATTGACCC
AACCTCTATCGAGCAAGTCATCAGCCTCTTCGAGCGTCACCCAGGTGAGTTTGAAATGGCCACCTTAGGCTTTGAAATCG
TCAATAAAGCCGAGCTTGACGATCCTATGCATGTGAAGATGGTGTTCGATAACAACAACTATGCCTTGTATTTCTCTCGT
TCGCGTATTCCTTTTGGCCGCGACACCCAAGATTACCCCGTTTATAAGCACTTAGGTGTGTATGCTTATACCCGCAAATT
CGTTCAGGCCTTCGCCGCCCTACCATTAGGTCGTCTAGAAGATCTGGAAAAACTCGAGCAATTGCGCGCATTAGAGTACG
GCCATAAAATCAAAATCGCCATTAGCGCCTTTGATTCTATTGAAGTTGATACGCCAGAAGACATTCGTAAATGTGAGCAA
CGTTTAGCGGTTGATTAA

Upstream 100 bases:

>100_bases
TAAGCTCTAACACATGTTAAAAGGGCTCAATCGTGAGCCCTTTTGTCTATATGCATTGTATATCTACACTGTATATCTTT
GATAAAAGTAGGATAATTTG

Downstream 100 bases:

>100_bases
TCGCTCGTGAGTCTTGCGCGCGAGTCTATTCGAAACAGGAGCTGAGTATGTCGACCTTAGAAGTCTGGATCATTATTATT
TTGATCGTCGGTGTCATCGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSR
SRIPFGRDTQDYPVYKHLGVYAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQ
RLAVD

Sequences:

>Translated_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSR
SRIPFGRDTQDYPVYKHLGVYAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQ
RLAVD
>Mature_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVEGFGGKVVMTSPDAASGTDRI
NDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSR
SRIPFGRDTQDYPVYKHLGVYAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQ
RLAVD

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=251, Percent_Identity=43.4262948207171, Blast_Score=193, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 27434; Mature: 27434

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
GFGGKVVMTSPDAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERH
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
PGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSRSRIPFGRDTQDYPVYKHLGV
CCCEEEEEHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHH
YAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
RLAVD
HHCCC
>Mature Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHH
GFGGKVVMTSPDAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERH
CCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHC
PGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSRSRIPFGRDTQDYPVYKHLGV
CCCEEEEEHHHHHHHHHCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHH
YAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
RLAVD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA