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The map label for this gene is hlyB [H]

Identifier: 160875021

GI number: 160875021

Start: 2273618

End: 2275138

Strand: Reverse

Name: hlyB [H]

Synonym: Sbal195_1906

Alternate gene names: 160875021

Gene position: 2275138-2273618 (Counterclockwise)

Preceding gene: 160875026

Following gene: 160875017

Centisome position: 42.55

GC content: 48.39

Gene sequence:

>1521_bases
ATGAAAGAAGTAAAGTTTCGCTGGATAGATCAATATCTTATCCATATGACCTTAAAAACTAAATTCGCTATTCTCTCTAT
CGTTCCCATGCTAATGATTGTTGGACTGGCGATTTTTCTTGATAACCAATCCCAGCAAACCTTAGTGCAAGGACAGCTCA
ACGGTCTACAAAATGCGTCACAACAAATAAACCAAGTCACGGGCACCTTATATAACAAACTACCAGAGCAAGAACGCCAA
ACGATCCTTAGCCAGCTAAGTCGCGAAATCAAAGGCAATGTCAGCATTATTTCCGTGAATGAAGCCGACAGCAAAGCGCA
ATCCTTAGCCCGCAGCGGTGGCGGCATTGATGATAGCGGTAAGCAACCTCGAGCTGTGAGTCGCGTTAACGATCAAAACC
TGATCACGATTATTCCCTTAGACAGCACAGAAATTGATGCCTTGCTCGCCAAAGATAACCTGCTGGTTTACGGCCTGATG
GCGGCGCTTCTGTTCGTGTTGTTTTTATTTAGTTACTACATTTCGACCTTCGTGGGCGGCGCACTTTATACCACAGTGAT
GGCATTAAAACGCGCCGCATCGGGTGACTTAACCGGACGTTTAAACTTCTTCGAGGTAAAGGACGAATTCAGTATCTTAG
CCATCAGCATTGATGCCTTAGTGGAGCGTCAGCATCTGTTAGTGAAACAAATCGCTGAATCGACGACGAAAATCCGCGAG
GTAGTGTCCTCGTTTCGTAGCACAGCGCAACAAGGTCAATCCTTGGCGGTGAACCAGAGACAACATTTGGACTCCCTAGC
GACGGCGATGGAAGAAATGACCGCCGCAGTGAAGGAAGTCGCCCGCAATGCCGAGCAATCTTCTGCCGAAACTCAAGAGG
CTAATCAACAAGTTAGCGCGGGCGGTAAAGACATTGAAACCACAGTCAAAGCTATTGACGTGTTATCGGATGAGATCTCC
TCAGCCTCGAATGCGGTGGGCGTACTCAATGACAACGCCAGTAAAATTGATGAAGTGGTATCAACTATTAATGCGATTTC
CCAGCAAACCAACCTACTCGCCCTCAACGCGGCGATTGAAGCGGCGCGCGCTGGTGAACAAGGTCGTGGTTTTGCCGTGG
TCGCCGATGAAGTGCGTACCTTAGCGGGCCGCACTCAAGCCGCGACGGTTGAGATCAAAACCATGATCGAATCGCTGCAA
TCGGGCACTCGCAATCTAACCCAAGTGATGTCACGTACTGTGAGTCAAGCGAATGAAGGCAAACAACACGTACTGCAAAC
GGGTAAAGACTTAGAGTTTATCGCCCATCACAGTAATAAAGTGTTTGAAATGAGTGTGCTAATCGCCACCTCGGCCGAAG
AACAATCGGCTGTGGCCAACGAGATTGCGACTAACCTGATGGAAATCCGCAACCAGTCCCACGATGTGGAGCAATCGGCT
AACCAGTCGGTTTCAGGTTGTGATGAGCTGCAAGCAACAGCTGGGCAGCTTGATCAGTTGATGGTGGGATTAAAAATCTA
G

Upstream 100 bases:

>100_bases
TACATTAGCGATATAAATCATTACAAAACAGAAAACTATCAAGTCTATGGCAAACTGACCGATATACATTCGGTTCACAG
CCCATTTTATCGAGGCACTC

Downstream 100 bases:

>100_bases
TCGAGCATTATTTGATGGAATTTAAATTCACTTAACACCCAAAATGCACCAGGGAGCGATAATCGCTCCCTTGTTGTTTT
TTCATTCTGACGGTAACGGT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNASQQINQVTGTLYNKLPEQERQ
TILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDDSGKQPRAVSRVNDQNLITIIPLDSTEIDALLAKDNLLVYGLM
AALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDVLSDEIS
SASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQ
SGTRNLTQVMSRTVSQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
NQSVSGCDELQATAGQLDQLMVGLKI

Sequences:

>Translated_506_residues
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNASQQINQVTGTLYNKLPEQERQ
TILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDDSGKQPRAVSRVNDQNLITIIPLDSTEIDALLAKDNLLVYGLM
AALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDVLSDEIS
SASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQ
SGTRNLTQVMSRTVSQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
NQSVSGCDELQATAGQLDQLMVGLKI
>Mature_506_residues
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNASQQINQVTGTLYNKLPEQERQ
TILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDDSGKQPRAVSRVNDQNLITIIPLDSTEIDALLAKDNLLVYGLM
AALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDVLSDEIS
SASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQ
SGTRNLTQVMSRTVSQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
NQSVSGCDELQATAGQLDQLMVGLKI

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=320, Percent_Identity=31.25, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI2367378, Length=306, Percent_Identity=31.0457516339869, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787690, Length=194, Percent_Identity=38.659793814433, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788194, Length=150, Percent_Identity=44.6666666666667, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=187, Percent_Identity=33.1550802139037, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54844; Mature: 54844

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQINQVTGTLYNKLPEQERQTILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDDSG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCC
KQPRAVSRVNDQNLITIIPLDSTEIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGG
CCCCHHHHCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKDIETTVKAIDVLSDEISSASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIE
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEHHHHHH
AARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQSGTRNLTQVMSRTVSQANEG
HHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
KQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
HHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NQSVSGCDELQATAGQLDQLMVGLKI
CCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILSIVPMLMIVGLAIFLDNQSQQTLVQGQLNGLQNAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQINQVTGTLYNKLPEQERQTILSQLSREIKGNVSIISVNEADSKAQSLARSGGGIDDSG
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCC
KQPRAVSRVNDQNLITIIPLDSTEIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGG
CCCCHHHHCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDALVERQHLLVKQIAESTTKIRE
HHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
VVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGKDIETTVKAIDVLSDEISSASNAVGVLNDNASKIDEVVSTINAISQQTNLLALNAAIE
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEHHHHHH
AARAGEQGRGFAVVADEVRTLAGRTQAATVEIKTMIESLQSGTRNLTQVMSRTVSQANEG
HHHCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
KQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSA
HHHHHHCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHH
NQSVSGCDELQATAGQLDQLMVGLKI
CCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]