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The map label for this gene is acsA [H]

Identifier: 160874906

GI number: 160874906

Start: 2146903

End: 2148855

Strand: Reverse

Name: acsA [H]

Synonym: Sbal195_1791

Alternate gene names: 160874906

Gene position: 2148855-2146903 (Counterclockwise)

Preceding gene: 160874908

Following gene: 160874905

Centisome position: 40.19

GC content: 49.56

Gene sequence:

>1953_bases
ATGAGCTCGCAGTCTCTCTACAAAGTCTCCGGCAATATCGCTGCCAATGCACTTGTAAACAACGATAAATATAAAACAAT
GTACCAAGAGTCGATTGTCAATCCTGAAGGTTTCTGGAGAGAACACGGCAAGCGTATTGATTGGATAAAACCCTATACCA
AAATTAAAAAAACCTCTTTTGATGATCATAATTTATCGATCAACTGGTTTTACGACGGCACCCTAAATGCTTCTGCCAAC
TGTTTAGATCGTCACTTAGCTGAGCACAGTGATCGCGTGGCGATTATTTGGGAAGGCGACAACGCCAGCGAACAACGCAA
AATTACCTACGGTGAATTACATGCAGAGGTGTGTAAATTCGCTAACGCATTACGCAGCCAAGGCGTGCGCCGCGGTGACA
TAGTCACGATTTACATGCCTATGGTGCCAGAAGCCGCAGTGGCTATGCTCGCCTGTGCCCGTATCGGCGCTGTGCACTCC
GTGGTCTTCGGTGGTTTCTCACCGGATTCTATCGCCTCTCGCGTGATTGATGGCAAATCAAAAGTCATTATTACCTCAGA
TGAAGGTATGCGCGGTGGCCGTGCTATCCCATTGAAACGCAACATCGATGATGCCTTAAAAAATCCTGATGTTACTACGG
TTGAGAAAGTCATAGTGCTGAAGCGCACGGGCGGCATAGTGGATTGGGTAGAAGACCGAGATGTGTGGTGGCACTCACTG
ATGGAAACCGCATCTGAGTACTGCCAACCAGAGGAAATGGATGCCGAAGCGCCGTTATTCCTGCTGTATACCTCAGGTTC
AACCGGTAATCCCAAGGGCGTATTGCACACCACTGGTGGCTACATGGTTTATGCGTCTATGACCCATGAATATGTGTTCG
ACTACAAAGCGGGCGAAGTGTACTGGTGTACCGCCGATGTGGGTTGGATCACTGGCCACTCTTATATGGTTTACGGCCCA
CTCGCCAATGGTGCGACTGTGCTCATCCATGAAGGCGTTCCGAATCATCCAAGCCCTGCCCGTTTAGGCGAAATGATTGA
CCGCCATAAAGTGAGCATTCTTTACACAGCGCCAACTTTAATTCGCGCGCTGATGGCCGAAGGTAAACAACACTTCGATA
AGTTCGATGGTAGCAGCTTGAGGATCATGGGCTCAGTAGGCGAACCCATCAACCCAGAAGCATGGCGTTGGTACCATGAA
GTCATAGGTCATGAACATTGCCCTATCGTCGATACTTGGTGGCAAACTGAAACTGGCGGTATTTTGATCACGCCACTGCC
TGGGGCGACCGACACTAAACCTGGTTCAGCGACCCGTCCGTTCTTTGGCGTTCAACCTGCCTTAGTCGATAACATGGGTA
ATATTTTAGAGGGTGAGAACGAAGGTAACTTAGTGTTACTCGACTCTTGGCCGGGCCAAATGCGAACTGTATATGGCGAC
CACGAACGATTCGTACTGACCTATTTTAAAACCTTCCGTGGCATGTATTTTACCGGTGACGGTGCCCGTCGCGATGAAGA
TGGTTACTACTGGATAACAGGCCGCGTCGATGACGTGATCAACGTATCCGGCCACAGATTAGGTACGGCAGAGGTAGAAA
GTGCGCTGGTATCACATGAACTGGTTGCAGAAGCTGCAGTAGTTGGCTACCCACACGATATTAAAGGCCAAGGTATTTAT
GCGTATGTCACGCTAACCCGCGGCACTGAAGAAACCGAAGAGCTACGTCAAGAGCTGCGTCAATGGGTCCGTAAAGAAAT
TGGTGCGCTGGCAACCCCAGATCTCATCCAATGGGCGACAGGCTTACCTAAGACTCGTTCGGGCAAGATCATGCGCCGCT
TCCTGCGTAAGATTGCCGCTAACGAAGTGACCAATTTAGGGGATGCATCAACCTTGGCCGATCCAGCTGTGATCGAGACC
TTGATTGAATCACGCTTGAATCGTACTGAGTAA

Upstream 100 bases:

>100_bases
AAATATAAAGGAAAATTTAAAACTAGACCAAGGTCTAATGGAGTTGCCGCCCCCTTGCATACCATACTCAGTCCACGCAA
TTTTTCAAAAGGGAAGCCCT

Downstream 100 bases:

