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The map label for this gene is asnC [H]

Identifier: 160875062

GI number: 160875062

Start: 2327033

End: 2328433

Strand: Reverse

Name: asnC [H]

Synonym: Sbal195_1947

Alternate gene names: 160875062

Gene position: 2328433-2327033 (Counterclockwise)

Preceding gene: 160875064

Following gene: 160875051

Centisome position: 43.54

GC content: 48.75

Gene sequence:

>1401_bases
ATGAGCATCGCATCTGTCGCATCTGTATTTAAAGGTGAGCACGCCGTCGGTTCTAAAGTCACAGTTCGTGGCTGGGTCAG
AACCCGTCGTGACTCTAAAGCCGGCATCTCTTTTTTAGCTGTTTATGACGGCTCTTGCTTTAATCCTATCCAAGGTGTCG
TGCCCAATAGCTTAGATAATTACGACAACGAAGTGTTAAAGCTGACTGCGGGTTGTTCTGTTGTGATGACAGGCGACGTG
GTGGAATCTCCAGGCGCAGGTCAAGCATTTGAGCTGCAAGTGACTGAACTTGAAGTCGCGGGCTGGGTTGATGATCCAGA
CACTTACCCAATGGCCGCTAAGCGTCACTCGATTGAACATTTACGCGAATTAGCTCACTTACGCCCACGCACTAACATTA
TTGGTGCCGTTGCCCGCGTGCGTAACTGTTTATCCCAAGCGATTCACCGCTTCTACCACGAAGAAGGCTTTATTTGGGTA
TCGACCCCACTTATCACCGCCTCTGACTGTGAAGGTGCCGGTGAAATGTTCCGCGTATCGACCTTAGATATGGAAAACCT
GCCACGTACTGATGCAGGAAAAGTCGATTACGATAAAGATTTCTTCGGTAAAGAAGCTTTCCTAACCGTATCTGGCCAGT
TGAACGCTGAAACCTACGCCTGTGCACTGTCAAAAGTGTATACCTTTGGCCCGACTTTCCGTGCTGAAAACTCAAACACT
AGCCGCCACTTAGCGGAATTCTGGATGGTTGAGCCTGAAGTGGCCTTCGCTAACTTAAACGACATCGCTGGCCTTGCCGA
AGCTATGTTGAAATACGCATTCAATGCCGTATTGACTGAGCGTATGGACGATTTAACCTTCTTCGCCCAGCACGTTGATA
AGACAGTGATCGACCGTCTGCAATCTTTCGTTTCAAGCGATTTTGCACAAGTGGATTACACAGATGCGGTTGAAATTCTG
CAAAACTGTGGCAGAACCTTCGAGTTCCCAGTGTCTTGGGGTATCGACTTATCTTCTGAGCACGAGCGTTACTTAGCCGA
AGAACACTTCAAAGCCCCTGTGGTAGTGAAGAACTATCCGAAAGATATCAAAGCCTTCTACATGCGCTTAAACGATGACG
GTAAAACAGTTGCCGCGATGGACGTGTTAGCCCCAGGTATCGGTGAAATCATCGGTGGGTCTCAACGTGAAGAGCGTTTA
GACGTGCTGGATATGCGTTTAGCCGAAATGGATCTGAACCAAGAAGATTACTGGTGGTACCGTGATATGCGCCGTTATGG
CACAGTGCCACACGCAGGTTTTGGTCTAGGGTTTGAGCGTTTAGTGTCTTACGTGACGGGCGTTAACAACATTCGTGATG
TTATCCCGTTCCCACGTGCACCGCGCACTGCGAACTTCTAA

Upstream 100 bases:

>100_bases
GCCTCAGGATACCTTTTTCAGCTTGAGAAAAGCCACCAGCAAGGTAATATAAACCTCCAAAATTTTCATATAAAACGTTT
CGTTGGAGAATTAAGCAACA

Downstream 100 bases:

>100_bases
TATCCTTTTGATTGGGCTTGTGACTCTTTGGGGAGTAACAAGCTCAACATTAGAATATAACCTAAGGCGTCGCTATTGAG
CCTTAGCAAAACAAAAAAAG

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDNYDNEVLKLTAGCSVVMTGDV
VESPGAGQAFELQVTELEVAGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWV
STPLITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRLQSFVSSDFAQVDYTDAVEIL
QNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLAEMDLNQEDYWWYRDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF

Sequences:

>Translated_466_residues
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDNYDNEVLKLTAGCSVVMTGDV
VESPGAGQAFELQVTELEVAGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWV
STPLITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRLQSFVSSDFAQVDYTDAVEIL
QNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDMRLAEMDLNQEDYWWYRDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF
>Mature_465_residues
SIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDNYDNEVLKLTAGCSVVMTGDVV
ESPGAGQAFELQVTELEVAGWVDDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVS
TPLITASDCEGAGEMFRVSTLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRLQSFVSSDFAQVDYTDAVEILQ
NCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLD
VLDMRLAEMDLNQEDYWWYRDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=42.0258620689655, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI4758762, Length=463, Percent_Identity=28.0777537796976, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI45439306, Length=355, Percent_Identity=27.3239436619718, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=80.4721030042919, Blast_Score=810, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=33.9449541284404, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=429, Percent_Identity=31.2354312354312, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=29.646017699115, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17551876, Length=340, Percent_Identity=26.7647058823529, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=489, Percent_Identity=35.9918200408998, Blast_Score=293, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6321807, Length=464, Percent_Identity=30.1724137931034, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6323011, Length=349, Percent_Identity=26.647564469914, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=34.9137931034483, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI19921528, Length=479, Percent_Identity=28.1837160751566, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=27.4052478134111, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52165; Mature: 52034

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDN
CCHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCCCCC
YDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTELEVAGWVDDPDTYPMAAKRHSIEH
CCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRL
HHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVEILQNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCHHHHHHHHHHCCCCEECCCEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNQEDYWWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SIASVASVFKGEHAVGSKVTVRGWVRTRRDSKAGISFLAVYDGSCFNPIQGVVPNSLDN
CHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCCEEEEEEECCCCCCCHHCCCCCCCCC
YDNEVLKLTAGCSVVMTGDVVESPGAGQAFELQVTELEVAGWVDDPDTYPMAAKRHSIEH
CCCCEEEEECCCEEEEECCEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYHEEGFIWVSTPLITASDCEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCCCCCEEEEE
TLDMENLPRTDAGKVDYDKDFFGKEAFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLNDIAGLAEAMLKYAFNAVLTERMDDLTFFAQHVDKTVIDRL
HHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSFVSSDFAQVDYTDAVEILQNCGRTFEFPVSWGIDLSSEHERYLAEEHFKAPVVVKNYP
HHHHHCCCCCCCHHHHHHHHHHCCCCEECCCEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDMRLAEMDLNQEDYWWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHH
RDMRRYGTVPHAGFGLGFERLVSYVTGVNNIRDVIPFPRAPRTANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA