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The map label for this gene is ppx [H]

Identifier: 160874984

GI number: 160874984

Start: 2232196

End: 2233758

Strand: Reverse

Name: ppx [H]

Synonym: Sbal195_1869

Alternate gene names: 160874984

Gene position: 2233758-2232196 (Counterclockwise)

Preceding gene: 160874985

Following gene: 160874983

Centisome position: 41.77

GC content: 49.2

Gene sequence:

>1563_bases
TTGGTAGCCACACATTCGCACACACAGCAACACACATTACTAAAGTCGCAGGCGCCACAAACCAATGCGCCTGCAAATGC
TAAATCGCGCCATTTTGTCGCCATCGATATGGGGTCGAACAGTTTTCATCTGGTCATCGCCCGCGAGCAAGATGGCAGTT
TGCAGATTTTACATAAAGAAAAACAACAGGTTCAGCTCGCCACTGGGCTCAATGCGCAGAATATTCTCGATAATGACGCC
ATAGAACGTGGTCTCAATTGTCTGCGGGATTTTAACCAAAGATTTTCCAATCTAGACCAAGCGCAAGTGCGATTAGTGGC
CACCCACACCCTCAGAATCGCCAAAAACCGCGATCAATTTATCGAGGCCGCGCTCGCCATCATGCCCTATCCGGTGGAAG
TGATTTCGGGCCATGAAGAAGCCCGTTTGATTTATAACGGCATTGCCCAAAGCCAAGTGCTTGGAAAAAGTAATTTAGTC
ATCGACATTGGTGGTGGCTCGACCGAAGTTGTGATCGGTAAAAAGAATACCCCAACCCAGTTATCTAGCCTGCGCTGCGG
TTGCGTGAGTTTTAACGAGCGTTTCTTTATCGATGGACTCATCACCCCAGCCTCATTTCGTGATGCCCAAAGCGCGGCCG
ACAAACAGTTCGCCTCGCTCTCCAAGGAATATTTCGCGGGCGGCTGGGAGCTAACGTTAGGCAGCTCAGGCACAGTCAAA
GCCATCTGCGAAGCGATTCAAGAAGAACACGGCGATGAAACCATCACGCTGCCACGACTCAAACAGCTCAAAATCAAGTT
GATCAAATGTGGCCATATTAGCCAAATTCAATTTGCCAATGTCGATGATAAACGCATTCCCTTAGTGCCCGCCGGACTTG
CGATTTTAATCAGCTTTTTTAGGCGCTTACCGATACAAAAGCTCGAGTTTAGCCCAGGCGCATTGCGTGAAGGCGTTCTC
TATGAACTGGCCAAAATTGGCCAGTATCAGGATATTCGCCACCGCACCGTCGACAGTATTGCCCAGCTTTATCATATCGA
TATGGCCCACGCCGCTAAGGTACGCGACACTGCCATGGCCTTGTTTGAACAGGTCGCCGATGAATGGCAATTAAGGCCCC
ATGCACGCTTGCTTGCCTATGGCGCAACCTTACATGAGATAGGGCTACACATTAATTCAAAGTCCCTGCACAAACACGGT
GGCTATATCATCAGCAACAGTGACTTACCCGGGTTTAGCGAAGCCTTGCAGCTTGATTTAGCGCGGCTTATCACCAACCA
CAGAAAAAAGCCCAACGAATTAATGCTCGCCGAACTTGAGCCCAACCATAAGCTCACGTTGAATCGCCTGCTCTGCCTGC
TGAGGCTCGCTGTCTTACTCAACCTTGGCCGTATCGCTAAGACGCTGACCTTAGATCATATTAAAGTGATCCCCGATGGG
CTCATGTTAGTGCTACCAAGCCATAAGCGAAAAATCAGCCTGTTTATGAAGGATTTACAGCGGGAACAGAAACAAATGCT
CACCCTTGGGATGAACCTGCGATTAGTGTCTAGTTTGACTTAG

Upstream 100 bases:

>100_bases
AGCGAGAGATTAACGCTGAGCCTGACATAACGCCCGAGTTACAGGCCAAAGCCAGCTAACGCTGGCTTTATATCGCTTTG
ATTGCCTAAGGATAATCCGA

Downstream 100 bases:

>100_bases
CTGTTACGGCGTTAACTCTGCCGAACGTGGCTGAGGCGAGTGTGAGTTAGCTCTGTGTGAATGCGTTTAGCGAAGGATTC
GGCACAAAAATATTGCCCAG

Product: Ppx/GppA phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MVATHSHTQQHTLLKSQAPQTNAPANAKSRHFVAIDMGSNSFHLVIAREQDGSLQILHKEKQQVQLATGLNAQNILDNDA
IERGLNCLRDFNQRFSNLDQAQVRLVATHTLRIAKNRDQFIEAALAIMPYPVEVISGHEEARLIYNGIAQSQVLGKSNLV
IDIGGGSTEVVIGKKNTPTQLSSLRCGCVSFNERFFIDGLITPASFRDAQSAADKQFASLSKEYFAGGWELTLGSSGTVK
AICEAIQEEHGDETITLPRLKQLKIKLIKCGHISQIQFANVDDKRIPLVPAGLAILISFFRRLPIQKLEFSPGALREGVL
YELAKIGQYQDIRHRTVDSIAQLYHIDMAHAAKVRDTAMALFEQVADEWQLRPHARLLAYGATLHEIGLHINSKSLHKHG
GYIISNSDLPGFSEALQLDLARLITNHRKKPNELMLAELEPNHKLTLNRLLCLLRLAVLLNLGRIAKTLTLDHIKVIPDG
LMLVLPSHKRKISLFMKDLQREQKQMLTLGMNLRLVSSLT

Sequences:

>Translated_520_residues
MVATHSHTQQHTLLKSQAPQTNAPANAKSRHFVAIDMGSNSFHLVIAREQDGSLQILHKEKQQVQLATGLNAQNILDNDA
IERGLNCLRDFNQRFSNLDQAQVRLVATHTLRIAKNRDQFIEAALAIMPYPVEVISGHEEARLIYNGIAQSQVLGKSNLV
IDIGGGSTEVVIGKKNTPTQLSSLRCGCVSFNERFFIDGLITPASFRDAQSAADKQFASLSKEYFAGGWELTLGSSGTVK
AICEAIQEEHGDETITLPRLKQLKIKLIKCGHISQIQFANVDDKRIPLVPAGLAILISFFRRLPIQKLEFSPGALREGVL
YELAKIGQYQDIRHRTVDSIAQLYHIDMAHAAKVRDTAMALFEQVADEWQLRPHARLLAYGATLHEIGLHINSKSLHKHG
GYIISNSDLPGFSEALQLDLARLITNHRKKPNELMLAELEPNHKLTLNRLLCLLRLAVLLNLGRIAKTLTLDHIKVIPDG
LMLVLPSHKRKISLFMKDLQREQKQMLTLGMNLRLVSSLT
>Mature_520_residues
MVATHSHTQQHTLLKSQAPQTNAPANAKSRHFVAIDMGSNSFHLVIAREQDGSLQILHKEKQQVQLATGLNAQNILDNDA
IERGLNCLRDFNQRFSNLDQAQVRLVATHTLRIAKNRDQFIEAALAIMPYPVEVISGHEEARLIYNGIAQSQVLGKSNLV
IDIGGGSTEVVIGKKNTPTQLSSLRCGCVSFNERFFIDGLITPASFRDAQSAADKQFASLSKEYFAGGWELTLGSSGTVK
AICEAIQEEHGDETITLPRLKQLKIKLIKCGHISQIQFANVDDKRIPLVPAGLAILISFFRRLPIQKLEFSPGALREGVL
YELAKIGQYQDIRHRTVDSIAQLYHIDMAHAAKVRDTAMALFEQVADEWQLRPHARLLAYGATLHEIGLHINSKSLHKHG
GYIISNSDLPGFSEALQLDLARLITNHRKKPNELMLAELEPNHKLTLNRLLCLLRLAVLLNLGRIAKTLTLDHIKVIPDG
LMLVLPSHKRKISLFMKDLQREQKQMLTLGMNLRLVSSLT

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=485, Percent_Identity=40.8247422680412, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI48994966, Length=439, Percent_Identity=41.4578587699317, Blast_Score=326, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 57952; Mature: 57952

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVATHSHTQQHTLLKSQAPQTNAPANAKSRHFVAIDMGSNSFHLVIAREQDGSLQILHKE
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEECH
KQQVQLATGLNAQNILDNDAIERGLNCLRDFNQRFSNLDQAQVRLVATHTLRIAKNRDQF
HHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEECCCHHHH
IEAALAIMPYPVEVISGHEEARLIYNGIAQSQVLGKSNLVIDIGGGSTEVVIGKKNTPTQ
HHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCH
LSSLRCGCVSFNERFFIDGLITPASFRDAQSAADKQFASLSKEYFAGGWELTLGSSGTVK
HHHCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
AICEAIQEEHGDETITLPRLKQLKIKLIKCGHISQIQFANVDDKRIPLVPAGLAILISFF
HHHHHHHHHCCCCEEECCCHHCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHH
RRLPIQKLEFSPGALREGVLYELAKIGQYQDIRHRTVDSIAQLYHIDMAHAAKVRDTAMA
HHCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFEQVADEWQLRPHARLLAYGATLHEIGLHINSKSLHKHGGYIISNSDLPGFSEALQLDL
HHHHHHHHHCCCCCHHHHHHCCHHHHHCCCCCCCHHHHCCCEEEECCCCCCHHHHHHHHH
ARLITNHRKKPNELMLAELEPNHKLTLNRLLCLLRLAVLLNLGRIAKTLTLDHIKVIPDG
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
LMLVLPSHKRKISLFMKDLQREQKQMLTLGMNLRLVSSLT
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MVATHSHTQQHTLLKSQAPQTNAPANAKSRHFVAIDMGSNSFHLVIAREQDGSLQILHKE
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEECH
KQQVQLATGLNAQNILDNDAIERGLNCLRDFNQRFSNLDQAQVRLVATHTLRIAKNRDQF
HHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEEEEEEECCCHHHH
IEAALAIMPYPVEVISGHEEARLIYNGIAQSQVLGKSNLVIDIGGGSTEVVIGKKNTPTQ
HHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCH
LSSLRCGCVSFNERFFIDGLITPASFRDAQSAADKQFASLSKEYFAGGWELTLGSSGTVK
HHHCCCCEEECCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHH
AICEAIQEEHGDETITLPRLKQLKIKLIKCGHISQIQFANVDDKRIPLVPAGLAILISFF
HHHHHHHHHCCCCEEECCCHHCCEEEEEECCCCCEEEECCCCCCCCCCCCCHHHHHHHHH
RRLPIQKLEFSPGALREGVLYELAKIGQYQDIRHRTVDSIAQLYHIDMAHAAKVRDTAMA
HHCCCCEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFEQVADEWQLRPHARLLAYGATLHEIGLHINSKSLHKHGGYIISNSDLPGFSEALQLDL
HHHHHHHHHCCCCCHHHHHHCCHHHHHCCCCCCCHHHHCCCEEEECCCCCCHHHHHHHHH
ARLITNHRKKPNELMLAELEPNHKLTLNRLLCLLRLAVLLNLGRIAKTLTLDHIKVIPDG
HHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
LMLVLPSHKRKISLFMKDLQREQKQMLTLGMNLRLVSSLT
EEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]