>100_bases
TATCCGAGTTACGAACAACGTCCACAACGCTTAGTCGATGCCCAATAGGCTAAGCGTAACCTGAACCTCCCTTTTGAAAC
CTCAGGTTAAAAGTGAACCC

Product: acetyl-CoA synthetase

Products: NA

Alternate protein names: Acetate--CoA ligase; Acyl-activating enzyme [H]

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MSSQSLYKVSGNIAANALVNNDKYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTSFDDHNLSINWFYDGTLNASAN
CLDRHLAEHSDRVAIIWEGDNASEQRKITYGELHAEVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHS
VVFGGFSPDSIASRVIDGKSKVIITSDEGMRGGRAIPLKRNIDDALKNPDVTTVEKVIVLKRTGGIVDWVEDRDVWWHSL
METASEYCQPEEMDAEAPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKAGEVYWCTADVGWITGHSYMVYGP
LANGATVLIHEGVPNHPSPARLGEMIDRHKVSILYTAPTLIRALMAEGKQHFDKFDGSSLRIMGSVGEPINPEAWRWYHE
VIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGENEGNLVLLDSWPGQMRTVYGD
HERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIY
AYVTLTRGTEETEELRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIET
LIESRLNRTE

Sequences:

>Translated_650_residues
MSSQSLYKVSGNIAANALVNNDKYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTSFDDHNLSINWFYDGTLNASAN
CLDRHLAEHSDRVAIIWEGDNASEQRKITYGELHAEVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHS
VVFGGFSPDSIASRVIDGKSKVIITSDEGMRGGRAIPLKRNIDDALKNPDVTTVEKVIVLKRTGGIVDWVEDRDVWWHSL
METASEYCQPEEMDAEAPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKAGEVYWCTADVGWITGHSYMVYGP
LANGATVLIHEGVPNHPSPARLGEMIDRHKVSILYTAPTLIRALMAEGKQHFDKFDGSSLRIMGSVGEPINPEAWRWYHE
VIGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGENEGNLVLLDSWPGQMRTVYGD
HERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIY
AYVTLTRGTEETEELRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIET
LIESRLNRTE
>Mature_649_residues
SSQSLYKVSGNIAANALVNNDKYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTSFDDHNLSINWFYDGTLNASANC
LDRHLAEHSDRVAIIWEGDNASEQRKITYGELHAEVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSV
VFGGFSPDSIASRVIDGKSKVIITSDEGMRGGRAIPLKRNIDDALKNPDVTTVEKVIVLKRTGGIVDWVEDRDVWWHSLM
ETASEYCQPEEMDAEAPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKAGEVYWCTADVGWITGHSYMVYGPL
ANGATVLIHEGVPNHPSPARLGEMIDRHKVSILYTAPTLIRALMAEGKQHFDKFDGSSLRIMGSVGEPINPEAWRWYHEV
IGHEHCPIVDTWWQTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGENEGNLVLLDSWPGQMRTVYGDH
ERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHELVAEAAVVGYPHDIKGQGIYA
YVTLTRGTEETEELRQELRQWVRKEIGALATPDLIQWATGLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIETL
IESRLNRTE

Specific function: Enables The Cell To Use Acetate During Aerobic Growth To Generate Energy Via The Tca Cycle, And Biosynthetic Compounds Via The Glyoxylate Shunt. Acetylates Chey, The Response Regulator Involved In Flagellar Movement And Chemotaxis. [C]

COG id: COG0365

COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI8923896, Length=654, Percent_Identity=52.5993883792049, Blast_Score=682, Evalue=0.0,
Organism=Homo sapiens, GI253970489, Length=667, Percent_Identity=51.5742128935532, Blast_Score=677, Evalue=0.0,
Organism=Homo sapiens, GI28416953, Length=623, Percent_Identity=49.1171749598716, Blast_Score=627, Evalue=1e-180,
Organism=Homo sapiens, GI13375727, Length=634, Percent_Identity=35.9621451104101, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI42544132, Length=564, Percent_Identity=29.0780141843972, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI122937307, Length=552, Percent_Identity=28.804347826087, Blast_Score=199, Evalue=7e-51,
Organism=Homo sapiens, GI38505220, Length=541, Percent_Identity=29.7597042513863, Blast_Score=190, Evalue=4e-48,
Organism=Homo sapiens, GI31982927, Length=645, Percent_Identity=24.8062015503876, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI115511026, Length=534, Percent_Identity=28.6516853932584, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI58082049, Length=525, Percent_Identity=26.0952380952381, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI157311624, Length=525, Percent_Identity=25.3333333333333, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI157311622, Length=525, Percent_Identity=25.3333333333333, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI195947378, Length=442, Percent_Identity=24.8868778280543, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI42544134, Length=383, Percent_Identity=25.065274151436, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI187761345, Length=581, Percent_Identity=24.7848537005164, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI187761343, Length=581, Percent_Identity=24.7848537005164, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI156151445, Length=572, Percent_Identity=23.6013986013986, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI1790505, Length=645, Percent_Identity=68.9922480620155, Blast_Score=967, Evalue=0.0,
Organism=Escherichia coli, GI1786529, Length=634, Percent_Identity=37.5394321766561, Blast_Score=400, Evalue=1e-112,
Organism=Escherichia coli, GI1788107, Length=575, Percent_Identity=23.6521739130435, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI221142682, Length=532, Percent_Identity=21.9924812030075, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI145693145, Length=551, Percent_Identity=23.049001814882, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786810, Length=552, Percent_Identity=21.9202898550725, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789201, Length=460, Percent_Identity=23.2608695652174, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983001, Length=640, Percent_Identity=50.625, Blast_Score=627, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI71982997, Length=640, Percent_Identity=50.625, Blast_Score=627, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17569507, Length=621, Percent_Identity=22.866344605475, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17558820, Length=523, Percent_Identity=24.6653919694073, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32563687, Length=557, Percent_Identity=22.8007181328546, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17538037, Length=142, Percent_Identity=31.6901408450704, Blast_Score=76, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17557194, Length=132, Percent_Identity=32.5757575757576, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323182, Length=641, Percent_Identity=49.2979719188768, Blast_Score=628, Evalue=1e-180,
Organism=Saccharomyces cerevisiae, GI6319264, Length=641, Percent_Identity=46.801872074883, Blast_Score=573, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319699, Length=373, Percent_Identity=23.0563002680965, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24667955, Length=664, Percent_Identity=53.0120481927711, Blast_Score=687, Evalue=0.0,
Organism=Drosophila melanogaster, GI62472339, Length=562, Percent_Identity=57.1174377224199, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI24667959, Length=520, Percent_Identity=57.8846153846154, Blast_Score=600, Evalue=1e-172,
Organism=Drosophila melanogaster, GI21355225, Length=659, Percent_Identity=33.8391502276176, Blast_Score=360, Evalue=2e-99,
Organism=Drosophila melanogaster, GI18859661, Length=554, Percent_Identity=22.5631768953069, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21355181, Length=526, Percent_Identity=23.7642585551331, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24581924, Length=527, Percent_Identity=22.7703984819734, Blast_Score=79, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24656500, Length=541, Percent_Identity=22.181146025878, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011904
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.1 [H]

Molecular weight: Translated: 72454; Mature: 72323

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQSLYKVSGNIAANALVNNDKYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTSF
CCCCCEEEECCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHCCCC
DDHNLSINWFYDGTLNASANCLDRHLAEHSDRVAIIWEGDNASEQRKITYGELHAEVCKF
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
ANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASRVIDGKS
HHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
KVIITSDEGMRGGRAIPLKRNIDDALKNPDVTTVEKVIVLKRTGGIVDWVEDRDVWWHSL
EEEEECCCCCCCCEEECCCCCCHHHHCCCCCCCEEEEEEEEECCCEEEECCCCHHHHHHH
METASEYCQPEEMDAEAPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKAGEV
HHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEECCEEEEEEECCCEE
YWCTADVGWITGHSYMVYGPLANGATVLIHEGVPNHPSPARLGEMIDRHKVSILYTAPTL
EEEECCCCEEECCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECHHH
IRALMAEGKQHFDKFDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGG
HHHHHHHCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCC
ILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGENEGNLVLLDSWPGQMRTVYGD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCCCEEEEECCCCCEEEEECC
HERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHE
CCHHHHEEHHHHCCEEEECCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHH
LVAEAAVVGYPHDIKGQGIYAYVTLTRGTEETEELRQELRQWVRKEIGALATPDLIQWAT
HHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
GLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIETLIESRLNRTE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSQSLYKVSGNIAANALVNNDKYKTMYQESIVNPEGFWREHGKRIDWIKPYTKIKKTSF
CCCCEEEECCCEEEEEEECCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHCCCC
DDHNLSINWFYDGTLNASANCLDRHLAEHSDRVAIIWEGDNASEQRKITYGELHAEVCKF
CCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHH
ANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASRVIDGKS
HHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
KVIITSDEGMRGGRAIPLKRNIDDALKNPDVTTVEKVIVLKRTGGIVDWVEDRDVWWHSL
EEEEECCCCCCCCEEECCCCCCHHHHCCCCCCCEEEEEEEEECCCEEEECCCCHHHHHHH
METASEYCQPEEMDAEAPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFDYKAGEV
HHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEECCEEEEEEECCCEE
YWCTADVGWITGHSYMVYGPLANGATVLIHEGVPNHPSPARLGEMIDRHKVSILYTAPTL
EEEECCCCEEECCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECHHH
IRALMAEGKQHFDKFDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWWQTETGG
HHHHHHHCHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCC
ILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGENEGNLVLLDSWPGQMRTVYGD
EEEECCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHCCCCCCCEEEEECCCCCEEEEECC
HERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVESALVSHE
CCHHHHEEHHHHCCEEEECCCCCCCCCCEEEEECCCCCEEECCCCCCCHHHHHHHHHHHH
LVAEAAVVGYPHDIKGQGIYAYVTLTRGTEETEELRQELRQWVRKEIGALATPDLIQWAT
HHHHHHHCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHC
GLPKTRSGKIMRRFLRKIAANEVTNLGDASTLADPAVIETLIESRLNRTE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA