Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 160874876

GI number: 160874876

Start: 2108840

End: 2110078

Strand: Direct

Name: fabF [H]

Synonym: Sbal195_1761

Alternate gene names: 160874876

Gene position: 2108840-2110078 (Clockwise)

Preceding gene: 160874875

Following gene: 160874877

Centisome position: 39.44

GC content: 48.75

Gene sequence:

>1239_bases
GTGTCTAAACGTCGTGTAGTGGTAACCGGTTTGGGGTTAGTAACTCCAGTGGGCAATACTGTCGATACTACTTGGAAGGC
TTTGCTTTCTGGTAAGAGTGGTATTGCACCGATAACCAAATTTGATGCCAGTGAATTTACCACTCGTTTCAGTGGTTCAG
TAAAAGATTTCGATGTTGAGCAATACTTAACGAAAAAAGATGCCCGTAAGATGGACCTCTTTATTCAATATGGTATGGCG
GCTGGCATTCAAGCTATCCAAGACTCAGGTCTGGATATGAGCAAAGAAAACCCAGGTCGTGTCGGTACGGCTATTGGTGC
GGGTATGGGCGGTATGTGGTTAATTGAACAAAACCACAGCGCACTGATCAACGGCGGTCCGCGTAAGGTTTCTCCTTTTT
TCGTTCCTAGTACCATTATCAATATGATTTCGGGTCACTTGTCGATCATGTTTGGCATGAAAGGGCCAAATTTTGCCGTG
ACCACCGCTTGTACTACGGGCGTGCATAATATCGGTTTTGCAGCGCGTACCATTGCCTATGGCGATGCCGACGTGATGGT
TGCAGGCGGTGCTGAGGATGTCACTTCTCCTTTAGGCGTGGCAGGTTTTGGCGCTGCGAAAGCATTATCGACACGCAATG
ACGATCCGACTGCGGCAAGTCGTCCATGGGATAAAGACCGTGATGGTTTTGTTATCGGTGATGGCGCAGGTGTGATGGTG
ATGGAAGAGTACGAACACGCTAAAGCGCGCGGTGCGACCATTTACGGCGAGTTAGTCGGTTTTGGTATGAGCGGTGATGC
TTTCCACATGACATCGCCTCCAAGCGACGGTGCTGGCGCTGCTGCGGCTATGGTCAATGCCATTAATGACGCTAAGCTAT
CACTGGAGCAAATTGGCTATATCAACGCGCACGGTACGTCGACGCCAGCAGGTGATAAAGCAGAAGCGGCAGCGGTTAAG
TCAGTATTTGGCGATCACGCCTATAAAGTGCTGGTTAGCTCGACTAAATCGATGACGGGTCACCTCTTAGGTGCTGCAGG
TGCAGTTGAAGCGATTTTCACCTTACTAGCACTGCGCGACCAAGCTGTTCCGCCAACCATCAATTTGGATAATCCAGATG
AAGGTTGTGATTTAGACTTTGTTGCTCATACTGCCCGTGACGTGAAGATGGATTACGCTCTGTGTAATTCCTTCGGTTTT
GGTGGGACTAACGGTTCATTACTGTTTAAGAAAGTGTAA

Upstream 100 bases:

>100_bases
GAATTTTTCTAAATAAACGTTATTTAAGAAACTGTCTAATGATAGAAAACCTTGTTTTATCTATCAGAACTAACAAATTT
AGCATTTAAAGGTGACTGCC

Downstream 100 bases:

>100_bases
AACTTGCATTGATAGTGCAAAAAACAGTGAAGAAATGCGCCTGAGGGCGCATTTTTTATGGATAAAATCCATTGAGATTG
TGAATTGAGTAGCATTATTT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase 2

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVEQYLTKKDARKMDLFIQYGMA
AGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHSALINGGPRKVSPFFVPSTIINMISGHLSIMFGMKGPNFAV
TTACTTGVHNIGFAARTIAYGDADVMVAGGAEDVTSPLGVAGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAINDAKLSLEQIGYINAHGTSTPAGDKAEAAAVK
SVFGDHAYKVLVSSTKSMTGHLLGAAGAVEAIFTLLALRDQAVPPTINLDNPDEGCDLDFVAHTARDVKMDYALCNSFGF
GGTNGSLLFKKV

