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The map label for this gene is ligA [H]

Identifier: 160875001

GI number: 160875001

Start: 2254735

End: 2255682

Strand: Direct

Name: ligA [H]

Synonym: Sbal195_1886

Alternate gene names: 160875001

Gene position: 2254735-2255682 (Clockwise)

Preceding gene: 160874999

Following gene: 160875003

Centisome position: 42.17

GC content: 46.31

Gene sequence:

>948_bases
ATGACTCATACCAGCCCGTTACAAGATTTAACATTTCATCGGTTTATCCGCTTTCGTTTTTTCAAACAACGCCTGCTCTT
ACTCAGTCTGCTGATATTAGGTTGTTTAGCCCCAGTGACCTATGCGCAAAACTCTCCACCTTCGATACAGTTGGCAACTG
AGTTTGATGCCCAGCAAGAGATTCATATTCAGGACTTTTTGGTTAGCGAAAAACTCGACGGGGTGCGAGGTTACTGGAAT
GGTCAGGCACTATTGACCCGGCAAGGTAATCTTATTGCTGCTCCGACATGGTTTATCGCGAATTTCCCGAATTATCCCCT
CGATGGTGAGTTATGGCTTGGGCGAGGCCAGTTTGAGGCTATGTCGAGCATAGTTCGACAAACCTCAGCCAAGGATGATG
ACTGGCGCAAAGTGCGATTTATGGTGTTCGATGTTCCCAAGGCGGGTGGCGACTTTCAGCATCGCTATCAATTTGCGTTA
ACTAAACTGAGTGGCAAATCGCATTATCTTGAAGTCATAGCGCAGTTCCAAGTGGACAGTCTTGAAGCTCTGTATCAAAA
ACTTGATAGCTTAGTTGCTAAAGGCGCTGAAGGATTAATGCTGCATCGCAGCTCCGCGATGTATGTCAGTGGCCGCAATC
CTAATTTGATGAAATTAAAACCCTATTATGATGCTGAAGCGACAGTGATCGGCCATATACCAGGCAAAGGTCAATTTGCA
GGGCAAATGGGTGCAATAAGAGTGCAAACTCCAGACGGCCGGATTTTCAACATAGGCACAGGTTTTAATCTCGCAGAGCG
TCAGCATCCCCCCGCTGTGGGGGCAATCATCACCTATAAATATCTGGGTCTTACCGTAAATGGCTTACCCAGATTTGCCA
GCTTTCTGCGGGTACGCATCGATTTAGATGAGAGTAATAAAGTCATTTCATCGCAAGAAGGAAACTAG

Upstream 100 bases:

>100_bases
GTTAACTTAGGCGCTTAGTGACTTGCGACGGTTTTTTAGTGCAACTTGAGCTATGCGTTCTAAGCTTGATGAAGGATATA
TTGCCAGAGTGAGCAAGGGA

Downstream 100 bases:

>100_bases
CGGGCAGTTCTGCCCGCAATACTGCTCCGCTAGTATTTAAATTATTACTCGTAAAAAGTGACTGTAGTAAGTAGTTGTTC
ACTATAACTAAAAATATCGT

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTHTSPLQDLTFHRFIRFRFFKQRLLLLSLLILGCLAPVTYAQNSPPSIQLATEFDAQQEIHIQDFLVSEKLDGVRGYWN
GQALLTRQGNLIAAPTWFIANFPNYPLDGELWLGRGQFEAMSSIVRQTSAKDDDWRKVRFMVFDVPKAGGDFQHRYQFAL
TKLSGKSHYLEVIAQFQVDSLEALYQKLDSLVAKGAEGLMLHRSSAMYVSGRNPNLMKLKPYYDAEATVIGHIPGKGQFA
GQMGAIRVQTPDGRIFNIGTGFNLAERQHPPAVGAIITYKYLGLTVNGLPRFASFLRVRIDLDESNKVISSQEGN

Sequences:

>Translated_315_residues
MTHTSPLQDLTFHRFIRFRFFKQRLLLLSLLILGCLAPVTYAQNSPPSIQLATEFDAQQEIHIQDFLVSEKLDGVRGYWN
GQALLTRQGNLIAAPTWFIANFPNYPLDGELWLGRGQFEAMSSIVRQTSAKDDDWRKVRFMVFDVPKAGGDFQHRYQFAL
TKLSGKSHYLEVIAQFQVDSLEALYQKLDSLVAKGAEGLMLHRSSAMYVSGRNPNLMKLKPYYDAEATVIGHIPGKGQFA
GQMGAIRVQTPDGRIFNIGTGFNLAERQHPPAVGAIITYKYLGLTVNGLPRFASFLRVRIDLDESNKVISSQEGN
>Mature_314_residues
THTSPLQDLTFHRFIRFRFFKQRLLLLSLLILGCLAPVTYAQNSPPSIQLATEFDAQQEIHIQDFLVSEKLDGVRGYWNG
QALLTRQGNLIAAPTWFIANFPNYPLDGELWLGRGQFEAMSSIVRQTSAKDDDWRKVRFMVFDVPKAGGDFQHRYQFALT
KLSGKSHYLEVIAQFQVDSLEALYQKLDSLVAKGAEGLMLHRSSAMYVSGRNPNLMKLKPYYDAEATVIGHIPGKGQFAG
QMGAIRVQTPDGRIFNIGTGFNLAERQHPPAVGAIITYKYLGLTVNGLPRFASFLRVRIDLDESNKVISSQEGN

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 35416; Mature: 35285

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTSPLQDLTFHRFIRFRFFKQRLLLLSLLILGCLAPVTYAQNSPPSIQLATEFDAQQE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
IHIQDFLVSEKLDGVRGYWNGQALLTRQGNLIAAPTWFIANFPNYPLDGELWLGRGQFEA
CHHHHHHHHHHCCCCCCEECCCEEEEECCCEEECCEEEEECCCCCCCCCCEEECCCHHHH
MSSIVRQTSAKDDDWRKVRFMVFDVPKAGGDFQHRYQFALTKLSGKSHYLEVIAQFQVDS
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHCHHH
LEALYQKLDSLVAKGAEGLMLHRSSAMYVSGRNPNLMKLKPYYDAEATVIGHIPGKGQFA
HHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCC
GQMGAIRVQTPDGRIFNIGTGFNLAERQHPPAVGAIITYKYLGLTVNGLPRFASFLRVRI
CCCCEEEEECCCCCEEEECCCCCCHHHCCCCCHHHEEEEEEEEEEECCHHHHHHEEEEEE
DLDESNKVISSQEGN
EECCCCCCCCCCCCC
>Mature Secondary Structure 
THTSPLQDLTFHRFIRFRFFKQRLLLLSLLILGCLAPVTYAQNSPPSIQLATEFDAQQE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
IHIQDFLVSEKLDGVRGYWNGQALLTRQGNLIAAPTWFIANFPNYPLDGELWLGRGQFEA
CHHHHHHHHHHCCCCCCEECCCEEEEECCCEEECCEEEEECCCCCCCCCCEEECCCHHHH
MSSIVRQTSAKDDDWRKVRFMVFDVPKAGGDFQHRYQFALTKLSGKSHYLEVIAQFQVDS
HHHHHHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHEEEEEECCCCHHHHHHHHHHCHHH
LEALYQKLDSLVAKGAEGLMLHRSSAMYVSGRNPNLMKLKPYYDAEATVIGHIPGKGQFA
HHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCCEEEECCCCCCCEEEEEECCCCCCCC
GQMGAIRVQTPDGRIFNIGTGFNLAERQHPPAVGAIITYKYLGLTVNGLPRFASFLRVRI
CCCCEEEEECCCCCEEEECCCCCCHHHCCCCCHHHEEEEEEEEEEECCHHHHHHEEEEEE
DLDESNKVISSQEGN
EECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]