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The map label for this gene is bioA [H]

Identifier: 160874909

GI number: 160874909

Start: 2154618

End: 2155985

Strand: Reverse

Name: bioA [H]

Synonym: Sbal195_1794

Alternate gene names: 160874909

Gene position: 2155985-2154618 (Counterclockwise)

Preceding gene: 160874914

Following gene: 160874908

Centisome position: 40.32

GC content: 50.66

Gene sequence:

>1368_bases
ATGCGCAATTTACTCGATTTTGATTTTGATAGCGCCCATATTTGGCATCCTTACACCTCAATGACCCGTTCTCTTCCTGT
TTTTGGTGTACACAGCGCAAAGGGCTGCGAGCTCGAACTCGTCGATGGCCGCAAGCTAGTCGATGGCACTAGCTCATGGT
GGGCCTGTGTGCACGGCTATGCGCATCCCGAAATATTAACCGCAATGGAAAAACAGCTGCATCAGCTGAGCCATGTGATG
TTTGGCGGCATCACCCATGAGCCCGCCATTGAACTGTGCAAAAAACTTATCGCTATGACCTGCGAGCCGCTGACGAAAGT
CTTTTTATGCGACTCTGGCTCTATCTCAGTCGAAGTGGCGATCAAAATGGCGTTGCAATATTGGCAAGGTCAAAGTTTGC
AAGGTAAGAGCTCGCAGGGGCAAAGCGCACATAAAGAGCGGCCGCAAAAACAACGTATTCTTACCGTTAAGAAGGGTTAC
CACGGCGATACCTTTGCCGCCATGAGCGTGTGCGATCCCGAAGGTGGCATGCACACTATGTTTGGCGATGCGCTAACAAA
ACAATCCTTTGTGCCTGCACCACAAACCGCCTTTGGCGAAGCCTTACAAGCCGATGATTTAACCGCAATGCGCAGCATTT
TAAGTGCAAATCACCATGATATTGCCGCTGTGATCATAGAGCCGATCATGCAAGGTGCTGGCGGGATGCGTTTTTACAGC
GCGGATTATTTAGCGGGTATTCGCGCCCTGTGCGATGAATTTGATGTGTTGTTGATTTTAGATGAAATCGCCACAGGCTT
TGGCCGTACAGGTAAGCTGTTTGCCTATGAACACGCCAATATCACTCCAGATATCTTATGTTTAGGTAAAGCGCTAACGG
GCGGTTACATCAGCCTAGCGGCAACGCTGTGTACCGATAAAGTCGCCCAAGGAATCAGCCAGTCTAGCGCTGGCGTGTTT
ATGCATGGGCCGACATTTATGGGCAACCCGCTGGCCTGCACGGCGGCGTGTGCGAGCTTAGACTTAATTAACCGCAATGA
ATGGCAAACGCAAGTGGCCGCTATCGAGCAGCAAATGCGCTTAGAACTTAAGGATGCGATTGATTTACCGAGTGTTAAGG
ACGTGCGAGTCCTCGGCGCTGTCGGTGTGTTAGAGATGCATGATCCCGTCAATACCGCAGAGCTACAGCAACAATTTGTT
GATTTAGGGGTGTGGGTTCGCCCCTTCGCTAACCTTATCTATATCATGCCACCCTATGTGATTAGCTCGGCGCAATTAAG
CCAACTCACCGGTGCGATGAAGCAAGTCGCGGCAGGCATTAGTGCAACATCCACCAGTGCCGAGCCACAACTTATCAGCC
ACGGCTAA

Upstream 100 bases:

>100_bases
TTTTATCTTGGCTAGGATAACCTCAGCCCTTAAACTGTCAACGCCAACCAGTGAATCCAGTTTACTAATGGCTATTTTAC
CACCAACTTAGTGAGCATTT

Downstream 100 bases:

>100_bases
TGCCAACAGCATAAGCCTTCAACGTAATAATCCTTCAAATAGACAACACTCAGCGCACCGTTCTAGGTGCGCTGGGGTTA
AACTTTAAGTGACTCGGCAG

Product: adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MRNLLDFDFDSAHIWHPYTSMTRSLPVFGVHSAKGCELELVDGRKLVDGTSSWWACVHGYAHPEILTAMEKQLHQLSHVM
FGGITHEPAIELCKKLIAMTCEPLTKVFLCDSGSISVEVAIKMALQYWQGQSLQGKSSQGQSAHKERPQKQRILTVKKGY
HGDTFAAMSVCDPEGGMHTMFGDALTKQSFVPAPQTAFGEALQADDLTAMRSILSANHHDIAAVIIEPIMQGAGGMRFYS
ADYLAGIRALCDEFDVLLILDEIATGFGRTGKLFAYEHANITPDILCLGKALTGGYISLAATLCTDKVAQGISQSSAGVF
MHGPTFMGNPLACTAACASLDLINRNEWQTQVAAIEQQMRLELKDAIDLPSVKDVRVLGAVGVLEMHDPVNTAELQQQFV
DLGVWVRPFANLIYIMPPYVISSAQLSQLTGAMKQVAAGISATSTSAEPQLISHG

Sequences:

>Translated_455_residues
MRNLLDFDFDSAHIWHPYTSMTRSLPVFGVHSAKGCELELVDGRKLVDGTSSWWACVHGYAHPEILTAMEKQLHQLSHVM
FGGITHEPAIELCKKLIAMTCEPLTKVFLCDSGSISVEVAIKMALQYWQGQSLQGKSSQGQSAHKERPQKQRILTVKKGY
HGDTFAAMSVCDPEGGMHTMFGDALTKQSFVPAPQTAFGEALQADDLTAMRSILSANHHDIAAVIIEPIMQGAGGMRFYS
ADYLAGIRALCDEFDVLLILDEIATGFGRTGKLFAYEHANITPDILCLGKALTGGYISLAATLCTDKVAQGISQSSAGVF
MHGPTFMGNPLACTAACASLDLINRNEWQTQVAAIEQQMRLELKDAIDLPSVKDVRVLGAVGVLEMHDPVNTAELQQQFV
DLGVWVRPFANLIYIMPPYVISSAQLSQLTGAMKQVAAGISATSTSAEPQLISHG
>Mature_455_residues
MRNLLDFDFDSAHIWHPYTSMTRSLPVFGVHSAKGCELELVDGRKLVDGTSSWWACVHGYAHPEILTAMEKQLHQLSHVM
FGGITHEPAIELCKKLIAMTCEPLTKVFLCDSGSISVEVAIKMALQYWQGQSLQGKSSQGQSAHKERPQKQRILTVKKGY
HGDTFAAMSVCDPEGGMHTMFGDALTKQSFVPAPQTAFGEALQADDLTAMRSILSANHHDIAAVIIEPIMQGAGGMRFYS
ADYLAGIRALCDEFDVLLILDEIATGFGRTGKLFAYEHANITPDILCLGKALTGGYISLAATLCTDKVAQGISQSSAGVF
MHGPTFMGNPLACTAACASLDLINRNEWQTQVAAIEQQMRLELKDAIDLPSVKDVRVLGAVGVLEMHDPVNTAELQQQFV
DLGVWVRPFANLIYIMPPYVISSAQLSQLTGAMKQVAAGISATSTSAEPQLISHG

