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The map label for this gene is lolA [H]

Identifier: 160875434

GI number: 160875434

Start: 2739467

End: 2740093

Strand: Reverse

Name: lolA [H]

Synonym: Sbal195_2322

Alternate gene names: 160875434

Gene position: 2740093-2739467 (Counterclockwise)

Preceding gene: 160875435

Following gene: 160875433

Centisome position: 51.24

GC content: 43.86

Gene sequence:

>627_bases
ATGAAAAAACGATTATGCGCTGTGTTGTTAGCTTCACCTTTGCTATTTAGCGCGGCCGTGTTTGCCGATGATGCGCAGCA
GTTAAGGGACAAGTTGATTGGTACTGCTTCACTAAAAGCCGATTTCAAACAAACCGTCACTGACGTCAATAAAAAGGTCA
TTCAGACGGGTTCAGGGATTTTTGCCTTGGCCTATCCAAATCAGTTTTATTGGCATTTAACTCAGCCAGATGAATCGCAA
ATTGTCGCCGATGGTAAAGATTTATGGATTTACAATCCCTTCGCCGAAGAAGTGGTCATCATGGATTTTGCCGAGGCAAT
CAATGCTTCGCCTATTGCTTTGTTAGTCCACCGCGACGATGCTACTTGGTCACAGTATGCAGTGACCAAGCAACAAGACT
GCTATGAGATCAAACCTAAAGCGATTGATTCGGGCATATTGTCCGTCAAGGTGTGTTTCAAAAATGCCCAGTTAGCCAAC
TTTAATGTTGCCGATGACAAAGGTAACTTGAGCCAATTTGATTTGAGCAATCAGCAAGCGATTACTGATAAAGACAAAGC
GCTGTTCAGCTTTGTGCTGCCTGACAATGTCGATGTTGATGATCAACGTCGTAAAACAGCGCACTAG

Upstream 100 bases:

>100_bases
GTAACCGTGAAGTCTTAGCGCCGCCGGCACCAAAACATTATTAAGCCGCGCTAAGGCGTGGCTTTGATACACCCAAGGGT
TTTACAGGGTAAGGAATAAA

Downstream 100 bases:

>100_bases
GCAATAGCGTGAGCAGTTTATCCTTTAATTTCGCCCCCGACTTTCGTCCCTTGGCCGCACGCATGCGGCCAAGAACGATC
GCCGAGTACATAGGCCAAGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYAVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLAN
FNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH

Sequences:

>Translated_208_residues
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYAVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLAN
FNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH
>Mature_208_residues
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQ
IVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYAVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLAN
FNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=200, Percent_Identity=34, Blast_Score=124, Evalue=5e-30,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 23190; Mature: 23190

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCE
FALAYPNQFYWHLTQPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDD
EEEECCCCEEEEECCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCC
ATWSQYAVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLANFNVADDKGNLSQFDLSNQQA
CCCHHEECCCCCCCEECCCCHHCCCEEEEEEEECCCEEEECEECCCCCCCCEECCCCCCC
ITDKDKALFSFVLPDNVDVDDQRRKTAH
CCCCCCEEEEEECCCCCCCCCCHHCCCC
>Mature Secondary Structure
MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCE
FALAYPNQFYWHLTQPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDD
EEEECCCCEEEEECCCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCC
ATWSQYAVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLANFNVADDKGNLSQFDLSNQQA
CCCHHEECCCCCCCEECCCCHHCCCEEEEEEEECCCEEEECEECCCCCCCCEECCCCCCC
ITDKDKALFSFVLPDNVDVDDQRRKTAH
CCCCCCEEEEEECCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA