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The map label for this gene is aspC [H]

Identifier: 160875319

GI number: 160875319

Start: 2621789

End: 2622982

Strand: Direct

Name: aspC [H]

Synonym: Sbal195_2206

Alternate gene names: 160875319

Gene position: 2621789-2622982 (Clockwise)

Preceding gene: 160875318

Following gene: 160875321

Centisome position: 49.03

GC content: 46.57

Gene sequence:

>1194_bases
ATGATTTTCTCTCAAGTATTACTCGCACCCGCAGATCCCATTCTTGGTTTAACTGATACCTTTAAGGCTGATCCCCGTCA
GGATAAAGTTAATCTGGGTGTCGGTATTTATAAGGATGAGGCTGGACAAACTCCAGTGCTGACTTCAGTGAAAAAAGCCG
AGGCTATTTTACTTGAGCAAGAGAAGACCAAAAACTATTTAGGCATTGAAGGCGTGCAAGCGTATAACCATGTTGTACAA
ACATTGTTATTCGGTGAGGGCAGTGCATTAATCACTTCTGGCCGTGCTGCCACAGCGCAAGCCCCGGGCGGCACAGGTGC
ACTGCGTATTGCTGCTGAGTTTTTACTGCGTAATACCGATTCGCACACTATTTGGGTCAGCAATCCAACGTGGGCCAACC
ATCAAAACATTTTTGAAACTGCGGGTTTAGCCGTTAAAGAATACGGTTATTACAAAGCAGAAGCCCATGATATCGATTTT
GATACCATGATGACGGACTTGTCTCACGCGAATGCAGGCGATGTTGTGTTGCTACACGGTTGCTGCCATAACCCAACAGG
TATCGATTTAACCTTGGCGCAATGGGAACTCGTAGCCCAATTGTGTGCCGATAAGAAACTTGTGCCATTGTTTGACTTTG
CATACCAAGGTTTTGGTGCTGGAATTGAAGAAGATGCGGCTGGTCTTCGTTTAGTGGCATCAAAAGTGCCGGAGCTGCTG
GTTGCTAACTCTTTCTCTAAAAACTTTGGTTTGTACAACGAACGTATCGGCGCCGTAACTGTGGTGGCTGAAGATGCTGA
TGCTGCCGTGCGTGCCTTTAGCCAAGTGAAACGTACCATACGTGCAAACTATTCTAATCCGCCAGCACATGGCGCGCTGA
TCGTCAGCACTATCTTAAATGACGCAGCCCTGAAAGCCATGTGGGTGCAGGAAGTTAAAGAGATGCGTGAGCGTATCGCC
GAAATGCGTACCTTGTTCGTTGAAAGCTTAAAGGCTGAAGGCGTGACTCAGGACTTTAGCTTTATTTCTCGCCAAAATGG
TATGTTCAGTTTCTCTGGTTTGAATAAAGCCCAAGTGGCGCGCTTGAAAGACGAGTTTGGGGTTTATATCGTTGGTTCAG
GACGCATTAGCGTTGCAGGTATGACTAAGACCAATATGCCAGTGATCTGCAAAGCGATAGCGCAAGTATTGTAA

Upstream 100 bases:

>100_bases
TTTCCCTGAGAAGGTGCTTAAGTCGCTATTCCCCCCTTAAAGACAGTGGTATAAATAAGCCGAAATTTCCCCTACACGCG
CATAATTAGGATACGTAGTC

Downstream 100 bases:

>100_bases
GGCTTATTAGGTTATAGAAAGAGGCTAAAGGAATTTTTCTTTAGCCTTAAACATAAAGGACAGCATTTGCTGTCCTTTAT
GTTTTTCAGTATGTGCGGGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLTSVKKAEAILLEQEKTKNYLGIEGVQAYNHVVQ
TLLFGEGSALITSGRAATAQAPGGTGALRIAAEFLLRNTDSHTIWVSNPTWANHQNIFETAGLAVKEYGYYKAEAHDIDF
DTMMTDLSHANAGDVVLLHGCCHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILNDAALKAMWVQEVKEMRERIA
EMRTLFVESLKAEGVTQDFSFISRQNGMFSFSGLNKAQVARLKDEFGVYIVGSGRISVAGMTKTNMPVICKAIAQVL

Sequences:

>Translated_397_residues
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLTSVKKAEAILLEQEKTKNYLGIEGVQAYNHVVQ
TLLFGEGSALITSGRAATAQAPGGTGALRIAAEFLLRNTDSHTIWVSNPTWANHQNIFETAGLAVKEYGYYKAEAHDIDF
DTMMTDLSHANAGDVVLLHGCCHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILNDAALKAMWVQEVKEMRERIA
EMRTLFVESLKAEGVTQDFSFISRQNGMFSFSGLNKAQVARLKDEFGVYIVGSGRISVAGMTKTNMPVICKAIAQVL
>Mature_397_residues
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLTSVKKAEAILLEQEKTKNYLGIEGVQAYNHVVQ
TLLFGEGSALITSGRAATAQAPGGTGALRIAAEFLLRNTDSHTIWVSNPTWANHQNIFETAGLAVKEYGYYKAEAHDIDF
DTMMTDLSHANAGDVVLLHGCCHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILNDAALKAMWVQEVKEMRERIA
EMRTLFVESLKAEGVTQDFSFISRQNGMFSFSGLNKAQVARLKDEFGVYIVGSGRISVAGMTKTNMPVICKAIAQVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=44.1919191919192, Blast_Score=332, Evalue=5e-91,
Organism=Homo sapiens, GI4504067, Length=404, Percent_Identity=39.3564356435644, Blast_Score=295, Evalue=7e-80,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=26.6318537859008, Blast_Score=151, Evalue=1e-36,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.6262626262626, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=46.8513853904282, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=43.2911392405063, Blast_Score=350, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=43.0379746835443, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17569539, Length=399, Percent_Identity=37.0927318295739, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=30.4909560723514, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17550384, Length=267, Percent_Identity=35.5805243445693, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=39.8104265402844, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=37.192118226601, Blast_Score=274, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322743, Length=431, Percent_Identity=34.338747099768, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=41.6666666666667, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=41.6666666666667, Blast_Score=319, Evalue=3e-87,
Organism=Drosophila melanogaster, GI19922362, Length=395, Percent_Identity=41.7721518987342, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI24654046, Length=395, Percent_Identity=41.7721518987342, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI19920542, Length=391, Percent_Identity=41.4322250639386, Blast_Score=313, Evalue=1e-85,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42990; Mature: 42990

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLTSVKKAEAILLEQ
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECEEEEECCCCCCCHHHHHHHHHHHHHHH
EKTKNYLGIEGVQAYNHVVQTLLFGEGSALITSGRAATAQAPGGTGALRIAAEFLLRNTD
HHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
SHTIWVSNPTWANHQNIFETAGLAVKEYGYYKAEAHDIDFDTMMTDLSHANAGDVVLLHG
CCEEEECCCCCCCCCHHHHHHCCCHHHCCCEECCCCCCCHHHHHHHHCCCCCCCEEEEEC
CCHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
CCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHH
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILN
HHCCCHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DAALKAMWVQEVKEMRERIAEMRTLFVESLKAEGVTQDFSFISRQNGMFSFSGLNKAQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHHHH
RLKDEFGVYIVGSGRISVAGMTKTNMPVICKAIAQVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MIFSQVLLAPADPILGLTDTFKADPRQDKVNLGVGIYKDEAGQTPVLTSVKKAEAILLEQ
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECEEEEECCCCCCCHHHHHHHHHHHHHHH
EKTKNYLGIEGVQAYNHVVQTLLFGEGSALITSGRAATAQAPGGTGALRIAAEFLLRNTD
HHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCC
SHTIWVSNPTWANHQNIFETAGLAVKEYGYYKAEAHDIDFDTMMTDLSHANAGDVVLLHG
CCEEEECCCCCCCCCHHHHHHCCCHHHCCCEECCCCCCCHHHHHHHHCCCCCCCEEEEEC
CCHNPTGIDLTLAQWELVAQLCADKKLVPLFDFAYQGFGAGIEEDAAGLRLVASKVPELL
CCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHH
VANSFSKNFGLYNERIGAVTVVAEDADAAVRAFSQVKRTIRANYSNPPAHGALIVSTILN
HHCCCHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
DAALKAMWVQEVKEMRERIAEMRTLFVESLKAEGVTQDFSFISRQNGMFSFSGLNKAQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCCHHHHH
RLKDEFGVYIVGSGRISVAGMTKTNMPVICKAIAQVL
HHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]