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The map label for this gene is hypE [H]

Identifier: 160875027

GI number: 160875027

Start: 2280844

End: 2281860

Strand: Reverse

Name: hypE [H]

Synonym: Sbal195_1912

Alternate gene names: 160875027

Gene position: 2281860-2280844 (Counterclockwise)

Preceding gene: 160875028

Following gene: 160875026

Centisome position: 42.67

GC content: 50.84

Gene sequence:

>1017_bases
ATGGCTGATACGCTAAAAGATAAATCCATTCAACTCAGCCACGGCGGTGGCGGCAAAGAAATGAATAAACTGATCCGTGA
TCTGTTTTTTGCCGAATTTGATAACCCAATCCTTCGTAGCGAAGAAGACGCTGCCAAACTCGATTTGCACGGCGCCAACG
CCTTTACTACTGACTCTTTTACCGTCTCACCTTTGTTTTTTGCCGGCGGCGATATCGGCAAACTTGCTATCGCGGGCACA
GTCAACGATCTCGCTATGATGGGTGCAGAACCTCAGTATCTGAGCTGTAGCGTGATCATCGAAGAAGGCTTTTCTATCAA
TGATTTAACGACTATTGTCCGCAGCATGGCAAAAGAGCTCAAACAAAGTGGCGCGCGGATTGTCTGCGGCGACACTAAAG
TCGTGCCCAAGGGCTGTGCCGATGGTTTATTTATTAATACCTCAGGCATTGGCCGCATCTTGCGTCCCAACATCTCAGCG
GCAAACATTGCAGTGGGCGATGCCATTATCGTCTCCCGTGATATTGGCTGCCACGGCGCGGCGATTTTAATGGCGCGTGA
AGGACTCACGCTCGAATCGGCATTGCAAAGTGACTGCGCGACGCTCTGGCCCATAGTCGAGCAATTGATCGCCGCCAATA
TTCCTATCCATGCGATGCGCGATGCGACTCGCGGTGGCTTATCGGCAGTGCTCAATGAATGGGCTGTCGCCTCCAATGTT
GGCATTACAGTCAATGAGGCCAGTATTCCCGTCAGCGATGAAGTCAAAGGTCTGTGTGAACTCTATGGTTTCGAAGCCAT
GGATCTCGCTAACGAAGGCACTTTCATTCTCGCCGTCCCCAATGACATAGCATTAGGCGCGCTCGAGATCATGCAACGCT
TTGGGCGCTGTGAGCATGCAGCGATAATCGGCACTGTGAGTGAAGATTTAGTGGGGAAAGTCGTACTAAGAACGCCTTGG
AATACTAAGCGTTATCTCGATCTTCCCCAAGGTGAACTGCTGCCAAGGATTTGCTGA

Upstream 100 bases:

>100_bases
TGCAATCCCGAAACGCCCTTAGGCAGCTGCATGGTCAGCTCCGAAGGTGCATGTAACGCCTATTACCGCTATCAAGGTAT
CGATATCAAGGAGCCACATC

Downstream 100 bases:

>100_bases
TGCACGAATATTCGATTGTGAGTGCCCTGATTGAGCAATGTGAACAGCACGCGCAGGCCAATCATGCCGATAAAATCACC
CGAGTGGATATCAAACTGGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MADTLKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGT
VNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISA
ANIAVGDAIIVSRDIGCHGAAILMAREGLTLESALQSDCATLWPIVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
GITVNEASIPVSDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGRCEHAAIIGTVSEDLVGKVVLRTPW
NTKRYLDLPQGELLPRIC

Sequences:

>Translated_338_residues
MADTLKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGT
VNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISA
ANIAVGDAIIVSRDIGCHGAAILMAREGLTLESALQSDCATLWPIVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
GITVNEASIPVSDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGRCEHAAIIGTVSEDLVGKVVLRTPW
NTKRYLDLPQGELLPRIC
>Mature_337_residues
ADTLKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGTV
NDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAA
NIAVGDAIIVSRDIGCHGAAILMAREGLTLESALQSDCATLWPIVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNVG
ITVNEASIPVSDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGRCEHAAIIGTVSEDLVGKVVLRTPWN
TKRYLDLPQGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=340, Percent_Identity=47.3529411764706, Blast_Score=280, Evalue=9e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35973; Mature: 35842

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTLKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSF
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEECCCCCEECCCE
TVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKEL
EECEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
KQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAANIAVGDAIIVSRDIGCHGA
HHCCCEEEECCCEECCCCCCCCEEEECCCCCCEECCCCCCCEEEECCEEEEEECCCCCCE
AILMAREGLTLESALQSDCATLWPIVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCC
GITVNEASIPVSDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGRCEHA
CEEEECCCCCCCHHHHHHHHHHCCHHEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCE
AIIGTVSEDLVGKVVLRTPWNTKRYLDLPQGELLPRIC
EEEEECCHHHHCEEEEECCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure 
ADTLKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSF
CCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEECCCCCEECCCE
TVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKEL
EECEEEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHH
KQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAANIAVGDAIIVSRDIGCHGA
HHCCCEEEECCCEECCCCCCCCEEEECCCCCCEECCCCCCCEEEECCEEEEEECCCCCCE
AILMAREGLTLESALQSDCATLWPIVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNV
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHHHHHCCC
GITVNEASIPVSDEVKGLCELYGFEAMDLANEGTFILAVPNDIALGALEIMQRFGRCEHA
CEEEECCCCCCCHHHHHHHHHHCCHHEEECCCCEEEEECCCCHHHHHHHHHHHHCCCCCE
AIIGTVSEDLVGKVVLRTPWNTKRYLDLPQGELLPRIC
EEEEECCHHHHCEEEEECCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]