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=427, Percent_Identity=29.7423887587822, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI284507298, Length=286, Percent_Identity=30.7692307692308, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI13994255, Length=379, Percent_Identity=28.7598944591029, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI226442709, Length=424, Percent_Identity=24.5283018867925, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI37574042, Length=424, Percent_Identity=24.2924528301887, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI226442705, Length=430, Percent_Identity=23.953488372093, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1786991, Length=430, Percent_Identity=58.8372093023256, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI145693181, Length=314, Percent_Identity=35.031847133758, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789016, Length=422, Percent_Identity=28.9099526066351, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789759, Length=343, Percent_Identity=31.4868804664723, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1788044, Length=324, Percent_Identity=33.641975308642, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1787560, Length=416, Percent_Identity=28.6057692307692, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1786349, Length=319, Percent_Identity=28.2131661442006, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144271, Length=429, Percent_Identity=27.5058275058275, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI25144274, Length=280, Percent_Identity=30.3571428571429, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI32564660, Length=425, Percent_Identity=24.2352941176471, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71992977, Length=418, Percent_Identity=22.0095693779904, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17541228, Length=391, Percent_Identity=23.2736572890026, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324386, Length=470, Percent_Identity=43.4042553191489, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6323470, Length=436, Percent_Identity=31.4220183486239, Blast_Score=144, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324432, Length=375, Percent_Identity=29.0666666666667, Blast_Score=136, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6321456, Length=313, Percent_Identity=23.961661341853, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357415, Length=426, Percent_Identity=28.169014084507, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=363, Percent_Identity=23.6914600550964, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28574759, Length=432, Percent_Identity=25.462962962963, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=25.1173708920188, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281366494, Length=286, Percent_Identity=26.2237762237762, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667139, Length=286, Percent_Identity=26.2237762237762, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24667143, Length=286, Percent_Identity=26.2237762237762, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 49299; Mature: 49299

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLLDFDFDSAHIWHPYTSMTRSLPVFGVHSAKGCELELVDGRKLVDGTSSWWACVHGY
CCCCCCCCCCCCEEECCHHHHHHCCCEEECCCCCCCEEEEECCCEEECCCCHHHHHHCCC
AHPEILTAMEKQLHQLSHVMFGGITHEPAIELCKKLIAMTCEPLTKVFLCDSGSISVEVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHEEEEECCCCEEEHHH
IKMALQYWQGQSLQGKSSQGQSAHKERPQKQRILTVKKGYHGDTFAAMSVCDPEGGMHTM
HHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHEEEEECCCCCCCEEEEEEECCCCCCCHH
FGDALTKQSFVPAPQTAFGEALQADDLTAMRSILSANHHDIAAVIIEPIMQGAGGMRFYS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEC
ADYLAGIRALCDEFDVLLILDEIATGFGRTGKLFAYEHANITPDILCLGKALTGGYISLA
HHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHH
ATLCTDKVAQGISQSSAGVFMHGPTFMGNPLACTAACASLDLINRNEWQTQVAAIEQQMR
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LELKDAIDLPSVKDVRVLGAVGVLEMHDPVNTAELQQQFVDLGVWVRPFANLIYIMPPYV
HHHHHHCCCCCCCCCHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCHH
ISSAQLSQLTGAMKQVAAGISATSTSAEPQLISHG
HCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRNLLDFDFDSAHIWHPYTSMTRSLPVFGVHSAKGCELELVDGRKLVDGTSSWWACVHGY
CCCCCCCCCCCCEEECCHHHHHHCCCEEECCCCCCCEEEEECCCEEECCCCHHHHHHCCC
AHPEILTAMEKQLHQLSHVMFGGITHEPAIELCKKLIAMTCEPLTKVFLCDSGSISVEVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHEEEEECCCCEEEHHH
IKMALQYWQGQSLQGKSSQGQSAHKERPQKQRILTVKKGYHGDTFAAMSVCDPEGGMHTM
HHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHEEEEECCCCCCCEEEEEEECCCCCCCHH
FGDALTKQSFVPAPQTAFGEALQADDLTAMRSILSANHHDIAAVIIEPIMQGAGGMRFYS
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEC
ADYLAGIRALCDEFDVLLILDEIATGFGRTGKLFAYEHANITPDILCLGKALTGGYISLA
HHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHH
ATLCTDKVAQGISQSSAGVFMHGPTFMGNPLACTAACASLDLINRNEWQTQVAAIEQQMR
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LELKDAIDLPSVKDVRVLGAVGVLEMHDPVNTAELQQQFVDLGVWVRPFANLIYIMPPYV
HHHHHHCCCCCCCCCHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHHCEEEECCCHH
ISSAQLSQLTGAMKQVAAGISATSTSAEPQLISHG
HCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8890743 [H]