Sequences:

>Translated_412_residues
MSKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVEQYLTKKDARKMDLFIQYGMA
AGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHSALINGGPRKVSPFFVPSTIINMISGHLSIMFGMKGPNFAV
TTACTTGVHNIGFAARTIAYGDADVMVAGGAEDVTSPLGVAGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAINDAKLSLEQIGYINAHGTSTPAGDKAEAAAVK
SVFGDHAYKVLVSSTKSMTGHLLGAAGAVEAIFTLLALRDQAVPPTINLDNPDEGCDLDFVAHTARDVKMDYALCNSFGF
GGTNGSLLFKKV
>Mature_411_residues
SKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVEQYLTKKDARKMDLFIQYGMAA
GIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHSALINGGPRKVSPFFVPSTIINMISGHLSIMFGMKGPNFAVT
TACTTGVHNIGFAARTIAYGDADVMVAGGAEDVTSPLGVAGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMVM
EEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAINDAKLSLEQIGYINAHGTSTPAGDKAEAAAVKS
VFGDHAYKVLVSSTKSMTGHLLGAAGAVEAIFTLLALRDQAVPPTINLDNPDEGCDLDFVAHTARDVKMDYALCNSFGFG
GTNGSLLFKKV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=47.3557692307692, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI223972627, Length=162, Percent_Identity=51.8518518518518, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI41872631, Length=404, Percent_Identity=24.5049504950495, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=72.3970944309927, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=39.4230769230769, Blast_Score=250, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=39.5631067961165, Blast_Score=280, Evalue=8e-76,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=45.8333333333333, Blast_Score=224, Evalue=6e-59,
Organism=Caenorhabditis elegans, GI212642053, Length=355, Percent_Identity=24.7887323943662, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=352, Percent_Identity=23.8636363636364, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=41.7040358744395, Blast_Score=306, Evalue=5e-84,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=45.3012048192771, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI221330659, Length=374, Percent_Identity=24.5989304812834, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920632, Length=374, Percent_Identity=24.5989304812834, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24581345, Length=374, Percent_Identity=22.9946524064171, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42909; Mature: 42778

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVE
CCCCEEEEEECCEECCCCCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHCCCCCCCCHH
QYLTKKDARKMDLFIQYGMAAGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHS
HHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCCCEEEEECCCC
ALINGGPRKVSPFFVPSTIINMISGHLSIMFGMKGPNFAVTTACTTGVHNIGFAARTIAY
EEECCCCCCCCCEECHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCHHCCCCEEEEEE
GDADVMVAGGAEDVTSPLGVAGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
CCCCEEEECCCHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAINDAKLSLEQIGY
EECHHHHHHCCCEEEEHHEECCCCCCEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHCCE
INAHGTSTPAGDKAEAAAVKSVFGDHAYKVLVSSTKSMTGHLLGAAGAVEAIFTLLALRD
EECCCCCCCCCCCHHHHHHHHHHCCHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
QAVPPTINLDNPDEGCDLDFVAHTARDVKMDYALCNSFGFGGTNGSLLFKKV
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVE
CCCEEEEEECCEECCCCCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHCCCCCCCCHH
QYLTKKDARKMDLFIQYGMAAGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHS
HHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCCCEEEEECCCC
ALINGGPRKVSPFFVPSTIINMISGHLSIMFGMKGPNFAVTTACTTGVHNIGFAARTIAY
EEECCCCCCCCCEECHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCHHCCCCEEEEEE
GDADVMVAGGAEDVTSPLGVAGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
CCCCEEEECCCHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAINDAKLSLEQIGY
EECHHHHHHCCCEEEEHHEECCCCCCEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHCCE
INAHGTSTPAGDKAEAAAVKSVFGDHAYKVLVSSTKSMTGHLLGAAGAVEAIFTLLALRD
EECCCCCCCCCCCHHHHHHHHHHCCHHEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
QAVPPTINLDNPDEGCDLDFVAHTARDVKMDYALCNSFGFGGTNGSLLFKKV
CCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]