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The map label for this gene is fadR [H]

Identifier: 160874930

GI number: 160874930

Start: 2178054

End: 2178770

Strand: Direct

Name: fadR [H]

Synonym: Sbal195_1815

Alternate gene names: 160874930

Gene position: 2178054-2178770 (Clockwise)

Preceding gene: 160874926

Following gene: 160874935

Centisome position: 40.73

GC content: 45.89

Gene sequence:

>717_bases
ATGATTATCAATGCCAAAGGACCTGCAAGTTTTGCAGAGAAGTATATTGTGAGATCCATTTGGGATAATAAATTTCCTCC
AGGGTCCATTTTACCGGCTGAACGTGAGCTTTCGGAATTGATAGGTGTGACTCGCACCACTCTGCGTGAAGTGCTACAGC
GCTTGGCCCGTGACGGTTGGTTGAAAATCCAACACGGTAAACCAACGCGAGTGAACAACTTCTGGGAAACCTCAGGCTTA
AACATTCTTGAGACGATTGCCGATCTCAATCCCGAAGGATTTCCGGTATTGGTTGACCAACTCTTGTCGGCCCGTACTAA
CGTTAGCGCTATCTATTTCCGCGGTGCTTTGCGTTATAACCCAGATACAGCTGTGGATGTGCTCGCCAAAATTCACCAAC
TTGAAGATACGGCGGAATCCTATGCCGAATTTGACTATTTATTGCACCACACCTTAGCTTTCTCCTCAGGGAATCCACTT
TACGTATTGATATTAAATGGATTTAAGGGATTGTATAGCCGAGTCGGTCGCTATTATTTTACCAGTTCCGATGCGCGTTT
ATTGGCTTTGAACTTTTACAAAGAGTTAGAGCTACTGGCTCAGGCGAAAAATTATCTCGACGTCCCCGCGCTGATGCGCA
CCTACGGCATGAACAGCGGTAAGATGTGGTTACAATTACGCGATGATATGCCCGCGTCTATCGCACAGGATAATTAA

Upstream 100 bases:

>100_bases
CGGCGATAACACAGTGAATTTAAGTGAATGGTTTCCATTTTTTACCGCTCTGGTATGATCAGTGACCATTACGACGCACA
ACAACTGGATAAGTGGGCTG

Downstream 100 bases:

>100_bases
TTGCTGCGATTGATGTCGCATTAAAATAGCGATAAATACATAAAAGCCGTTTCCAATGGAAACGGCTTTTTTATTCGGTT
TATTATTCTGGTTTAGCCGC

Product: fatty acid metabolism regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYNPDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFTSSDARLLALNFYKELELLAQAKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN

Sequences:

>Translated_238_residues
MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYNPDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFTSSDARLLALNFYKELELLAQAKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN
>Mature_238_residues
MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTRVNNFWETSGL
NILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYNPDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPL
YVLILNGFKGLYSRVGRYYFTSSDARLLALNFYKELELLAQAKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN

Specific function: Multifunctional regulator of fatty acid metabolism [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787436, Length=235, Percent_Identity=60, Blast_Score=301, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014178
- InterPro:   IPR008920
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07840 FadR_C; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26965; Mature: 26965

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYN
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECEEEEC
PDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCEEE
TSSDARLLALNFYKELELLAQAKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN
ECCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGW
CEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
LKIQHGKPTRVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRYN
EEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECEEEEC
PDTAVDVLAKIHQLEDTAESYAEFDYLLHHTLAFSSGNPLYVLILNGFKGLYSRVGRYYF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCEEE
TSSDARLLALNFYKELELLAQAKNYLDVPALMRTYGMNSGKMWLQLRDDMPASIAQDN
ECCCCEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA; DNA [C]

Specific reaction: Activates transcription of at least two genes required for unsaturated fatty acid biosynthesis; activates the iclR gene encoding the transcription regulator of the aceBAKoperon which in turn encodes the glyoxylate shunt enzymes Protein + DNA = Protein-DN

General reaction: NA

Inhibitor: Fatty acyl CoA compounds [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA