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The map label for this gene is yfbQ [H]

Identifier: 160875299

GI number: 160875299

Start: 2598079

End: 2599293

Strand: Reverse

Name: yfbQ [H]

Synonym: Sbal195_2186

Alternate gene names: 160875299

Gene position: 2599293-2598079 (Counterclockwise)

Preceding gene: 160875302

Following gene: 160875298

Centisome position: 48.61

GC content: 47.82

Gene sequence:

>1215_bases
ATGCGCCCTATCATCAAATCCAACAAGCTGGATAGCGTTTGCTATGACATCCGCGGCCCAGTGCACAAGGAAGCCAGACG
TTTAGAAGACGAGGGTCATCGAATCCTCAAACTTAACATTGGTAATCCGGCTCCCTTCGGTTTCGAAGCGCCGGAGGAAA
TTGTGCGCGATGTGATCCTTAATCTACCCAGTGCCCAAGGCTACTGTGAGTCAAAAGGATTATTCTCTGCCCGCAAGGCC
ATAGTGCAGCATTATCAAGCCCAAGGGATTTTTGGTGTCGATATCGAAGATATCTATATAGGCAACGGCGTCTCTGAACT
CATAATGATGGCAATGCAAGGTTTGCTTAACACGGATGATGAAATTTTAATCCCCTCGCCTGACTATCCACTGTGGACGG
CGGCGGCCAATCTCGCCGGCGGCAAAGCCGTGCATTATCGTTGCGATGAAGAAGCGGACTGGTTCCCCGATCTCAACGAC
ATTAAAAGCAAAATTTCATCGCGTACCCGCGGTATTGTGCTGATCAACCCGAACAATCCTACGGGCGCGGTTTACAGCAA
AGAATTACTGCTGCAAGTGGTTGAGCTTTGCCGTGAACACAGTTTGATTTTATTTGCCGATGAAATTTACGACAAAATTT
TGTATGACGAAGCCAAGCATGTTCCTGCGGCTGGCCTGTCGGACGATATTTTAACTGTTACCTTCAATGGTCTATCAAAG
GCTTATCGCGCAGCGGGATTTCGCGTCGGTTGGATGATGTTGTCTGGCAATCTTAAAGCCGCGAAGAGCTATATCGAAGG
TTTAGAGATGCTCTCTTCGATGCGCCTGTGTGCAAACGTGCCCAATCAACATGCGATTCAAACCGCGCTCGGCGGCTATC
AAAGTATTAACGAGCTAATTTTACCTAATGGCCGTTTGACCGTTCAACGGGATGCCTGTTACGAGCTGTTGAATCAAATC
CCGGGCGTCAGCGTGAAAAAGCCTAAGGGCGCACTGTATGCTTTCCCTAAACTGGATATGAAAAAATTCAATCTGCGGGA
TGATGAGCGCTTAGTGCTGGATTTACTCAGAGAAAAGAAAATTCTGTTAGTGCACGGCACCGCCTTTAATTGGCCTGAGC
CCGACCATTTACGAGTGGTTTTCTTACCCTATAAAGAAGATCTGAAAAAAGCATTTACCGAGTTTGGCGCCTTCCTCGAA
AACTATCGGCAGTAG

Upstream 100 bases:

>100_bases
AAAAGTCCCATTCTGTGCTGCTCCCCCCTTTCATCTACAGTGAAATTTCGTTATGGTGCGCTAACTTAAGCCAAAACTTT
ATGCATGTTCCGAGGTGTAA

Downstream 100 bases:

>100_bases
GTTTAGCCTCGACTAACAGTTTGAGTCATAAAGCGATCCTAGTGGTCGCTTTATTTTTAGCGATTTCGACAAATCCTCCA
CGCTCATACTCACGTGTCAC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQAQGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLND
IKSKISSRTRGIVLINPNNPTGAVYSKELLLQVVELCREHSLILFADEIYDKILYDEAKHVPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGTAFNWPEPDHLRVVFLPYKEDLKKAFTEFGAFLE
NYRQ

Sequences:

>Translated_404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQAQGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLND
IKSKISSRTRGIVLINPNNPTGAVYSKELLLQVVELCREHSLILFADEIYDKILYDEAKHVPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGTAFNWPEPDHLRVVFLPYKEDLKKAFTEFGAFLE
NYRQ
>Mature_404_residues
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQAQGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLND
IKSKISSRTRGIVLINPNNPTGAVYSKELLLQVVELCREHSLILFADEIYDKILYDEAKHVPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQI
PGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGTAFNWPEPDHLRVVFLPYKEDLKKAFTEFGAFLE
NYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=27.1276595744681, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=25.1111111111111, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI19263340, Length=473, Percent_Identity=25.5813953488372, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI215599424, Length=382, Percent_Identity=26.4397905759162, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=268, Percent_Identity=26.4925373134328, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI169881279, Length=268, Percent_Identity=26.4925373134328, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI56713256, Length=302, Percent_Identity=24.8344370860927, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713254, Length=302, Percent_Identity=24.8344370860927, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169881281, Length=147, Percent_Identity=29.9319727891156, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI149944424, Length=388, Percent_Identity=21.6494845360825, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=69.059405940594, Blast_Score=606, Evalue=1e-175,
Organism=Escherichia coli, GI1788722, Length=407, Percent_Identity=25.3071253071253, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786816, Length=300, Percent_Identity=23.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787909, Length=297, Percent_Identity=20.8754208754209, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=27.5862068965517, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=470, Percent_Identity=24.0425531914894, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=204, Percent_Identity=26.9607843137255, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=204, Percent_Identity=26.9607843137255, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=174, Percent_Identity=28.1609195402299, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=24.2320819112628, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=473, Percent_Identity=25.369978858351, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=380, Percent_Identity=27.6315789473684, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=24.4725738396624, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=24.0740740740741, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI45551451, Length=469, Percent_Identity=23.8805970149254, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24641770, Length=459, Percent_Identity=23.9651416122004, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24641760, Length=459, Percent_Identity=23.9651416122004, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24641768, Length=459, Percent_Identity=23.9651416122004, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24641766, Length=459, Percent_Identity=23.9651416122004, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24641764, Length=459, Percent_Identity=23.9651416122004, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI28573069, Length=168, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24646114, Length=168, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573067, Length=168, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573065, Length=168, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45367; Mature: 45367

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQAQGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCHHHHHHHHHHHHCCCCC
EILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLNDIKSKISSRTRGIVLINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCC
TGAVYSKELLLQVVELCREHSLILFADEIYDKILYDEAKHVPAAGLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHC
LPNGRLTVQRDACYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKK
CCCCCEEEEHHHHHHHHHHCCCCEEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHHCCC
ILLVHGTAFNWPEPDHLRVVFLPYKEDLKKAFTEFGAFLENYRQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQAQGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCHHHHHHHHHHHHCCCCC
EILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLNDIKSKISSRTRGIVLINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCEEEEECCCCC
TGAVYSKELLLQVVELCREHSLILFADEIYDKILYDEAKHVPAAGLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHC
LPNGRLTVQRDACYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKK
CCCCCEEEEHHHHHHHHHHCCCCEEECCCCCEEECCCCCCHHCCCCCHHHHHHHHHHCCC
ILLVHGTAFNWPEPDHLRVVFLPYKEDLKKAFTEFGAFLENYRQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]